Have a deep view into what people are curious about.

🔗 Physics

Absolute hot is a theoretical upper limit to the thermodynamic temperature scale, conceived as an opposite to absolute zero.

🔗 Computing 🔗 Computing/Software 🔗 Computing/Free and open-source software 🔗 C/C++ 🔗 C/C++/C

Cairo (stylized as cairo) is an open-source graphics library that provides a vector graphics-based, device-independent API for software developers. It provides primitives for two-dimensional drawing across a number of different back ends. Cairo uses hardware acceleration when available.

🔗 Psychology

The behavioral immune system is a phrase coined by the psychological scientist Mark Schaller to refer to a suite of psychological mechanisms that allow individual organisms to detect the potential presence of disease-causing parasites in their immediate environment, and to engage in behaviors that prevent contact with those objects and individuals.

These mechanisms include sensory processes through which cues connoting the presence of parasitic infections are perceived (e.g., the smell of a foul odor, the sight of pox or pustules), as well as stimulus–response systems through which these sensory cues trigger a cascade of aversive affective, cognitive, and behavioral reactions (e.g., arousal of disgust, automatic activation of cognitions that connote the threat of disease, behavioral avoidance).

The existence of a behavioral immune system has been documented across many animal species, including humans. It is theorized that the mechanisms that comprise the behavioral immune system evolved as a crude first line of defense against disease-causing pathogens.

🔗 Philosophy 🔗 Philosophy/Logic

Erotetics or erotetic logic is a part of logic, devoted to logical analysis of questions. It is sometimes called the logic of questions and answers.

🔗 London 🔗 Books 🔗 Sexology and sexuality 🔗 Sexology and sexuality/Sex work

Harris's List of Covent Garden Ladies, published from 1757 to 1795, was an annual directory of prostitutes then working in Georgian London. A small pocketbook, it was printed and published in Covent Garden, and sold for two shillings and sixpence. A contemporary report of 1791 estimates its circulation at about 8,000 copies annually.

Each edition contains entries describing the physical appearance and sexual specialities of about 120–190 prostitutes who worked in and around Covent Garden. Through their erotic prose, the list's entries review some of these women in lurid detail. While most compliment their subjects, some are critical of bad habits, and a few women are even treated as pariahs, perhaps having fallen out of favour with the list's authors, who are never revealed.

Samuel Derrick is the man normally credited for the design of Harris's List, possibly having been inspired by the activities of a Covent Garden pimp, Jack Harris. A Grub Street hack, Derrick may have written the lists from 1757 until his death in 1769; thereafter, the annual's authors are unknown. Throughout its print run it was published pseudonymously by H. Ranger, although from the late 1780s it was printed by three men: John and James Roach, and John Aitkin.

As the public's opinion began to turn against London's sex trade, and with reformers petitioning the authorities to take action, those involved in the release of Harris's List were in 1795 fined and imprisoned. That year's edition was the last to be published. By then, its content was cruder, lacking the originality of earlier editions. Modern writers tend to view Harris's List as erotica; in the words of one author, it was designed for "solitary sexual enjoyment".

🔗 Biography 🔗 Literature 🔗 Women writers 🔗 Biography/arts and entertainment

Barbara Newhall Follett (March 4, 1914 – disappeared December 7, 1939) was an American child prodigy novelist. Her first novel, The House Without Windows, was published in January 1927, when she was twelve years old. Her next novel, The Voyage of the Norman D.w, received critical acclaim when she was fourteen.

In December 1939, aged 25, Follett reportedly became depressed with her marriage and walked out of her apartment, never to be seen again.

🔗 Skepticism 🔗 Neuroscience 🔗 Physiology

The gut–brain axis is the two-way biochemical signaling that takes place between the gastrointestinal tract (GI tract) and the central nervous system (CNS). The term "gut–brain axis" is occasionally used to refer to the role of the gut microbiota in the interplay as well. The "microbiota–gut–brain (MGB or BGM) axis" explicitly includes the role of gut microbiota in the biochemical signaling events that take place between the GI tract and the CNS. Broadly defined, the gut–brain axis includes the central nervous system, neuroendocrine system, neuroimmune systems, the hypothalamic–pituitary–adrenal axis (HPA axis), sympathetic and parasympathetic arms of the autonomic nervous system, the enteric nervous system, vagus nerve, and the gut microbiota.

Chemicals released in the gut by the microbiome can vastly influence the development of the brain, starting from birth. A review from 2015 states that the microbiome influences the central nervous system by “regulating brain chemistry and influencing neuro-endocrine systems associated with stress response, anxiety and memory function”. The gut, sometimes referred to as the “second brain”, functions off of the same type of neural network as the central nervous system, suggesting why it plays a significant role in brain function and mental health.

The bidirectional communication is done by immune, endocrine, humoral and neural connections between the gastrointestinal tract and the central nervous system. More research suggests that the gut microorganisms influence the function of the brain by releasing the following chemicals: cytokines, neurotransmitters, neuropeptides, chemokines, endocrine messengers and microbial metabolites such as "short-chain fatty acids, branched chain amino acids, and peptidoglycans”. The intestinal microbiome can then divert these products to the brain via the blood, neuropod cells, nerves, endocrine cells and more to be determined. The products then arrive at important locations in the brain, impacting different metabolic processes. Studies have confirmed communication between the hippocampus, the prefrontal cortex and the amygdala (responsible for emotions and motivation), which acts as a key node in the gut-brain behavioral axis.

While IBS is the only disease confirmed to be directly influenced by the gut microbiome, many disorders (such as anxiety, autism, depression and schizophrenia) have been linked to the gut-brain axis as well. The impact of the axis, and the various ways in which one can influence it, remains a promising research field which could result in future treatments for psychiatric, age-related, neurodegenerative and neurodevelopmental disorders. For example, according to a study from 2017, “probiotics have the ability to restore normal microbial balance, and therefore have a potential role in the treatment and prevention of anxiety and depression”.

The first of the brain–gut interactions shown, was the cephalic phase of digestion, in the release of gastric and pancreatic secretions in response to sensory signals, such as the smell and sight of food. This was first demonstrated by Pavlov through Nobel prize winning research in 1904.

Scientific interest in the field had already led to review in the second half of the 20th century. It was promoted further by a 2004 primary research study showing that germ-free (GF) mice showed an exaggerated HPA axis response to stress compared to non-GF laboratory mice.

As of October 2016, most of the work done on the role of gut microbiota in the gut–brain axis had been conducted in animals, or on characterizing the various neuroactive compounds that gut microbiota can produce. Studies with humans – measuring variations in gut microbiota between people with various psychiatric and neurological conditions or when stressed, or measuring effects of various probiotics (dubbed "psychobiotics" in this context) – had generally been small and were just beginning to be generalized. Whether changes to the gut microbiota are a result of disease, a cause of disease, or both in any number of possible feedback loops in the gut–brain axis, remained unclear.

🔗 Australia 🔗 Organizations 🔗 Men's Issues

Men's sheds or community sheds are non-profit local organisations that provide a space for craftwork and social interaction. The movement originated in Australia around the 1980s as a way to improve the health and wellbeing of older men. However some have expanded their remit to anyone regardless of age or gender, and have similar aims and functions to hackerspaces. There are over 900 located across Australia, with thousands of active members. Men's sheds can also be found in the United Kingdom, Ireland, United States, Canada, Finland, Estonia, New Zealand and Greece.

The slogan for men's sheds is "Shoulder To Shoulder", shortened from "Men don't talk face to face, they talk shoulder to shoulder", adopted after the 2008 Australian Men's Shed Association (AMSA) conference. The users of men's sheds are known as "shedders". In 2014, Professor Barry Golding coined the term "shedagogy" to describe "a distinctive, new way of acknowledging, describing and addressing the way some men prefer to learn informally in shed-like spaces mainly with other men." Sheds as a venue for mentoring other men and Inter-generational mentoring is a growing outcome. Academics are using men's sheds as a research venue and research partner in exploring men's health and social needs.

🔗 Biography 🔗 Military history 🔗 Military history/North American military history 🔗 Mexico 🔗 Military history/Military biography 🔗 Military history/Early Modern warfare 🔗 Military history/Spanish military history 🔗 Mesoamerica 🔗 Spain 🔗 Military history/European military history

Gonzalo Guerrero (also known as Gonzalo Marinero, Gonzalo de Aroca and Gonzalo de Aroza) was a sailor from Palos, Spain who was shipwrecked along the Yucatán Peninsula and was taken as a slave by the local Maya. Earning his freedom, Guerrero became a respected warrior under a Maya lord and raised three of the first mestizo children in Mexico and one of the first mestizo children in the Americas, alongside Miguel Díez de Aux and the children of Caramuru and João Ramalho in Brazil. Little is known of his early life.