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🔗 France 🔗 Ships 🔗 Shipwrecks

Pourquoi Pas? IV (English: Why Not? IV) was the fourth ship built for Jean-Baptiste Charcot, which completed the second Charcot expedition of the Antarctic regions from 1908 to 1910. Charcot died aboard when the ship was wrecked on 16 September 1936, off the coast of Iceland. Of the forty men on board, only one survived.

🔗 United States 🔗 Skepticism 🔗 Alternative medicine 🔗 United States/Louisiana

Hadacol was a patent medicine marketed as a vitamin supplement. Its principal attraction, however, was that it contained 12 percent alcohol (listed on the tonic bottle's label as a "preservative"), which made it quite popular in the dry counties of the southern United States. It was the product of four-term Louisiana State Senator Dudley J. LeBlanc, a Democrat from Erath in Vermilion Parish in southwestern Louisiana. He was not a medical doctor, nor a registered pharmacist, but had a strong talent for self-promotion. Time magazine once described him as "a stem-winding salesman who knows every razzle-dazzle switch in the pitchman's trade".

🔗 Computing 🔗 Computing/Software 🔗 Writing systems 🔗 Typography

A bidirectional text contains both text directionalities, right-to-left (RTL or dextrosinistral) and left-to-right (LTR or sinistrodextral). It generally involves text containing different types of alphabets, but may also refer to boustrophedon, which is changing text direction in each row.

Some writing systems including the Arabic and Hebrew scripts or derived systems such as the Persian, Urdu, and Yiddish scripts, are written in a form known as right-to-left (RTL), in which writing begins at the right-hand side of a page and concludes at the left-hand side. This is different from the left-to-right (LTR) direction used by the dominant Latin script. When LTR text is mixed with RTL in the same paragraph, each type of text is written in its own direction, which is known as bidirectional text. This can get rather complex when multiple levels of quotation are used.

Many computer programs fail to display bidirectional text correctly. For example, the Hebrew name Sarah (שרה) is spelled: sin (ש) (which appears rightmost), then resh (ר), and finally heh (ה) (which should appear leftmost).

Note: Some web browsers may display the Hebrew text in this article in the opposite direction.

🔗 Human rights 🔗 Canada 🔗 LGBT studies 🔗 Law Enforcement 🔗 Discrimination

"Fruit machine" is a term for a device developed in Canada by Frank Robert Wake that was supposed to be able to identify gay men (derogatorily referred to as "fruits"). The subjects were made to view pornography; the device then measured the diameter of the pupils of the eyes (pupillary response test), perspiration, and pulse for a supposed erotic response.

The "fruit machine" was employed in Canada in the 1950s and 1960s during a campaign to eliminate all gay men from the civil service, the Royal Canadian Mounted Police (RCMP), and the military. A substantial number of workers did lose their jobs. Although funding for the "fruit machine" project was cut off in the late 1960s, the investigations continued, and the RCMP collected files on over 9,000 "suspected" gay people.

The chair employed resembled that used by dentists. It had a pulley with a camera going towards the pupils, with a black box located in front of it that displayed pictures. The pictures ranged from the mundane to sexually explicit photos of men and women. It had previously been determined that the pupils would dilate in relation to the amount of interest in the picture per the technique termed 'the pupillary response test'.

People were first led to believe that the machine's purpose was to rate stress. After knowledge of its real purpose became widespread, few people volunteered for it.

🔗 India 🔗 Food and drink 🔗 Food and drink/Foodservice 🔗 Cooperatives 🔗 India/company 🔗 India/food

Indian Coffee House is a restaurant chain in India, run by a series of worker co-operative societies. It has strong presence across India with nearly 400 coffee houses. It has been a hub for Communist, Socialist and liberal movements for generations. Thus it has played a very important role in Geopolitics of India as most successful political movements began from here. Many governments have been formed by the people who regularly visited here.

🔗 Time

Segal's law is an adage that states:

A man with a watch knows what time it is. A man with two watches is never sure.

At surface level, the adage emphasizes the consistency that arises when information comes from a single source and points out the potential pitfalls of having too much conflicting information. However, the underlying message is to question the apparent certainty of anyone who only has one source of information. The man with one watch has no way to identify error or uncertainty.

🔗 Languages 🔗 Anthroponymy

An aptronym, aptonym or euonym is a personal name aptly or peculiarly suited to its owner.

🔗 Video games 🔗 Molecular Biology 🔗 Video games/Sega 🔗 Molecular Biology/Molecular and Cell Biology 🔗 Molecular Biology/Genetics 🔗 Molecular Biology/Cell Signaling

Sonic hedgehog protein (SHH) is encoded for by the SHH gene. The protein is named after the character Sonic the Hedgehog.

This signaling molecule is key in regulating embryonic morphogenesis in all animals. SHH controls organogenesis and the organization of the central nervous system, limbs, digits and many other parts of the body. Sonic hedgehog is a morphogen that patterns the developing embryo using a concentration gradient characterized by the French flag model. This model has a non-uniform distribution of SHH molecules which governs different cell fates according to concentration. Mutations in this gene can cause holoprosencephaly, a failure of splitting in the cerebral hemispheres, as demonstrated in an experiment using SHH knock-out mice in which the forebrain midline failed to develop and instead only a single fused telencephalic vesicle resulted.

Sonic hedgehog still plays a role in differentiation, proliferation, and maintenance of adult tissues. Abnormal activation of SHH signaling in adult tissues has been implicated in various types of cancers including breast, skin, brain, liver, gallbladder and many more.

🔗 United States 🔗 Food and drink 🔗 Food and drink/Foodservice

The Pizza Meter refers to sudden increases of pizza orders from U.S. government offices, such as the White House and The Pentagon, before large events such as the Iraqi invasion of Kuwait, the Panama Invasion, and the Grenada invasion.

On the night of August 1, 1990, the night before the Iraqi invasion of Kuwait, military personnel at The Pentagon came together to discuss issues in the Middle East. According to Frank Meeks, the owner of Washington, D.C.'s Domino's Pizza franchise of 45 restaurants, the CIA ordered a record-breaking 21 pizzas from Domino's that night. Between January 7 to January 16, 1991, the number of pizza deliveries to the Pentagon past 10 p.m reached 101, with another 55 pizzas delivered to the White House on January 16 between 10 p.m. and 2 a.m.

Meeks tied the influx of pizza orders from the Pentagon, White House, and the CIA to oncoming major announcements from the White House, publicizing his observations. Consequently, the public nicknamed the event "The Pizza Meter". Shortly after Meeks' comments were released, government offices no longer ordered from Domino's branches in Washington, opting to buy pizza at separate times or at different pizza joints.

🔗 Psychology 🔗 Neuroscience 🔗 Physiology 🔗 Physiology/neuro

An amygdala hijack refers to a personal, emotional response that is immediate, overwhelming, and out of measure with the actual stimulus because it has triggered a much more significant emotional threat. The term was coined by Daniel Goleman in his 1996 book Emotional Intelligence: Why It Can Matter More Than IQ.