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🔗 Philosophy 🔗 Philosophy/Aesthetics 🔗 Constructed languages

Zaum (Russian: за́умь, lit. 'transrational') are the linguistic experiments in sound symbolism and language creation of Russian Cubo-Futurist poets such as Velimir Khlebnikov and Aleksei Kruchenykh. Zaum is a non-referential phonetic entity with its own ontology. The language consists of neologisms that mean nothing. Zaum is a language organized through phonetic analogy and rhythm. Zaum literature cannot contain any onomatopoeia or psychopathological states.

🔗 Bridges and Tunnels 🔗 Civil engineering

Hobby tunneling (or tunnelling) is tunnel construction as a diversion. Usually, hobby tunnelers dig their tunnels by hand, using little equipment, and some can spend years or even decades to achieve any degree of completion. In some cases tunnels have been dug secretly, and only discovered by chance.

🔗 Companies 🔗 Computing 🔗 United Kingdom

Andrews & Arnold Ltd (also known as AAISP) is an Internet service provider based in Bracknell in the United Kingdom founded in 1997 and launched in 1998, primarily serving businesses and "technical" home users.

In 2009 the company was judged the best niche provider in the Thinkbroadband Customer Service Awards, based on customer ratings and again in 2010.

The company's owner, Adrian Kennard (RevK), stated in a blog post that as of October 2010 the company is "xkcd/806" compliant, referring to xkcd comic number 806. This means that technical support callers who say the code word "shibboleet" will be transferred to a technical support representative who knows at least two programming languages, and presumably can offer more useful advice than a standard tech support script.

Andrews & Arnold provides IPv6 to all customers, for no additional charge.

Andrews & Arnold provides optional bonded multiple-link internet access. This allows multiple links to be used together to vastly increase speed and reliability. Special routers distribute individual IP packets between the available links in such a way that even one single download or upload operation will benefit fully from multiple speed, and it is not necessary to have several users, several running programs or computers to gain the speed benefit. Links can be of different types, each needs only to be a pipe that can carry IP packets. Multiple links can either be used together all the time, or some can be brought up as a back up if other links fail, so-called 'failover', or a combination of the two approaches can be set up.

Andrews & Arnold are strong advocates of not censoring Internet connections. Adrian Kennard has several blog posts discussing why Internet censorship as discussed in the UK is not workable, providing background for AAISP's decision.

🔗 Architecture 🔗 Urban studies and planning

A charrette (American pronunciation: ), often Anglicized to charette or charet and sometimes called a design charrette, is an intense period of design or planning activity.

The word charrette may refer to any collaborative session in which a group of designers draft a solution to a design problem.

While the structure of a charrette varies, depending on the design problem and the individuals in the group, charrettes often take place in multiple sessions in which the group divides into sub-groups. Each sub-group then presents its work to the full group as material for further dialogue. Such charrettes serve as a way of quickly generating a design solution while integrating the aptitudes and interests of a diverse group of people. The general idea of a charrette is to create an innovative atmosphere in which a diverse group of stakeholders can collaborate to "generate visions for the future".

🔗 Lists 🔗 History of Science 🔗 Science

Historians and sociologists have remarked the occurrence, in science, of "multiple independent discovery". Robert K. Merton defined such "multiples" as instances in which similar discoveries are made by scientists working independently of each other. "Sometimes," writes Merton, "the discoveries are simultaneous or almost so; sometimes a scientist will make a new discovery which, unknown to him, somebody else has made years before."

Commonly cited examples of multiple independent discovery are the 17th-century independent formulation of calculus by Isaac Newton, Gottfried Wilhelm Leibniz and others, described by A. Rupert Hall; the 18th-century discovery of oxygen by Carl Wilhelm Scheele, Joseph Priestley, Antoine Lavoisier and others; and the theory of the evolution of species, independently advanced in the 19th century by Charles Darwin and Alfred Russel Wallace.

Multiple independent discovery, however, is not limited to such famous historic instances. Merton believed that it is multiple discoveries, rather than unique ones, that represent the common pattern in science.

Merton contrasted a "multiple" with a "singleton"—a discovery that has been made uniquely by a single scientist or group of scientists working together.

A distinction is drawn between a discovery and an invention, as discussed for example by Bolesław Prus. However, discoveries and inventions are inextricably related, in that discoveries lead to inventions, and inventions facilitate discoveries; and since the same phenomenon of multiplicity occurs in relation to both discoveries and inventions, this article lists both multiple discoveries and multiple inventions.

🔗 Computer science

In distributed computing, a conflict-free replicated data type (CRDT) is a data structure which can be replicated across multiple computers in a network, where the replicas can be updated independently and concurrently without coordination between the replicas, and where it is always mathematically possible to resolve inconsistencies which might result.

The CRDT concept was formally defined in 2011 by Marc Shapiro, Nuno Preguiça, Carlos Baquero and Marek Zawirski. Development was initially motivated by collaborative text editing and mobile computing. CRDTs have also been used in online chat systems, online gambling, and in the SoundCloud audio distribution platform. The NoSQL distributed databases Redis, Riak and Cosmos DB have CRDT data types.

🔗 Viruses 🔗 Biology 🔗 Philosophy 🔗 Philosophy/Contemporary philosophy 🔗 History of Science 🔗 Molecular and Cell Biology 🔗 Philosophy/Ethics 🔗 Genetics 🔗 Evolutionary biology 🔗 Science Policy 🔗 Molecular Biology/Molecular and Cell Biology

HeLa (; also Hela or hela) is an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line. The line was derived from cervical cancer cells taken on February 8, 1951 from Henrietta Lacks, a patient who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which gives rise to its extensive use in scientific research.

The cells from Lacks's cancerous cervical tumor were taken without her knowledge or consent, which was common practice at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would only survive for a few days. Scientists would spend more time trying to keep the cells alive than performing actual research on them. Cells from Lacks' tumor behaved differently. As was custom for Gey's lab assistant, she labeled the culture 'HeLa', the first two letters of the patient's first and last name; this became the name of the cell line.

These were the first human cells grown in a lab that were naturally "immortal", meaning that they do not die after a set number of cell divisions (i.e. cellular senescence). These cells could be used for conducting a multitude of medical experiments—if the cells died, they could simply be discarded and the experiment attempted again on fresh cells from the culture. This represented an enormous boon to medical and biological research, as previously stocks of living cells were limited and took significant effort to culture.

The stable growth of HeLa enabled a researcher at the University of Minnesota hospital to successfully grow polio virus, enabling the development of a vaccine, and by 1952, Jonas Salk developed a vaccine for polio using these cells. To test Salk's new vaccine, the cells were put into mass production in the first-ever cell production factory.

In 1953, HeLa cells were the first human cells successfully cloned and demand for the HeLa cells quickly grew in the nascent biomedical industry. Since the cells' first mass replications, they have been used by scientists in various types of investigations including disease research, gene mapping, effects of toxic substances on organisms, and radiation on humans. Additionally, HeLa cells have been used to test human sensitivity to tape, glue, cosmetics, and many other products.

Scientists have grown an estimated 50 million metric tons of HeLa cells, and there are almost 11,000 patents involving these cells.

The HeLa cell lines are also notorious for invading other cell cultures in laboratory settings. Some have estimated that HeLa cells have contaminated 10–20% of all cell lines currently in use.

🔗 Spaceflight 🔗 Astronomy 🔗 Astronomy/Solar System 🔗 Astronomy/Moon

On April 11, 2019, the Israeli spacecraft Beresheet crashed into the Moon during a failed landing attempt. Its payload included a few thousand tardigrades. Initial reports suggested they could have survived the crash landing. If any of them did survive, they would be the second animal species to reach the Moon, after humans.

We believe the chances of survival for the tardigrades... are extremely high.

🔗 Telecommunications 🔗 Astronomy 🔗 Weather 🔗 Astronomy/Solar System 🔗 Weather/Weather 🔗 Weather/Space weather

The Carrington Event was the most intense geomagnetic storm in recorded history, peaking from 1–2 September 1859 during solar cycle 10. It created strong auroral displays that were reported globally and caused sparking and even fires in multiple telegraph stations. The geomagnetic storm was most likely the result of a coronal mass ejection (CME) from the Sun colliding with Earth's magnetosphere.

The geomagnetic storm was associated with a very bright solar flare on 1 September 1859. It was observed and recorded independently by British astronomers Richard Christopher Carrington and Richard Hodgson—the first records of a solar flare.

A geomagnetic storm of this magnitude occurring today would cause widespread electrical disruptions, blackouts, and damage due to extended outages of the electrical power grid.

🔗 Film 🔗 Television 🔗 BBC 🔗 Film/British cinema

Can't Get You Out of My Head: An Emotional History of the Modern World is a six-part BBC documentary television series created by Adam Curtis. It was released on BBC iPlayer on 11 February 2021.