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πŸ”— Foldit

πŸ”— Video games πŸ”— Molecular Biology πŸ”— Molecular Biology/Molecular and Cell Biology

Foldit is an online puzzle video game about protein folding. It is part of an experimental research project developed by the University of Washington, Center for Game Science, in collaboration with the UW Department of Biochemistry. The objective of Foldit is to fold the structures of selected proteins as perfectly as possible, using tools provided in the game. The highest scoring solutions are analyzed by researchers, who determine whether or not there is a native structural configuration (native state) that can be applied to relevant proteins in the real world. Scientists can then use these solutions to target and eradicate diseases and create biological innovations. A 2010 paper in the science journal Nature credited Foldit's 57,000 players with providing useful results that matched or outperformed algorithmically computed solutions.

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πŸ”— Minivac 601

πŸ”— Computing

Minivac 601 Digital Computer Kit was an electromechanical digital computer system created by information theory pioneer Claude Shannon as an educational toy using digital circuits.

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πŸ”— Magnets cannot exist under classical mechanics

πŸ”— Physics

The Bohr–van Leeuwen theorem states that when statistical mechanics and classical mechanics are applied consistently, the thermal average of the magnetization is always zero. This makes magnetism in solids solely a quantum mechanical effect and means that classical physics cannot account for diamagnetism.

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πŸ”— Hagia Triada Sarcophagus

πŸ”— Death πŸ”— Classical Greece and Rome πŸ”— Archaeology

The Hagia Triada Sarcophagus is a late Minoan 137Β cm (54Β in)-long limestone sarcophagus, dated to about 1400 BC or some decades later, excavated from a chamber tomb at Hagia Triada, Crete in 1903, and now on display in the Heraklion Archaeological Museum ("AMH") in Crete.

Uniquely for such a piece from this date on Crete, it is coated in plaster and painted in fresco on all faces. Otherwise the Minoans (unlike the ancient Egyptians) only used frescoes to decorate palaces and houses for the enjoyment of the living and not in funerary practice. It is the only limestone sarcophagus of its era discovered to date; there are a number of smaller terracotta "ash-chests" (larnax), painted far more crudely, usually in a single colour. It is the only object with a series of narrative scenes of Minoan funerary ritual (later sarcophagi found in the Aegean were decorated with abstract designs and patterns). It was probably originally used for the burial of a prince.

It provides probably the most comprehensive iconography of a pre-Homeric thysiastikis ceremony and one of the best pieces of information on noble burial customs when Crete was under Mycenaean rule, combining features of Minoan and Mycenaean style and subject matter, as well as probable influence from Ancient Egyptian religion.

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πŸ”— Messier Marathon

πŸ”— Astronomy

A Messier marathon is an attempt, usually organized by amateur astronomers, to find as many Messier objects as possible during one night. The Messier catalogue was compiled by French astronomer Charles Messier during the late 18th century and consists of 110 relatively bright deep-sky objects (galaxies, nebulae, and star clusters).

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πŸ”— Pit of despair

πŸ”— Psychology πŸ”— Animal rights

The Pit of despair was a name used by American comparative psychologist Harry Harlow for a device he designed, technically called a vertical chamber apparatus, that he used in experiments on rhesus macaque monkeys at the University of Wisconsin–Madison in the 1970s. The aim of the research was to produce an animal model of clinical depression. Researcher Stephen Suomi described the device as "little more than a stainless-steel trough with sides that sloped to a rounded bottom":

A ​3⁄8Β in. wire mesh floor 1Β in. above the bottom of the chamber allowed waste material to drop through the drain and out of holes drilled in the stainless-steel. The chamber was equipped with a food box and a water-bottle holder, and was covered with a pyramid top [removed in the accompanying photograph], designed to discourage incarcerated subjects from hanging from the upper part of the chamber.

Harlow had already placed newly born monkeys in isolation chambers for up to one year. With the "Pit of despair", he placed monkeys between three months and three years old in the chamber alone, after they had bonded with their mothers, for up to ten weeks. Within a few days, they had stopped moving about and remained huddled in a corner.

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πŸ”— Eastgate Centre, Harare

πŸ”— Shopping Centers πŸ”— Zimbabwe

The Eastgate Centre is a shopping centre and office block in central Harare, Zimbabwe whose architect is Mick Pearce. Designed to be ventilated and cooled by entirely natural means, it was probably the first building in the world to use natural cooling to this level of sophistication. It opened in 1996 on Robert Mugabe Avenue and Second Street, and provides 5,600 mΒ² of retail space, 26,000 mΒ² of office space and parking for 450 cars.

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πŸ”— Nicaraguan Sign Language

πŸ”— Languages πŸ”— Deaf πŸ”— Nicaragua

Nicaraguan Sign Language (ISN; Spanish: Idioma de SeΓ±as de Nicaragua) is a sign language that was largely spontaneously developed by deaf children in a number of schools in western Nicaragua in the 1970s and 1980s. It is of particular interest to the linguists who study it because it offers a unique opportunity to study what they believe to be the birth of a new language.

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πŸ”— Train ferry

πŸ”— Trains πŸ”— Ships

A train ferry is a ship (ferry) designed to carry railway vehicles. Typically, one level of the ship is fitted with railway tracks, and the vessel has a door at the front and/or rear to give access to the wharves. In the United States, train ferries are sometimes referred to as "car ferries", as distinguished from "auto ferries" used to transport automobiles. The wharf (sometimes called a "slip") has a ramp, and a linkspan or "apron", balanced by weights, that connects the railway proper to the ship, allowing for the water level to rise and fall with the tides.

While railway vehicles can be and are shipped on the decks or in the holds of ordinary ships, purpose-built train ferries can be quickly loaded and unloaded by roll-on/roll-off, especially as several vehicles can be loaded or unloaded at once. A train ferry that is a barge is called a car float or rail barge.

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πŸ”— Simulations and games in economics education

πŸ”— Economics πŸ”— Education πŸ”— Game theory πŸ”— Games

A simulation game is "a game that contains a mixture of skill, chance, and strategy to simulate an aspect of reality, such as a stock exchange". Similarly, Finnish author Virpi RuohomΓ€ki states that "a simulation game combines the features of a game (competition, cooperation, rules, participants, roles) with those of a simulation (incorporation of critical features of reality). A game is a simulation game if its rules refer to an empirical model of reality". A properly built simulation game used to teach or learn economics would closely follow the assumptions and rules of the theoretical models within this discipline.

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