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πŸ”— Spirograph

πŸ”— Brands πŸ”— Toys

Spirograph is a geometric drawing device that produces mathematical roulette curves of the variety technically known as hypotrochoids and epitrochoids. The well known toy version was developed by British engineer Denys Fisher and first sold in 1965.

The name has been a registered trademark of Hasbro Inc. since 1998 following purchase of the company that had acquired the Denys Fisher company. The Spirograph brand was relaunched worldwide in 2013, with its original product configurations, by Kahootz Toys.

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πŸ”— 80k dollars almost certainly cures hepatitis C

πŸ”— Medicine πŸ”— Pharmacology

Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir, daclatasvir, or velpatasvir. Cure rates are 30 to 97% depending on the type of hepatitis C virus involved. Safety during pregnancy is unclear; some of the medications used in combination may result in harm to the baby. It is taken by mouth.

Common side effects include feeling tired, headache, nausea, and trouble sleeping. Side effects are generally more common in interferon-containing regimens. Sofosbuvir may reactivate hepatitis B in those who have been previously infected. In combination with ledipasvir, daclatasvir or simeprevir it is not recommended with amiodarone due to the risk of an abnormally slow heartbeat. Sofosbuvir is in the nucleotide analog family of medication and works by blocking the hepatitis C NS5B protein.

Sofosbuvir was discovered in 2007, and approved for medical use in the United States in 2013. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. As of 2016, a 12-week course of treatment costs about US$84,000 in the United States, US$53,000 in the United Kingdom, US$45,000 in Canada, and about US$500 in India. Over 60,000 people were treated with sofosbuvir in its first 30 weeks being sold in the United States.

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πŸ”— Shanti Devi

πŸ”— Biography

Shanti Devi (11 December 1926 – 27 December 1987) was an Indian woman who claimed to remember her past life, and became the subject of reincarnation research. A commission set up by the Indian political leader Mahatma Gandhi supported her claim, while another report by researcher Bal Chand Nahata disputed it. Subsequently, several other researchers interviewed her, and published articles and books about her.

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πŸ”— A*

πŸ”— Computing πŸ”— Computer science πŸ”— Mathematics

A* (pronounced "A-star") is a graph traversal and path search algorithm, which is often used in computer science due to its completeness, optimality, and optimal efficiency. One major practical drawback is its O ( b d ) {\displaystyle O(b^{d})} space complexity, as it stores all generated nodes in memory. Thus, in practical travel-routing systems, it is generally outperformed by algorithms which can pre-process the graph to attain better performance, as well as memory-bounded approaches; however, A* is still the best solution in many cases.

Peter Hart, Nils Nilsson and Bertram Raphael of Stanford Research Institute (now SRI International) first published the algorithm in 1968. It can be seen as an extension of Edsger Dijkstra's 1959 algorithm. A* achieves better performance by using heuristics to guide its search.

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  • "A*" | 2019-08-10 | 50 Upvotes 6 Comments

πŸ”— High Efficiency Image File Format (HEIF/.heic)

πŸ”— Technology πŸ”— Computing πŸ”— Computing/Software πŸ”— Computing/Free and open-source software

High Efficiency Image File Format (HEIF) is a container format for storing individual digital images and image sequences. The standard covers multimedia files that can also include other media streams, such as timed text, audio and video.

HEIF can store images encoded with multiple coding formats, for example both SDR and HDR images. HEVC is an image and video encoding format and the default image codec used with HEIF. HEIF files containing HEVC-encoded images are also known as HEIC files. Such files require less storage space than the equivalent quality JPEG.

HEIF files are a special case of the ISO Base Media File Format (ISOBMFF, ISO/IEC 14496-12), first defined in 2001 as a shared part of MP4 and JPEG 2000. Introduced in 2015, it was developed by the Moving Picture Experts Group (MPEG) and is defined as Part 12 within the MPEG-H media suite (ISO/IEC 23008-12).

HEIF was adopted by Apple in 2017 with the introduction of iOS 11.

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πŸ”— Fan death

πŸ”— Death πŸ”— Korea πŸ”— Skepticism πŸ”— Alternative Views πŸ”— Korea/Korean popular culture working group

Fan death is a widely held belief in Korean culture, where it is thought that running an electric fan in a closed room with unopened or no windows will prove fatal. Despite no concrete evidence to support the concept, belief in fan death persists to this day in Korea, and also to a lesser extent in Japan and Russia.

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πŸ”— Utah Data Center

πŸ”— United States/U.S. Government πŸ”— United States πŸ”— Mass surveillance πŸ”— Espionage πŸ”— Cryptography πŸ”— Cryptography/Computer science πŸ”— United States/Utah

The Utah Data Center (UDC), also known as the Intelligence Community Comprehensive National Cybersecurity Initiative Data Center, is a data storage facility for the United States Intelligence Community that is designed to store data estimated to be on the order of exabytes or larger. Its purpose is to support the Comprehensive National Cybersecurity Initiative (CNCI), though its precise mission is classified. The National Security Agency (NSA) leads operations at the facility as the executive agent for the Director of National Intelligence. It is located at Camp Williams near Bluffdale, Utah, between Utah Lake and Great Salt Lake and was completed in May 2019 at a cost of $1.5 billion.

The Utah Data Center, code-named Bumblehive, is the first Intelligence Community Comprehensive National Cyber-security Initiative (IC CNCI) data center designed to support the US intelligence community. The "massive data repository" is designed to cope with the large increase in digital data that has accompanied the rise of the global internet.

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πŸ”— Sunstone (Medieval)

πŸ”— Physics πŸ”— Astronomy πŸ”— Geology πŸ”— Mythology πŸ”— Iceland πŸ”— Norse history and culture πŸ”— Mythology/Norse mythology

The sunstone (Icelandic: sΓ³larsteinn) is a type of mineral attested in several 13th–14th-century written sources in Iceland, one of which describes its use to locate the Sun in a completely overcast sky. Sunstones are also mentioned in the inventories of several churches and one monastery in 14th–15th-century Iceland and Germany.

A theory exists that the sunstone had polarizing attributes and was used as a navigational instrument by seafarers in the Viking Age. A stone found in 2002 off Alderney, in the wreck of a 16th-century warship, may lend evidence of the existence of sunstones as navigational devices.

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πŸ”— E-Prime: English without the verb 'to be'

πŸ”— Linguistics πŸ”— Linguistics/Applied Linguistics πŸ”— Languages πŸ”— Constructed languages πŸ”— English Language

E-Prime (short for English-Prime or English Prime, sometimes denoted Γ‰ or Eβ€²) is a version of the English language that excludes all forms of the verb to be, including all conjugations, contractions and archaic forms.

Some scholars advocate using E-Prime as a device to clarify thinking and strengthen writing. A number of other scholars have criticized E-Prime's utility.

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πŸ”— The Boston Camera

πŸ”— Maps πŸ”— Photography

The Boston Camera, also known as Pie Face and officially classified as the K-42 Camera Model, was a prototype airborne photo reconnaissance camera manufactured for the United States Air Force by Boston University in 1951 and tested on the Convair B-36 and the C-97 Stratofreighter. The model carried on the first ERB-36D (44-92088) had a 6,096-millimetre (240.0Β in) focal length, which was achieved using a series of lenses and mirrors. The lens had an f/8 stop and used a 1/400 second shutter speed, and could photograph a golf ball from an altitude of 45,000 feet (14,000Β m) feet. The camera used 18-by-36-inch (46 by 91Β cm) negatives. The camera was installed aboard Boeing C-97A 49-2592 (not an "RC-97" or "EC-97" as often widely quoted) which was used operationally by the 7405th Support Squadron based at Wiesbaden, West Germany between 1952 and 1962. It was given to the Air Force Museum in 1964, along with a contact print of a golf ball on a course.

In the words of CIA historian Dino Brugioni:

The lens was designed in 1947 by Dr. James Baker for installation in a camera designed by the Boston University Optical Research Laboratory. The camera weighed about three tons, and eight hundred pounds of lead shot were required to balance it. Supposedly, it was first installed and test-flown in an RB-36, then installed as a left-looking oblique camera in an RC-97. The first photo Arthur Lundahl and I saw from this project was of New York City. The aircraft was seventy-two miles away, and yet we could see people in Central Park.

The Boston Camera was plagued with problems that caused it to vibrate and produce smearing on the newspaper-sized negative, so that photo interpreters would see several smeared frames along with several clear ones. It is currently displayed at the National Museum of the US Air Force in Dayton, Ohio.

From the display placard:

This camera, manufactured for the US Air Force by Boston University in 1951, is the largest aerial camera ever built. It was installed in an RB-36D in 1954 and tested for about a year. Later it was used in a C-97 aircraft flying along the air corridor through communist East Germany to Berlin, but a 10,000 ft (3,000 m) altitude restriction imposed by the communists made the camera less useful than at a higher altitude. It was also used on reconnaissance missions along the borders of Eastern European nations. The camera made an 18 x 36 inch negative and was so powerful a photo interpreter could detect a golf ball from an altitude of 45,000 feet (14,000 m). Dr. James Baker of Harvard University designed the camera.

Technical Notes:

Shutter Speed: 1/400 sec

Weight: 6,500 lbs (3 metric ton) (camera and aircraft mount)

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