Have a deep view into what people are curious about.

🔗 Medicine 🔗 Medicine/Neurology

Type 3 diabetes is a proposed term to describe the interlinked association between type 1 and type 2 diabetes, and Alzheimer's disease. This term is used to look into potential triggers of Alzheimer's disease in people with diabetes.

The proposed progression from diabetes to Alzheimer's disease is inadequately understood; however there are a number of hypotheses describing potential links between the two diseases. The internal mechanism of Insulin resistance and other metabolic risk factors such as hyperglycaemia, caused by oxidative stress and lipid peroxidation are common processes thought to be contributors to the development of Alzheimer's disease in diabetics.

Diagnosis for this disease is different between patients with type 1 and type 2 diabetes. Type 1 diabetes is usually discovered in children and adolescence while type 2 diabetic patients are often diagnosed later in life. While Type 3 diabetes is not a diagnosis in itself, a diagnosis of suspected Alzheimer's disease can be established through observational signs and sometimes with neuroimaging techniques such as Magnetic Resonance Imaging (MRI) to observe abnormalities in diabetic patient's brain tissue.

The techniques used to prevent the disease in patients with diabetes are similar to individuals who do not show signs of the disease. The four pillars of Alzheimer's disease prevention is currently used as a guide for individuals of whom are at risk of developing Alzheimer's disease.

Research into the effectiveness of Glucagon-like Peptide 1 and Melatonin administration to manage the progression of Alzheimer's disease in diabetic patients is currently being conducted to decrease the rate at which Alzheimer's disease progresses.

Labelling Alzheimer's disease as Type 3 Diabetes is generally controversial, and this definition is not a known medical diagnosis. While insulin resistance is a risk factor for the development of Alzheimer's disease and some other dementias, causes of Alzheimer's disease are likely to be much more complex than being explained by insulin factors on their own, and indeed several patients with Alzheimer's disease have normal insulin metabolism.

🔗 Biography 🔗 Mathematics 🔗 Germany 🔗 Physics 🔗 Women scientists 🔗 Biography/science and academia 🔗 Women's History 🔗 Women writers 🔗 Physics/Biographies 🔗 Toys

🔗 Computing 🔗 Computing/Computer hardware

Model M designates a group of computer keyboards designed and manufactured by IBM starting in 1984, and later by Lexmark International, Maxi Switch, and Unicomp. The keyboard's many variations have their own distinct characteristics, with the vast majority having a buckling-spring key design and swappable keycaps. Model M keyboards have been praised by computer enthusiasts and frequent typists due to their durability and consistency, and the tactile and auditory feedback they provide.

The Model M is also regarded as a timeless and durable piece of hardware. Although the computers and computer peripherals produced concurrently with the Model M are considered obsolete, many Model M keyboards are still in use due to their physical durability and the continued validity of their ANSI 101-key and ISO 102-key layouts, through the use of a PS/2 female to USB male adapter with a built-in level converter. Since their original popularity, new generations of writers and computer technicians have rediscovered their unique functionality and aesthetics. The Kentucky-based company Unicomp continues to manufacture and sell Model M keyboards.

🔗 International relations 🔗 History 🔗 Military history 🔗 Africa 🔗 Europe 🔗 Military history/African military history 🔗 British Empire 🔗 Military history/World War II 🔗 Colonialism 🔗 Countering systemic bias

The Scramble for Africa, also called the Partition of Africa or the Conquest of Africa, was the invasion, occupation, division, and colonisation of African territory by European powers during a short period known to historians as the New Imperialism (between 1881 and 1914). In 1870, only 10 percent of Africa was under formal European control; by 1914 this had increased to almost 90 percent of the continent, with only Ethiopia (Abyssinia), the Dervish state (a portion of present-day Somalia) and Liberia still being independent. There were multiple motivations for European colonizers, including desire for valuable resources available throughout the continent, the quest for national prestige, tensions between pairs of European powers, religious missionary zeal and internal African native politics.

The Berlin Conference of 1884, which regulated European colonisation and trade in Africa, is usually referred to as the ultimate point of the Scramble for Africa. Consequent to the political and economic rivalries among the European empires in the last quarter of the 19th century, the partitioning, or splitting up of Africa was how the Europeans avoided warring amongst themselves over Africa. The later years of the 19th century saw the transition from "informal imperialism" by military influence and economic dominance, to direct rule, bringing about colonial imperialism.

🔗 United States/U.S. Government 🔗 United States

"Stellar Wind" (or "Stellarwind") was the code name of a warrantless surveillance program begun under the George W. Bush administration's President's Surveillance Program (PSP). The National Security Agency (NSA) program was approved by President Bush shortly after the September 11, 2001 attacks and was revealed by Thomas Tamm to The New York Times in 2004. Stellar Wind was a prelude to new legal structures that allowed President Bush and President Barack Obama to reproduce each of those programs and expand their reach.

🔗 Computing 🔗 Books

Hacker's Delight is a software algorithm book by Henry S. Warren, Jr. first published in 2002. It presents fast bit-level and low-level arithmetic algorithms for common tasks such as counting bits or improving speed of division by using multiplication.

🔗 Economics 🔗 Futures studies

Pessimism porn is a neologism coined in 2009 during the 2007–2012 global financial crisis to describe the alleged eschatological and survivalist thrill some people derive from predicting, reading and fantasizing about the collapse of civil society through the destruction of the world's economic system.

🔗 Telecommunications

Digital mobile radio (DMR) is a limited open digital mobile radio standard defined in the European Telecommunications Standards Institute (ETSI) Standard TS 102 361 parts 1–4 and used in commercial products around the world. DMR, along with P25 phase II and NXDN are the main competitor technologies in achieving 6.25 kHz equivalent bandwidth using the proprietary AMBE+2 vocoder. DMR and P25 II both use two-slot TDMA in a 12.5 kHz channel, while NXDN uses discrete 6.25 kHz channels using frequency division and TETRA uses a four-slot TDMA in a 25 kHz channel.

DMR was designed with three tiers. DMR tiers I and II (conventional) were first published in 2005, and DMR III (Trunked version) was published in 2012, with manufacturers producing products within a few years of each publication.

The primary goal of the standard is to specify a digital system with low complexity, low cost and interoperability across brands, so radio communications purchasers are not locked into a proprietary solution. In practice, given the current limited scope of the DMR standard, many vendors have introduced proprietary features that make their product offerings non-interoperable with other brands.

🔗 International relations 🔗 Philosophy 🔗 Psychology 🔗 Philosophy/Ethics 🔗 Holidays 🔗 International relations/United Nations

The International Day of Happiness is celebrated worldwide every year on 20 March, and was originally conceptualized and founded in 2006 by Jayme Illien, CEO of the United Nations New World Order project, to advance happiness as a fundamental human right for all human beings, and happytalism, as new economic system, theory, and philosophy, which achieves the United Nations global goals, and the happiness, well-being, and freedom of all life on earth.

The next international day of happiness is March 20, 2021.

The 2020 International Day of Happiness campaign theme is ‘Happiness For All, Together'”. To celebrate, UNIDOHappiness, the UN secretariat for the International Day Of Happiness, is calling on all 7.8 billion people and all 206 nations and territories, to take the "Ten Steps to Global Happiness" challenge and call to action. The ten steps to global happiness are "ten easy steps any individual, organization, or country, can take on the international day of happiness, and throughout happiness week, to celebrate the international day of happiness, while also advancing the happiness, wellbeing, and freedom of all life on earth by 2050, when the United Nations forecasts global population to reach 10 billion". The first step is “Tell Everyone", which is designed "spread the word" to increase global awareness about the very existence of the international day of happiness, and the UN's unanimous recognition of happiness as a human right, as well as happiness as an approach to sustainable economic and human development.

The 2006 origin and inspiration for creating the international day of happiness initially came from founder Jayme Illien's belief that the happiness, wellbeing, and freedom of all life on earth is the ultimate purpose of every human being, nation, and society. Illien developed his vision for global happiness as humanity's ultimate purpose, through a life spent on the frontlines saving orphaned and abandoned children fleeing war, genocide, and extreme poverty, and theorizing about solutions to the human condition, and the great challenges facing humankind, after he himself was abandoned as an orphan, and rescued from a roadside in India in 1980, by missionaries of Mother Teresa, who first named him Adam, and sent him to live in America.

In 2006, Illien first presented the new economic theory, "happytalism", as a new economic system for the 21st century and beyond, to replace old world economic systems (from 5th to 20th century) such as capitalism, communism, socialism, mercantilism, colonialism, feudalism, racism, and sexism, among others - all created more than 150-1000 years ago. In 2006, Illien successfully demonstrated to prominent economists, academics, political scientists, philosophers, presidents, prime ministers, and heads of state, all in a position to advance happytalism as a solution to the great challenges facing humankind, that the new economic theory was the solution to the world's most pressing and greatest human development challenges and opportunities. However, despite Illien's successful proof of happytalism as a new economic system to replace capitalism and other old world, archaic, obsolete economic systems and models, this eminent multidisciplinary group of experts rejected the idea, and refused to further evaluate or consider the new economic theory due to what Illien, and co founder, Ndaba Mandela, believed were "old world and obsolete tyranny of the status quo, entrenched racist and sexist bias, mindset, incompetence, failed intelligence and intellectual vitality, and an archaic, potentially criminal world view that is a gross violation of global ethical norms, and implicit fiduciary responsibility to all humanity, incapable of seeing and doing what is right and necessary to advance humanity forward".

In 2008, in response to the rejection of Illien's concept of "happytalism" as a new economic theory, and convinced of happytalism as the solution to humanity's great challenges and opportunities in the 21st century and beyond, Illien launched the United Nations New World Order project with co founder Ndaba Mandela, grandson of Nelson Mandela, former president of South Africa, who led the revolution and movement that ended apartheid, and "gave birth to a new nation, a new political party, and a new era of democratic governance in South Africa, and the African Continent.". The United Nations New World Order Project launched in 2008 envisioned, among several UN based policy initiatives, the creation of a United Nations sanctioned "international day of happiness", as a global day of awareness that commemorates and recognizes happiness as a human right, and a fundamental, universal human goal, and calls for a new happiness centric human development paradigm which achieves the happiness, wellbeing, and freedom of all life on earth.

Illien drew inspiration for the idea of establishing the international day of happiness from the founders of the United States of America, and authors of the US Declaration of Independence, as well as, the founders of the United Nations, and UN Day, and the authors of the United Nations Charter. Illien believed that an "international day of happiness", established with, and recognized by, a new UN resolution, with the support of all 193 UN member countries, would provide the essential, unique, and broad-based, wide-ranging democratic support, international credibility, and worldwide legal legitimacy, for a new global day of happiness for humanity, which in turn, would enable future generations to eventually, objectively consider the concept of happytalism as a new economic system to solve to the great challenges facing humanity, thereby placing the fate and future of happytalism directly in the hands of the people and future generations.

In 2012, the United Nations General Assembly adopted UN resolution 66 281: International Day of Happiness with the unanimous consensus of all 193 Member States, and the support of then UN Secretary General Ban Ki moon, declaring March 20 as the international day of happiness. Illien chose 20 March for its significance as the March equinox, a universal phenomenon felt simultaneously by all of humankind.

In 2012, the United Nations also hosted the first high level meeting on Happiness and Well-being: Defining A New Economic Paradigm, at which UN Secretary General Ban Ki moon declared:

Later in 2012, then UN Secretary General Ban Ki moon stated in his closing remarks to the 66th session of the UN General Assembly:

On January 22, 2013, then UN Secretary General Ban Ki moon stated in an address to the UN General Assembly:

On March 20, 2013, the first ever international day of happiness was celebrated with the launch of UNIDOHappiness, and the "Ten Steps to Global Happiness" campaign theme, which has since become an annual tradition.

Every 20 March since 2013, the International Day of Happiness is celebrated in 193 UN Member states, 2 observer states, and 11 territories.

On the 3rd ever international day of happiness, UN Secretary Ban Ki moon said,

🔗 Politics 🔗 Anti-war 🔗 Globalization

Global Peace Index (GPI) measures the relative position of nations' and regions' peacefulness. The GPI ranks 172 independent states and territories (99.7 percent of the world's population) according to their levels of peacefulness. In the past decade, the GPI has presented trends of increased global violence and less peacefulness. It also increases the world peace program in the world.

The GPI is a report produced by the Institute for Economics & Peace (IEP) and developed in consultation with an international panel of peace experts from peace institutes and think tanks with data collected and collated by the Economist Intelligence Unit. The Index was first launched in May 2009, with subsequent reports being released annually. In 2015 it ranked 165 countries, up from 121 in 2007. The study was conceived by Australian technology entrepreneur Steve Killelea, and is endorsed by individuals such as former UN Secretary-General Kofi Annan, the Dalai Lama, archbishop Desmond Tutu, former President of Finland and 2008 Nobel Peace Prize laureate Martti Ahtisaari, Nobel laureate Muhammad Yunus, economist Jeffrey Sachs, former president of Ireland Mary Robinson, former Deputy Secretary-General of the United Nations Jan Eliasson and former United States president Jimmy Carter. The updated index is released each year at events in London, Washington, DC; and at the United Nations Secretariat in New York.

The 2019 GPI indicates Iceland, New Zealand, Portugal, Austria and Denmark to be the most peaceful countries and Somalia, Afghanistan, Syria, South Sudan, Yemen, and Iraq to be the least peaceful. Long-term findings of the 2017 GPI include a less peaceful world over the past decade, a 2.14 per cent deterioration in the global level of peace in the past decade, growing inequality in peace between the most and least peaceful countries, a long-term reduction in the GPI Militarization domain, and a widening impact of terrorism, with historically high numbers of people killed in terrorist incidents over the past 10 years.