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🔗 Molecular and Cell Biology 🔗 Neuroscience 🔗 Physiology 🔗 Physiology/cell

Brainbow is a process by which individual neurons in the brain can be distinguished from neighboring neurons using fluorescent proteins. By randomly expressing different ratios of red, green, and blue derivatives of green fluorescent protein in individual neurons, it is possible to flag each neuron with a distinctive color. This process has been a major contribution to the field of connectomics, traditionally known as hodology, which is the study of neural connections in the brain.

The technique was originally developed in 2007 by a team led by Jeff W. Lichtman and Joshua R. Sanes, both at Harvard University. The original technique has recently been adapted for use with other model organisms including Drosophila melanogaster, Caenorhabditis elegans, and Arabidopsis thaliana.

While earlier labeling techniques allowed for the mapping of only a few neurons, this new method allows more than 100 differently mapped neurons to be simultaneously and differentially illuminated in this manner. The resulting images can be quite striking and have won awards in science photography competitions.

🔗 Languages 🔗 Deaf 🔗 Nicaragua

Nicaraguan Sign Language (ISN; Spanish: Idioma de Señas de Nicaragua) is a sign language that was largely spontaneously developed by deaf children in a number of schools in western Nicaragua in the 1970s and 1980s. It is of particular interest to the linguists who study it because it offers a unique opportunity to study what they believe to be the birth of a new language.

🔗 Computer science 🔗 Philosophy 🔗 Psychology 🔗 Philosophy/Social and political philosophy 🔗 Philosophy/Philosophy of science 🔗 Philosophy/Contemporary philosophy 🔗 Philosophy/Philosophy of mind 🔗 Sociology 🔗 Cultural Evolution

Memetics is a theory of the evolution of culture based on Darwinian principles with the meme as the unit of culture. The term "meme" was coined by biologist Richard Dawkins in his 1976 book The Selfish Gene, to illustrate the principle that he later called "Universal Darwinism". All evolutionary processes depend on information being copied, varied, and selected, a process also known as variation with selective retention. The information that is copied is called the replicator, and genes are the replicator for biological evolution. Dawkins proposed that the same process drives cultural evolution, and he called this second replicator the "meme". He gave as examples, tunes, catchphrases, fashions, and technologies. Like genes, memes are selfish replicators and have causal efficacy; in other words, their properties influence their chances of being copied and passed on. Some succeed because they are valuable or useful to their human hosts while others are more like viruses.

Just as genes can work together to form co-adapted gene complexes, so groups of memes acting together form co-adapted meme complexes or memeplexes. Memeplexes include (among many other things) languages, traditions, scientific theories, financial institutions, and religions. Dawkins famously referred to religions as "viruses of the mind".

Among proponents of memetics are psychologist Susan Blackmore, author of The Meme Machine, who argues that when our ancestors began imitating behaviours, they let loose a second replicator and co-evolved to become the "meme machines" that copy, vary, and select memes in culture. Philosopher Daniel Dennett develops memetics extensively, notably in his books Darwin's Dangerous Idea, and From Bacteria to Bach and Back. He describes the units of memes as "the smallest elements that replicate themselves with reliability and fecundity." and claims that "Human consciousness is itself a huge complex of memes." In The Beginning of Infinity, physicist David Deutsch contrasts static societies that depend on anti-rational memes suppressing innovation and creativity, with dynamic societies based on rational memes that encourage enlightenment values, scientific curiosity, and progress.

Criticisms of memetics include claims that memes do not exist, that the analogy with genes is false, that the units cannot be specified, that culture does not evolve through imitation, and that the sources of variation are intelligently designed rather than random. Critics of memetics include biologist Stephen Jay Gould who calls memetics a "meaningless metaphor". Philosopher Dan Sperber argues against memetics as a viable approach to cultural evolution because cultural items are not directly copied or imitated but are reproduced. Anthropologist Robert Boyd and biologist Peter Richerson work within the alternative, and more mainstream, field of cultural evolution theory and gene-culture coevolution. Dual inheritance theory has much in common with memetics but rejects the idea that memes are replicators. From this perspective, memetics is seen as just one of several approaches to cultural evolution and one that is generally considered less useful than the alternatives of gene-culture coevolution or dual inheritance theory. The main difference is that dual inheritance theory ultimately depends on biological advantage to genes, whereas memetics treats memes as a second replicator in its own right. Memetics also extends to the analysis of Internet culture and Internet memes.

🔗 Computing 🔗 Systems 🔗 Computing/Software 🔗 Systems/Software engineering

From its beginnings in the 1960s, writing software has evolved into a profession concerned with how best to maximize the quality of software and of how to create it. Quality can refer to how maintainable software is, to its stability, speed, usability, testability, readability, size, cost, security, and number of flaws or "bugs", as well as to less measurable qualities like elegance, conciseness, and customer satisfaction, among many other attributes. How best to create high quality software is a separate and controversial problem covering software design principles, so-called "best practices" for writing code, as well as broader management issues such as optimal team size, process, how best to deliver software on time and as quickly as possible, work-place "culture", hiring practices, and so forth. All this falls under the broad rubric of software engineering.

🔗 Russia 🔗 History 🔗 Skepticism 🔗 Sociology 🔗 Russia/language and literature of Russia 🔗 Russia/history of Russia

In politics and economics, a Potemkin village is any construction (literal or figurative) whose sole purpose is to provide an external façade to a country which is faring poorly, making people believe that the country is faring better, although statistics and charts would state otherwise. The term comes from stories of a fake portable village built solely to impress Empress Catherine II by her former lover Grigory Potemkin, during her journey to Crimea in 1787. While modern historians claim accounts of this portable village are exaggerated, the original story was that Potemkin erected phony portable settlements along the banks of the Dnieper River in order to impress the Russian Empress; the structures would be disassembled after she passed, and re-assembled farther along her route to be viewed again as if another example. The term is a translation of the Russian: потёмкинские деревни (IPA: /pɐˈtʲɵmkʲɪnskʲɪɪ dʲɪˈrʲɛvnʲɪ/; romanization: potyómkinskiye derévni).

🔗 Computer science 🔗 Mathematics

CORDIC (for COordinate Rotation DIgital Computer), also known as Volder's algorithm, or: Digit-by-digit method Circular CORDIC (Jack E. Volder), Linear CORDIC, Hyperbolic CORDIC (John Stephen Walther), and Generalized Hyperbolic CORDIC (GH CORDIC) (Yuanyong Luo et al.), is a simple and efficient algorithm to calculate trigonometric functions, hyperbolic functions, square roots, multiplications, divisions, and exponentials and logarithms with arbitrary base, typically converging with one digit (or bit) per iteration. CORDIC is therefore also an example of digit-by-digit algorithms. CORDIC and closely related methods known as pseudo-multiplication and pseudo-division or factor combining are commonly used when no hardware multiplier is available (e.g. in simple microcontrollers and FPGAs), as the only operations it requires are additions, subtractions, bitshift and lookup tables. As such, they all belong to the class of shift-and-add algorithms. In computer science, CORDIC is often used to implement floating-point arithmetic when the target platform lacks hardware multiply for cost or space reasons.

🔗 Computing 🔗 Computing/Software 🔗 Computing/Free and open-source software

BRL-CAD is a constructive solid geometry (CSG) solid modeling computer-aided design (CAD) system. It includes an interactive geometry editor, ray tracing support for graphics rendering and geometric analysis, computer network distributed framebuffer support, scripting, image-processing and signal-processing tools. The entire package is distributed in source code and binary form.

Although BRL-CAD can be used for a variety of engineering and graphics applications, the package's primary purpose continues to be the support of ballistic and electromagnetic analyses. In keeping with the Unix philosophy of developing independent tools to perform single, specific tasks and then linking the tools together in a package, BRL-CAD is basically a collection of libraries, tools, and utilities that work together to create, raytrace, and interrogate geometry and manipulate files and data. In contrast to many other 3D modelling applications, BRL-CAD primarily uses CSG rather than boundary representation. This means BRL-CAD can "study physical phenomena such as ballistic penetration and thermal, radiative, neutron, and other types of transport". It does also support boundary representation.

The BRL-CAD libraries are designed primarily for the geometric modeler who also wants to tinker with software and design custom tools. Each library is designed for a specific purpose: creating, editing, and ray tracing geometry, and image handling. The application side of BRL-CAD also offers a number of tools and utilities that are primarily concerned with geometric conversion, interrogation, image format conversion, and command-line-oriented image manipulation.

🔗 Amateur radio

A QSL card is a written confirmation of either a two-way radiocommunication between two amateur radio or citizens band stations; a one-way reception of a signal from an AM radio, FM radio, television or shortwave broadcasting station; or the reception of a two-way radiocommunication by a third party listener. A typical QSL card is the same size and made from the same material as a typical postcard, and most are sent through the mail as such.

QSL card derived its name from the Q code "QSL". A Q code message can stand for a statement or a question (when the code is followed by a question mark). In this case, 'QSL?' (note the question mark) means "Do you confirm receipt of my transmission?" while 'QSL' (without a question mark) means "I confirm receipt of your transmission."

🔗 Psychology 🔗 Neuroscience

The Weber–Fechner law refers to two related hypotheses in the field of psychophysics, known as Weber's law and Fechner's law. Both laws relate to human perception, more specifically the relation between the actual change in a physical stimulus and the perceived change. This includes stimuli to all senses: vision, hearing, taste, touch, and smell.