Have a deep view into what people are curious about.

🔗 Medicine 🔗 Transhumanism 🔗 Neuroscience 🔗 Pharmacology 🔗 Psychoactive and Recreational Drugs

Modafinil, sold under the brand name Provigil among others, is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer, the research on its effectiveness for this use is not conclusive. It is taken by mouth.

Common side effects include headache, anxiety, trouble sleeping, and nausea. Serious side effects may include allergic reactions such as anaphylaxis, Stevens–Johnson syndrome, misuse, and hallucinations. It is unclear if use during pregnancy is safe. The amount of medication used may need to be adjusted in those with kidney or liver problems. It is not recommended in those with an arrhythmia, significant hypertension, or left ventricular hypertrophy. How it works is not entirely clear. One possibility is that it may affect the areas of the brain involved with the sleep cycle.

Modafinil was approved for medical use in the United States in 1998. In the United States it is classified as a schedule IV controlled substance. In the United Kingdom it is a prescription only medication. It is available as a generic medication. In the United Kingdom it costs the NHS about £105.21 a month as of 2018. In the United States the wholesale cost per month is about US$34.20 as of 2018. In 2016, it was the 284th most prescribed medication in the United States, with more than a million prescriptions.

🔗 United States/U.S. Government 🔗 United States 🔗 Technology 🔗 Computing 🔗 Systems 🔗 Cognitive science 🔗 Linguistics 🔗 Computing/Computer science 🔗 Robotics 🔗 Transhumanism 🔗 Linguistics/Applied Linguistics 🔗 Systems/Cybernetics

In the history of artificial intelligence, an AI winter is a period of reduced funding and interest in artificial intelligence research. The term was coined by analogy to the idea of a nuclear winter. The field has experienced several hype cycles, followed by disappointment and criticism, followed by funding cuts, followed by renewed interest years or decades later.

The term first appeared in 1984 as the topic of a public debate at the annual meeting of AAAI (then called the "American Association of Artificial Intelligence"). It is a chain reaction that begins with pessimism in the AI community, followed by pessimism in the press, followed by a severe cutback in funding, followed by the end of serious research. At the meeting, Roger Schank and Marvin Minsky—two leading AI researchers who had survived the "winter" of the 1970s—warned the business community that enthusiasm for AI had spiraled out of control in the 1980s and that disappointment would certainly follow. Three years later, the billion-dollar AI industry began to collapse.

Hype is common in many emerging technologies, such as the railway mania or the dot-com bubble. The AI winter was a result of such hype, due to over-inflated promises by developers, unnaturally high expectations from end-users, and extensive promotion in the media . Despite the rise and fall of AI's reputation, it has continued to develop new and successful technologies. AI researcher Rodney Brooks would complain in 2002 that "there's this stupid myth out there that AI has failed, but AI is around you every second of the day." In 2005, Ray Kurzweil agreed: "Many observers still think that the AI winter was the end of the story and that nothing since has come of the AI field. Yet today many thousands of AI applications are deeply embedded in the infrastructure of every industry."

Enthusiasm and optimism about AI has increased since its low point in the early 1990s. Beginning about 2012, interest in artificial intelligence (and especially the sub-field of machine learning) from the research and corporate communities led to a dramatic increase in funding and investment.

🔗 Engineering

Ephemeralization, a term coined by R. Buckminster Fuller in 1938, is the ability of technological advancement to do "more and more with less and less until eventually you can do everything with nothing," that is, an accelerating increase in the efficiency of achieving the same or more output (products, services, information, etc.) while requiring less input (effort, time, resources, etc.). Fuller's vision was that ephemeralization will result in ever-increasing standards of living for an ever-growing population despite finite resources. The concept has been embraced by those who argue against Malthusian philosophy. The subsequently coined economics term "dematerialization" refers to essentially the same concept as also does eco-economic decoupling.

🔗 Books

The No Asshole Rule: Building a Civilized Workplace and Surviving One That Isn't is a book by Stanford professor Robert I. Sutton. He initially wrote an essay for the Harvard Business Review, published in the breakthrough ideas for 2004. Following the essay, he received more than one thousand emails and testimonies. Among other reasons disclosed in another article published at the Harvard Business Review, these letters led him to write the book, sell more than 115,000 copies, and win the Quill Award for best business book in 2007.

The theme of this book is that workplace bullying worsens morale and productivity. To screen out the toxic staff, it suggests the "no asshole rule". The author insists upon use of the word asshole since other words such as bully or jerk "do not convey the same degree of awfulness". In terms of using the word in the book's title, he said "There's an emotional reaction to a dirty title. You have a choice between being offensive and being ignored."

🔗 Aviation 🔗 Norway 🔗 Arctic 🔗 Sweden

Andrée's Arctic balloon expedition of 1897 was an effort to reach the North Pole in which all three Swedish expedition members – S. A. Andrée, Knut Frænkel, and Nils Strindberg – perished. Andrée, the first Swedish balloonist, proposed a voyage by hydrogen balloon from Svalbard to either Russia or Canada, which was to pass, with luck, straight over the North Pole on the way. The scheme was received with patriotic enthusiasm in Sweden, a northern nation that had fallen behind in the race for the North Pole.

Andrée ignored many early signs of the dangers associated with his balloon plan. Being able to steer the balloon to some extent was essential for a safe journey, but there was much evidence that the drag-rope steering technique he had invented was ineffective. Worse, the polar balloon Örnen (Eagle) was delivered directly to Svalbard from its manufacturer in Paris without being tested. When measurements showed it to be leaking more than expected, Andrée failed to acknowledge the risk.

After Andrée, Strindberg, and Frænkel lifted off from Svalbard in July 1897, the balloon lost hydrogen quickly and crashed on the pack ice after only two days. The explorers were unhurt but faced a grueling trek back south across the drifting icescape. Inadequately clothed, equipped, and prepared, and shocked by the difficulty of the terrain, they did not make it to safety. As the Arctic winter closed in on them in October, the group ended up exhausted on the deserted Kvitøya (White Island) in Svalbard and died there. For 33 years the fate of the expedition remained one of the unsolved riddles of the Arctic. The chance discovery in 1930 of the expedition's last camp created a media sensation in Sweden, where the dead men had been mourned and idolized.

Andrée's motives and mindset have been the subject of extensive fictional and historical discussion, particularly inspired by his apparent foolhardiness. An early example is Per Olof Sundman's fictionalized bestseller novel of 1967, The Flight of the Eagle, which portrays Andrée as weak and cynical, at the mercy of his sponsors and the media. Modern writers have been generally critical of Andrée.

Noblesse oblige (; French: [nɔblɛs ɔbliʒ]) is a French expression used in English meaning that nobility extends beyond mere entitlements and requires the person who holds such a status to fulfill social responsibilities. For example, a primary obligation of a nobleman could include generosity towards those around him.

The Oxford English Dictionary states that the term suggests "noble ancestry constrains to honourable behaviour; privilege entails responsibility."

The Dictionnaire de l'Académie française defines it thus:

1. Whoever claims to be noble must conduct himself nobly.
2. (Figuratively) One must act in a fashion that conforms to one's position and privileges with which one has been born, bestowed and/or has earned.

🔗 Psychology

A cognitive distortion is an exaggerated or irrational thought pattern involved in the onset and perpetuation of psychopathological states, especially those more influenced by psychosocial factors, such as depression and anxiety. Psychiatrist Aaron T. Beck laid the groundwork for the study of these distortions, and his student David D. Burns continued research on the topic. Burns, in Feeling Good the new Mood Therapy , described personal and professional anecdotes related to cognitive distortions and their elimination.

Cognitive distortions are thoughts that cause individuals to perceive reality inaccurately. According to the cognitive model of Beck, a negative outlook on reality, sometimes called negative schemas (or schemata), is a factor in symptoms of emotional dysfunction and poorer subjective well-being. Specifically, negative thinking patterns reinforce negative emotions and thoughts. During difficult circumstances, these distorted thoughts can contribute to an overall negative outlook on the world and a depressive or anxious mental state.

Challenging and changing cognitive distortions is a key element of cognitive behavioral therapy (CBT).

🔗 Physics

In physics, the fourth, fifth and sixth derivatives of position are defined as derivatives of the position vector with respect to time – with the first, second, and third derivatives being velocity, acceleration, and jerk, respectively. Unlike the first three derivatives, the higher-order derivatives are less common, thus their names are not as standardized, though the concept of a minimum snap trajectory has been used in robotics and is implemented in MATLAB.

The fourth derivative is often referred to as snap or jounce. The name "snap" for the fourth derivative led to crackle and pop for the fifth and sixth derivatives respectively, inspired by the Rice Krispies mascots Snap, Crackle, and Pop. These terms are occasionally used, though "sometimes somewhat facetiously".

🔗 Companies 🔗 Apple Inc. 🔗 Business 🔗 Nevada

Braeburn Capital Inc. is an asset management company based in Reno, Nevada and a subsidiary of Apple Inc. Its offices are located at 6900 S. McCarran Boulevard in Reno.

🔗 Philosophy 🔗 Classical Greece and Rome 🔗 Greece 🔗 Philosophy/Ancient philosophy 🔗 Philosophy/Epistemology

Pyrrhonism is an Ancient Greek school of philosophical skepticism which rejects dogma and advocates the suspension of judgement over the truth of all beliefs. It was founded by Aenesidemus in the first century BCE, and said to have been inspired by the teachings of Pyrrho and Timon of Phlius in the fourth century BCE. Pyrrhonism is best known today through the surviving works of Sextus Empiricus, writing in the late second century or early third century CE. The publication of Sextus' works in the Renaissance ignited a revival of interest in Skepticism and played a major role in Reformation thought and the development of early modern philosophy.