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🔗 Economics 🔗 Law Enforcement

The iron law of prohibition is a term coined by Richard Cowan in 1986 which posits that as law enforcement becomes more intense, the potency of prohibited substances increases. Cowan put it this way: "the harder the enforcement, the harder the drugs."

This law is an application of the Alchian–Allen effect; Libertarian judge James P. Gray calls the law the "cardinal rule of prohibition", and notes that is a powerful argument for the legalization of drugs. It is based on the premise that when drugs or alcohol are prohibited, they will be produced in black markets in more concentrated and powerful forms, because these more potent forms offer better efficiency in the business model—they take up less space in storage, less weight in transportation, and they sell for more money. Economist Mark Thornton writes that the iron law of prohibition undermines the argument in favor of prohibition, because the higher potency forms are less safe for the consumer.

🔗 Mathematics 🔗 Physics

The Fresnel integrals S(x) and C(x) are two transcendental functions named after Augustin-Jean Fresnel that are used in optics and are closely related to the error function (erf). They arise in the description of near-field Fresnel diffraction phenomena and are defined through the following integral representations:

The simultaneous parametric plot of S(x) and C(x) is the Euler spiral (also known as the Cornu spiral or clothoid).

🔗 Electronics 🔗 Electrical engineering

A thyratron is a type of gas-filled tube used as a high-power electrical switch and controlled rectifier. Thyratrons can handle much greater currents than similar hard-vacuum tubes. Electron multiplication occurs when the gas becomes ionized, producing a phenomenon known as a Townsend discharge. Gases used include mercury vapor, xenon, neon, and (in special high-voltage applications or applications requiring very short switching times) hydrogen. Unlike a vacuum tube (valve), a thyratron cannot be used to amplify signals linearly.

In the 1920s, thyratrons were derived from early vacuum tubes such as the UV-200, which contained a small amount of argon gas to increase its sensitivity as a radio signal detector, and the German LRS relay tube, which also contained argon gas. Gas rectifiers, which predated vacuum tubes, such as the argon-filled General Electric "Tungar bulb" and the Cooper-Hewitt mercury-pool rectifier, also provided an influence. Irving Langmuir and G. S. Meikle of GE are usually cited as the first investigators to study controlled rectification in gas tubes, about 1914. The first commercial thyratrons appeared circa 1928.

The term "thyratron" is derived from Ancient Greek "θύρα" ("thyra"), meaning "door" or "valve". The term "thyristor" was further derived from a combination of "thyratron" and "transistor". Since the 1960s thyristors have replaced thyratrons in most low- and medium-power applications.

🔗 Ecology

The Lotka–Volterra equations, also known as the Lotka–Volterra predator–prey model, are a pair of first-order nonlinear differential equations, frequently used to describe the dynamics of biological systems in which two species interact, one as a predator and the other as prey. The populations change through time according to the pair of equations: $${\displaystyle {\begin{aligned}{\frac {dx}{dt}}&=\alpha x-\beta xy,\\{\frac {dy}{dt}}&=-\gamma y+\delta xy,\end{aligned}}}$$

where

• the variable x is the population density of prey (for example, the number of rabbits per square kilometre);
• the variable y is the population density of some predator (for example, the number of foxes per square kilometre);
• ${\displaystyle {\tfrac {dy}{dt}}}$ and ${\displaystyle {\tfrac {dx}{dt}}}$ represent the instantaneous growth rates of the two populations;
• t represents time;
• The prey's parameters, α and β, describe, respectively, the maximum prey per capita growth rate, and the effect of the presence of predators on the prey death rate.
• The predator's parameters, γ, δ, respectively describe the predator's per capita death rate, and the effect of the presence of prey on the predator's growth rate.
• All parameters are positive and real.

The solution of the differential equations is deterministic and continuous. This, in turn, implies that the generations of both the predator and prey are continually overlapping.

The Lotka–Volterra system of equations is an example of a Kolmogorov population model (not to be confused with the better known Kolmogorov equations), which is a more general framework that can model the dynamics of ecological systems with predator–prey interactions, competition, disease, and mutualism.

🔗 Internet

Web Environment Integrity (WEI) is a controversial API proposal currently being developed for Google Chrome. As of August 2023, a Web Environment Integrity prototype exists in Chromium, but has not shipped in any browser.

🔗 Biography 🔗 China/Chinese history 🔗 Italy 🔗 China

Katarina Vilioni (died 1342) was one of the first Europeans known to have resided in China. She was apparently a member of a Genoese trading family that lived in Yangzhou during the mid-14th century.

Vilioni is known through her tombstone, which was rediscovered at Yangzhou in 1951. It suggests that Vilioni died in 1342 and was the daughter of a man named Domenico Vilioni.

🔗 Biography 🔗 Canada 🔗 Athletics 🔗 Running 🔗 Biography/sports and games

Terrance Stanley Fox (July 28, 1958 – June 28, 1981) was a Canadian athlete, humanitarian, and cancer research activist. In 1980, with one leg having been amputated due to cancer, he embarked on an east to west cross-Canada run to raise money and awareness for cancer research. Although the spread of his cancer eventually forced him to end his quest after 143 days and 5,373 kilometres (3,339 mi), and ultimately cost him his life, his efforts resulted in a lasting, worldwide legacy. The annual Terry Fox Run, first held in 1981, has grown to involve millions of participants in over 60 countries and is now the world's largest one-day fundraiser for cancer research; over C$750 million has been raised in his name, as of January 2018.

Fox was a distance runner and basketball player for his Port Coquitlam high school, now named after him, and Simon Fraser University. His right leg was amputated in 1977 after he was diagnosed with osteosarcoma, though he continued to run using an artificial leg. He also played wheelchair basketball in Vancouver, winning three national championships.

In 1980, he began the Marathon of Hope, a cross-country run to raise money for cancer research. He hoped to raise one dollar from each of Canada's 24 million people. He began with little fanfare from St John's, Newfoundland and Labrador, in April and ran the equivalent of a full marathon every day. Fox had become a national star by the time he reached Ontario; he made numerous public appearances with businessmen, athletes, and politicians in his efforts to raise money. He was forced to end his run outside Thunder Bay when the cancer spread to his lungs. His hopes of overcoming the disease and completing his marathon ended when he died nine months later.

In addition to being the youngest person ever named a Companion of the Order of Canada, Fox won the 1980 Lou Marsh Award as the nation's top sportsman and was named Canada's Newsmaker of the Year in both 1980 and 1981. Considered a national hero, he has had many buildings, statues, roads, and parks named in his honour across the country.

Meta is a company performing big data analysis of scientific literature. Company is headquartered in Redwood City, California (formerly Toronto, Ontario, Canada) and operates Meta Science, a literature discovery platform. The company was acquired by the Chan Zuckerberg Initiative in 2017.

🔗 Video games 🔗 Molecular Biology 🔗 Molecular Biology/Molecular and Cell Biology

Foldit is an online puzzle video game about protein folding. It is part of an experimental research project developed by the University of Washington, Center for Game Science, in collaboration with the UW Department of Biochemistry. The objective of Foldit is to fold the structures of selected proteins as perfectly as possible, using tools provided in the game. The highest scoring solutions are analyzed by researchers, who determine whether or not there is a native structural configuration (native state) that can be applied to relevant proteins in the real world. Scientists can then use these solutions to target and eradicate diseases and create biological innovations. A 2010 paper in the science journal Nature credited Foldit's 57,000 players with providing useful results that matched or outperformed algorithmically computed solutions.