Have a deep view into what people are curious about.

🔗 Psychology 🔗 Disability

Working memory training is intended to improve a person's working memory. Working memory is a central intellectual faculty, linked to IQ, ageing, and mental health. It has been claimed that working memory training programs are effective means, both for treating specific medical conditions associated with working memory deficit, and for general increase in cognitive capacity among healthy neurotypical adults.

Individual studies of the topic show different, and sometime contradictory, results, and as one meta study puts it, asking the question “Does cognitive training improve intelligence?” is as inappropriate as asking “Does medicine cure disease?”, since none of them specify which particular intervention (which medicine or working memory training program) is being evaluated, for alleviating which condition is it applied (ADHD, stroke, general cognitive improvement etc.), and under what circumstances is it administered (selection criteria, adherence rate, outcome variables etc.).

In an influential metastudy from 2012, highly critical to cognitive training, analysed 23 studies with 30 group comparisons, and concluded that clinical memory training programs produce reliable short-term improvements in working memory skills in children and adults with ADHD, but also that there is no evidence that such effects can be maintained long-term without additional follow-up training. Three years later, another metastudy reached the opposite conclusion, that working memory training does have consistent and useful effects, not just on the type of working memory tests that are practiced, but also at other non-trained tasks and everyday life. Since then, a range of additional clinical experiments have been completed, with larger sample sizes, clearly defined control groups, and more uniform treatment of outcome variables. While the evidence is still far from unanimous, there are several experimental studies of working memory training that have shown beneficial effects for people with ADHD, those who have suffered stroke or traumatic brain injury, children who have undergone cancer treatment, as well as for normally developing children.

🔗 Biography 🔗 Portugal

Álvaro de Campos (Portuguese pronunciation: [ˈalvɐɾu ðɨ ˈkɐ̃puʃ]; October 15, 1890 – November 30, 1935) was one of the poet Fernando Pessoa's various heteronyms, widely known by his powerful and wrathful writing style. According to his author, this alter ego was born in Tavira, Portugal, studied mechanical engineering and finally graduated in ship engineering in Glasgow. After a journey in Ireland, Campos sailed to the Orient and wrote his poem "Opiario" in the Suez Canal "onboard". He worked in 'Barrow-on-Furness' (sic) (of which Pessoa wrote a poem about) and Newcastle-on-Tyne (1922). Unemployed, Campos returned to Lisbon in 1926 (he wrote then the poem "Lisbon Revisited"), where he lived ever since. He was born in October, 1890, but Pessoa didn't put an end to the life of Campos, so he would have survived his author who died in November, 1935. Campos' works may be split in three phases: the decadent phase, the futuristic phase and the decadent (sad) phase. He chose Whitman and Marinetti as masters, showing some similarities with their works, mainly in the second phase: hymns like "Ode Triunfal", "Ode Marítima", and "Ultimatum" praise the power of the rising technology, the strength of the machines, the dark side of the industrial civilization, and an enigmatic love for the machines. The first phase (marked by the poem Opiário) shared some of its pessimism with Pessoa's friend Mário de Sá-Carneiro, one of his co-workers in Orpheu magazine. In the last phase, Pessoa drops the mask, and reveals through Campos all the emptiness and nostalgy that grew during his last years of life. In his last phase Campos wrote the poems "Lisbon Revisited" and the well-known "Tobaco Shop".

"I always want to be the thing I feel kinship with...
To feel everything in every way,
To hold all opinions,
To be sincere contradicting oneself every minute..."

🔗 Economics 🔗 Sociology

Commons-based peer production (CBPP) is a term coined by Harvard Law School professor Yochai Benkler. It describes a model of socio-economic production in which large numbers of people work cooperatively; usually over the Internet. Commons-based projects generally have less rigid hierarchical structures than those under more traditional business models. Often—but not always—commons-based projects are designed without a need for financial compensation for contributors. For example, sharing of STL (file format) design files for objects freely on the internet enables anyone with a 3-D printer to digitally replicate the object saving the prosumer significant money.

The term is often used interchangeably with the term social production.

🔗 Business 🔗 Engineering

Ishikawa diagrams (also called fishbone diagrams, herringbone diagrams, cause-and-effect diagrams, or Fishikawa) are causal diagrams created by Kaoru Ishikawa that show the causes of a specific event.

Common uses of the Ishikawa diagram are product design and quality defect prevention to identify potential factors causing an overall effect. Each cause or reason for imperfection is a source of variation. Causes are usually grouped into major categories to identify and classify these sources of variation.

🔗 Journalism 🔗 Scientology 🔗 Crime and Criminal Biography

Operation Freakout, also known as Operation PC Freakout, was a Church of Scientology covert plan intended to have the U.S. author and journalist Paulette Cooper imprisoned or committed to a psychiatric hospital. The plan, undertaken in 1976 following years of church-initiated lawsuits and covert harassment, was meant to eliminate the perceived threat that Cooper posed to the church and obtain revenge for her publication in 1971 of a highly critical book, The Scandal of Scientology. The Federal Bureau of Investigation discovered documentary evidence of the plot and the preceding campaign of harassment during an investigation into the Church of Scientology in 1977, eventually leading to the church compensating Cooper in an out-of-court settlement.

🔗 Biography 🔗 China 🔗 Biography/science and academia

Yuan Longping (Chinese: 袁隆平; September 7, 1930 – May 22, 2021) was a Chinese agronomist, member of the Chinese Academy of Engineering, known for developing the first hybrid rice varieties in the 1970s.

Hybrid rice has since been grown in dozens of countries in Africa, America, and Asia—providing a robust food source in areas with a high risk of famine. For his contributions, Yuan is always called the "Father of Hybrid Rice" by the Chinese media. On May 22, 2021, Yuan Longping died of multiple organ failure at the age of 90.

🔗 Linguistics

🔗 Plants 🔗 Psychoactive and Recreational Drugs 🔗 Altered States of Consciousness 🔗 South America

Ayahuasca is a South American (pan-Amazonian) psychoactive brew used both socially and as ceremonial spiritual medicine among the indigenous peoples of the Amazon basin. It is a psychedelic and entheogenic brew commonly made out of the Banisteriopsis caapi vine, the Psychotria viridis shrub or a substitute, and possibly other ingredients. A chemically similar preparation, sometimes called "pharmahuasca", can be prepared using N,N-Dimethyltryptamine (DMT) and a pharmaceutical monoamine oxidase inhibitor (MAOI), such as isocarboxazid. B. caapi contains several alkaloids that act as MAOIs, which are required for DMT to be orally active. Ayahuasca is prepared in a tea that, when consumed, causes an altered state of consciousness or "high", including visual hallucinations and altered perceptions of reality.

The other required ingredient is a plant that contains the primary psychoactive, DMT. This is usually the shrub P. viridis, but Diplopterys cabrerana may be used as a substitute. Other plant ingredients often or occasionally used in the production of ayahuasca include Justicia pectoralis, one of the Brugmansia (especially Brugmansia insignis and Brugmansia versicolor, or a hybrid breed) or Datura species, and mapacho (Nicotiana rustica).

🔗 Medicine 🔗 Chemicals 🔗 Medicine/Neurology 🔗 Pharmacology 🔗 Medicine/Psychiatry 🔗 Epilepsy

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955 and was made available in 1960 by Hoffmann–La Roche, who soon followed with diazepam (Valium) in 1963. By 1977, benzodiazepines were the most prescribed medications globally; the introduction of selective serotonin reuptake inhibitors (SSRIs), among other factors, decreased rates of prescription, but they remain frequently used worldwide.

Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. These properties make benzodiazepines useful in treating anxiety, panic disorder, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as short, intermediate, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.

Benzodiazepines are generally viewed as safe and effective for short-term use—about two to four weeks—although cognitive impairment and paradoxical effects such as aggression or behavioral disinhibition can occur. A minority of people have paradoxical reactions after taking benzodiazepines such as worsened agitation or panic. Benzodiazepines are associated with an increased risk of suicide due to aggression, impulsivity, and negative withdrawal effects. Long-term use is controversial because of concerns about decreasing effectiveness, physical dependence, benzodiazepine withdrawal syndrome, and an increased risk of dementia and cancer. The elderly are at an increased risk of both short- and long-term adverse effects, and as a result, all benzodiazepines are listed in the Beers List of inappropriate medications for older adults. There is controversy concerning the safety of benzodiazepines in pregnancy. While they are not major teratogens, uncertainty remains as to whether they cause cleft palate in a small number of babies and whether neurobehavioural effects occur as a result of prenatal exposure; they are known to cause withdrawal symptoms in the newborn.

Taken in overdose, benzodiazepines can cause dangerous deep unconsciousness, but they are less toxic than their predecessors, the barbiturates, and death rarely results when a benzodiazepine is the only drug taken. Combined with other central nervous system (CNS) depressants such as alcohol and opioids, the potential for toxicity and fatal overdose increases significantly. Benzodiazepines are commonly used recreationally and also often taken in combination with other addictive substances, and are controlled in most countries.

🔗 Biography 🔗 New York (state) 🔗 New York (state)/Columbia University

Randolph Silliman Bourne (; May 30, 1886 – December 22, 1918) was a progressive writer and intellectual born in Bloomfield, New Jersey, and a graduate of Columbia University. He is considered to be a spokesman for the young radicals living during World War I. His articles appeared in journals including The Seven Arts and The New Republic. Bourne is best known for his essays, especially his unfinished work "The State," discovered after he died. From this essay (which was published posthumously and included in Untimely Papers) comes the phrase "war is the health of the state" which laments the success of governments in arrogating authority and resources during conflicts.