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Augusta Ada King, Countess of Lovelace (née Byron; 10 December 1815 – 27 November 1852) was an English mathematician and writer, chiefly known for her work on Charles Babbage's proposed mechanical general-purpose computer, the Analytical Engine. She was the first to recognise that the machine had applications beyond pure calculation, and published the first algorithm intended to be carried out by such a machine. As a result, she is sometimes regarded as the first to recognise the full potential of a "computing machine" and one of the first computer programmers.

Augusta Byron was the only legitimate child of poet Lord Byron and his wife Lady Byron. All of Byron's other children were born out of wedlock to other women. Byron separated from his wife a month after Ada was born and left England forever four months later. He commemorated the parting in a poem that begins, "Is thy face like thy mother's my fair child! ADA! sole daughter of my house and heart?". He died of disease in the Greek War of Independence when Ada was eight years old. Her mother remained bitter and promoted Ada's interest in mathematics and logic in an effort to prevent her from developing her father's perceived insanity. Despite this, Ada remained interested in Byron, naming her two sons Byron and Gordon. Upon her eventual death, she was buried next to him at her request. Although often ill in her childhood, Ada pursued her studies assiduously. She married William King in 1835. King was made Earl of Lovelace in 1838, Ada thereby becoming Countess of Lovelace.

Her educational and social exploits brought her into contact with scientists such as Andrew Crosse, Charles Babbage, Sir David Brewster, Charles Wheatstone, Michael Faraday and the author Charles Dickens, contacts which she used to further her education. Ada described her approach as "poetical science" and herself as an "Analyst (& Metaphysician)".

When she was a teenager, her mathematical talents led her to a long working relationship and friendship with fellow British mathematician Charles Babbage, who is known as "the father of computers". She was in particular interested in Babbage's work on the Analytical Engine. Lovelace first met him in June 1833, through their mutual friend, and her private tutor, Mary Somerville.

Between 1842 and 1843, Ada translated an article by Italian military engineer Luigi Menabrea on the calculating engine, supplementing it with an elaborate set of notes, simply called Notes. These notes contain what many consider to be the first computer program—that is, an algorithm designed to be carried out by a machine. Other historians reject this perspective and point out that Babbage's personal notes from the years 1836/1837 contain the first programs for the engine. Lovelace's notes are important in the early history of computers. She also developed a vision of the capability of computers to go beyond mere calculating or number-crunching, while many others, including Babbage himself, focused only on those capabilities. Her mindset of "poetical science" led her to ask questions about the Analytical Engine (as shown in her notes) examining how individuals and society relate to technology as a collaborative tool.

She died of uterine cancer in 1852 at the age of 36.

Cecilia Helena Payne-Gaposchkin (née Payne; (1900-05-10)May 10, 1900 – (1979-12-07)December 7, 1979) was a British-born American astronomer and astrophysicist who proposed in her 1925 doctoral thesis that stars were composed primarily of hydrogen and helium. Her groundbreaking conclusion was initially rejected because it contradicted the scientific wisdom of the time, which held that there were no significant elemental differences between the Sun and Earth. Independent observations eventually proved she was actually correct

Donna Theo Strickland, (born 27 May 1959) is a Canadian optical physicist and pioneer in the field of pulsed lasers. She was awarded the Nobel Prize in Physics in 2018, together with Gérard Mourou, for the invention of chirped pulse amplification. She is a professor at the University of Waterloo.

She served as fellow, vice president, and president of The Optical Society, and is currently chair of their Presidential Advisory Committee. In 2018, she was listed as one of BBC's 100 Women.

Grace Brewster Murray Hopper (née Murray December 9, 1906 – January 1, 1992) was an American computer scientist and United States Navy rear admiral. One of the first programmers of the Harvard Mark I computer, she was a pioneer of computer programming who invented one of the first linkers. She popularized the idea of machine-independent programming languages, which led to the development of COBOL, an early high-level programming language still in use today.

Prior to joining the Navy, Hopper earned a Ph.D. in mathematics from Yale University and was a professor of mathematics at Vassar College. Hopper attempted to enlist in the Navy during World War II but was rejected because she was 34 years old. She instead joined the Navy Reserves. Hopper began her computing career in 1944 when she worked on the Harvard Mark I team led by Howard H. Aiken. In 1949, she joined the Eckert–Mauchly Computer Corporation and was part of the team that developed the UNIVAC I computer. At Eckert–Mauchly she began developing the compiler. She believed that a programming language based on English was possible. Her compiler converted English terms into machine code understood by computers. By 1952, Hopper had finished her program linker (originally called a compiler), which was written for the A-0 System. During her wartime service, she co-authored three papers based on her work on the Harvard Mark 1.

In 1954, Eckert–Mauchly chose Hopper to lead their department for automatic programming, and she led the release of some of the first compiled languages like FLOW-MATIC. In 1959, she participated in the CODASYL consortium, which consulted Hopper to guide them in creating a machine-independent programming language. This led to the COBOL language, which was inspired by her idea of a language being based on English words. In 1966, she retired from the Naval Reserve, but in 1967 the Navy recalled her to active duty. She retired from the Navy in 1986 and found work as a consultant for the Digital Equipment Corporation, sharing her computing experiences.

The U.S. Navy Arleigh Burke-class guided-missile destroyer USS Hopper was named for her, as was the Cray XE6 "Hopper" supercomputer at NERSC. During her lifetime, Hopper was awarded 40 honorary degrees from universities across the world. A college at Yale University was renamed in her honor. In 1991, she received the National Medal of Technology. On November 22, 2016, she was posthumously awarded the Presidential Medal of Freedom by President Barack Obama.

Hedy Lamarr (), born Hedwig Eva Maria Kiesler (November 9, 1914 – January 19, 2000), was an Austrian-born American actress, inventor and film producer. She was part of 30 films in an acting career spanning 28 years, and co-invented an early version of frequency-hopping spread spectrum.

After a brief early film career in Czechoslovakia, including the controversial Ecstasy (1933), she fled from her husband, a wealthy Austrian ammunition manufacturer, and secretly moved to Paris. Traveling to London, she met Louis B. Mayer, head of Metro-Goldwyn-Mayer (MGM) studio, who offered her a movie contract in Hollywood, where he began promoting her as the "world's most beautiful woman".

She became a star with her performance in Algiers (1938), her first film made in the United States. Her MGM films include Lady of the Tropics (1939), Boom Town (1940), H.M. Pulham, Esq. (1941), and White Cargo (1942). Dismayed with her MGM contract, Lamarr co-founded a new production studio and starred in its films including The Strange Woman (1946), and Dishonored Lady (1947). Her greatest success was as Delilah in Cecil B. DeMille's Samson and Delilah (1949). She also acted on television before the release of her final film, The Female Animal (1958). She was honored with a star on the Hollywood Walk of Fame in 1960.

At the beginning of World War II, Lamarr and composer George Antheil developed a radio guidance system for Allied torpedoes, intended to use frequency-hopping spread spectrum technology to defeat the threat of jamming by the Axis powers. She also helped to improve aviation designs for Howard Hughes while they dated during the war. Although the US Navy did not adopt Lamarr and Antheil's invention until 1957, various spread-spectrum techniques are incorporated into Bluetooth technology and are similar to methods used in legacy versions of Wi-Fi. Recognition of the value of their work resulted in the pair being posthumously inducted into the National Inventors Hall of Fame in 2014.

Kateryna Lohvynivna Yushchenko (Ukrainian: Катерина Логвинівна Ющенко, Russian: Екатерина Логвиновна Ющенко, December 8, 1919, Chyhyryn - died August 15, 2001) was a Ukrainian computer and information research scientist, corresponding member of USSR Academy of Sciences (1976), and member of The International Academy of Computer Science. She developed one of the world's first high-level languages with indirect address in programming, called the Address programming language. Over the period of her academic career, Yushchenko supervised 45 Ph.D students. Further professional achievements include Yushchenko being awarded two USSR State Prizes, The USSR Council of Ministers Prize, The Academician Glushkov Prize, and The Order of Princess Olga. Yushchenko was the first woman in the USSR to become a Doctor of Physical and Mathematical Sciences in programming.

Maryam Mirzakhani (Persian: مریم میرزاخانی‎, pronounced [mæɾˈjæm miːɾzɑːxɑːˈniː]; 12 May 1977 – 14 July 2017) was an Iranian mathematician and a professor of mathematics at Stanford University. Her research topics included Teichmüller theory, hyperbolic geometry, ergodic theory, and symplectic geometry. In 2005, as a result of her research, she was honored in Popular Science's fourth annual "Brilliant 10" in which she was acknowledged as one of the top 10 young minds who have pushed their fields in innovative directions.

On 13 August 2014, Mirzakhani was honored with the Fields Medal, the most prestigious award in mathematics. Thus, she became both the first, and to date, the only woman and the first Iranian to be honored with the award. The award committee cited her work in "the dynamics and geometry of Riemann surfaces and their moduli spaces".

On 14 July 2017, Mirzakhani died of breast cancer at the age of 40.

Marie-Sophie Germain (French: [maʁi sɔfi ʒɛʁmɛ̃]; 1 April 1776 – 27 June 1831) was a French mathematician, physicist, and philosopher. Despite initial opposition from her parents and difficulties presented by society, she gained education from books in her father's library, including ones by Leonhard Euler, and from correspondence with famous mathematicians such as Lagrange, Legendre, and Gauss (under the pseudonym of «Monsieur LeBlanc»). One of the pioneers of elasticity theory, she won the grand prize from the Paris Academy of Sciences for her essay on the subject. Her work on Fermat's Last Theorem provided a foundation for mathematicians exploring the subject for hundreds of years after. Because of prejudice against her sex, she was unable to make a career out of mathematics, but she worked independently throughout her life. Before her death, Gauss had recommended that she be awarded an honorary degree, but that never occurred. On 27 June 1831, she died from breast cancer. At the centenary of her life, a street and a girls’ school were named after her. The Academy of Sciences established the Sophie Germain Prize in her honor.

Mary Kenneth Keller, B.V.M. (December 17, 1913 – January 10, 1985) was an American Roman Catholic religious sister, educator and pioneer in computer science. She and Irving C. Tang were the first two people to earn a doctorate in computer science in the United States.

Carolyn Jean Spellmann Shoemaker (June 24, 1929 – August 13, 2021) was an American astronomer and a co-discoverer of Comet Shoemaker–Levy 9. She once held the record for most comets discovered by an individual.

Although Shoemaker earned degrees in history, political science and English literature, she had little interest in science until she met and married geologist Eugene M. ("Gene") Shoemaker in 1950–51. She later said that his explanations of his work thrilled her. Despite her relative inexperience and lack of a science degree, California Institute of Technology (Caltech) had no objection to her joining Gene's team there as a research assistant. She had already shown herself to be unusually patient, and demonstrated exceptional stereoscopic vision, which were particularly valuable qualities for looking for objects in near-Earth space.