Topic: Epilepsy

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Musicogenic Seizure

Medicine Medicine/Neurology Epilepsy

Musicogenic seizure, also known as music-induced seizure, is a rare type of seizure, with an estimated prevalence of 1 in 10,000,000 individuals, that arises from disorganized or abnormal brain electrical activity when a person hears or is exposed to a specific type of sound or musical stimuli. There are challenges when diagnosing a music-induced seizure due to the broad scope of triggers, and time delay between a stimulus and seizure. In addition, the causes of musicogenic seizures are not well-established as solely limited cases and research have been discovered and conducted respectively. Nevertheless, the current understanding of the mechanism behind musicogenic seizure is that music triggers the part of the brain that is responsible for evoking an emotion associated with that music. Dysfunction in this system leads to an abnormal release of dopamine, eventually inducing seizure.

Currently, there are diverse intervention strategies that patients can choose from depending on their situations. They can have surgery to remove the region of the brain that generates a seizure. Behavioral therapy is also available; patients are trained to gain emotional control to reduce the frequency of seizure. Medications like carbamazepine and phenytoin (medication for general seizure) also suggest effectiveness to mitigate music-induced seizures.

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