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πŸ”— Spirograph

πŸ”— Brands πŸ”— Toys

Spirograph is a geometric drawing device that produces mathematical roulette curves of the variety technically known as hypotrochoids and epitrochoids. The well known toy version was developed by British engineer Denys Fisher and first sold in 1965.

The name has been a registered trademark of Hasbro Inc. since 1998 following purchase of the company that had acquired the Denys Fisher company. The Spirograph brand was relaunched worldwide in 2013, with its original product configurations, by Kahootz Toys.

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πŸ”— Great Man-Made River

πŸ”— Africa πŸ”— Water πŸ”— Rivers πŸ”— Africa/Libya

The Great Man-Made River (GMMR, Ψ§Ω„Ω†Ω‡Ψ± Ψ§Ω„Ψ΅Ω†Ψ§ΨΉΩŠ Ψ§Ω„ΨΉΨΈΩŠΩ…) is a network of pipes that supplies fresh water obtained from the Nubian Sandstone Aquifer System fossil aquifer across Libya. It is the world's largest irrigation project. The project utilizes a pipeline system that pumps water from the Nubian Sandstone Aquifer System from down south in Libya to cities in the populous Libyan northern Mediterranean coast including Tripoli and Benghazi. The water covers a distance of up to 1,600 kilometers and provides 70% of all freshwater used in Libya.

According to its website, it is the largest underground network of pipes (2,820 kilometres (1,750Β mi)) and aqueducts in the world. It consists of more than 1,300 wells, most more than 500 m deep, and supplies 6,500,000 m3 of fresh water per day to the cities of Tripoli, Benghazi, Sirte and elsewhere. The late Libyan Leader Muammar Gaddafi described it as the "Eighth Wonder of the World".

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πŸ”— ISO 3103: an international standard for brewing tea

πŸ”— Food and drink πŸ”— Food and drink/Beverages

ISO 3103 is a standard published by the International Organization for Standardization (commonly referred to as ISO), specifying a standardized method for brewing tea, possibly sampled by the standardized methods described in ISO 1839. It was originally laid down in 1980 as BS 6008:1980 by the British Standards Institution, and a revision was published in December, 2019 as ISO/NP 3103. It was produced by ISO Technical Committee 34 (Food products), Sub-Committee 8 (Tea).

The abstract states the following:

The method consists in extracting of soluble substances in dried tea leaf, contained in a porcelain or earthenware pot, by means of freshly boiling water, pouring of the liquor into a white porcelain or earthenware bowl, examination of the organoleptic properties of the infused leaf, and of the liquor with or without milk, or both.

This standard is not meant to define the proper method for brewing tea intended for general consumption, but rather to document a tea brewing procedure where meaningful sensory comparisons can be made. An example of such a test would be a taste-test to establish which blend of teas to choose for a particular brand or basic label in order to maintain a consistent tasting brewed drink from harvest to harvest.

The work was the winner of the parodic Ig Nobel Prize for Literature in 1999.

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πŸ”— Delphi Method

πŸ”— Statistics πŸ”— Futures studies

The Delphi method or Delphi technique ( DEL-fy; also known as Estimate-Talk-Estimate or ETE) is a structured communication technique or method, originally developed as a systematic, interactive forecasting method which relies on a panel of experts. The technique can also be adapted for use in face-to-face meetings, and is then called mini-Delphi or Estimate-Talk-Estimate (ETE). Delphi has been widely used for business forecasting and has certain advantages over another structured forecasting approach, prediction markets.

Delphi is based on the principle that forecasts (or decisions) from a structured group of individuals are more accurate than those from unstructured groups. The experts answer questionnaires in two or more rounds. After each round, a facilitator or change agent provides an anonymised summary of the experts' forecasts from the previous round as well as the reasons they provided for their judgments. Thus, experts are encouraged to revise their earlier answers in light of the replies of other members of their panel. It is believed that during this process the range of the answers will decrease and the group will converge towards the "correct" answer. Finally, the process is stopped after a predefined stop criterion (e.g., number of rounds, achievement of consensus, stability of results), and the mean or median scores of the final rounds determine the results.

Special attention has to be paid to the formulation of the Delphi theses and the definition and selection of the experts in order to avoid methodological weaknesses that severely threaten the validity and reliability of the results.

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πŸ”— Burned house horizon

πŸ”— History πŸ”— Europe πŸ”— Ukraine πŸ”— Archaeology πŸ”— Romania πŸ”— Moldova

In the archaeology of Neolithic Europe, the burned house horizon is the geographical extent of the phenomenon of presumably intentionally burned settlements.

This was a widespread and long-lasting tradition in what is now Southeastern and Eastern Europe, lasting from as early as 6500 BCE (the beginning of the Neolithic) to as late as 2000 BCE (the end of the Chalcolithic and the beginning of the Bronze Age). A notable representative of this tradition is the Cucuteni-Trypillian culture, which was centered on the burned-house horizon both geographically and temporally.

There is still a discussion in the study of Neolithic and Eneolithic Europe whether the majority of burned houses were intentionally set alight or not.

Although there is still debate about the why house burning was practiced, the evidence seems to indicate that it was highly unlikely to have been accidental. There is also debate about why this would have been done deliberately and regularly, since these burnings could destroy the entire settlement. However, in recent years, the consensus has begun to gel around the "domicide" theory supported by Tringham, Stevanovic and others.

Cucuteni-Trypillian settlements were completely burned every 75–80 years, leaving behind successive layers consisting mostly of large amounts of rubble from the collapsed wattle-and-daub walls. This rubble was mostly ceramic material that had been created as the raw clay used in the daub of the walls became vitrified from the intense heat that would have turned it a bright orange color during the conflagration that destroyed the buildings, much the same way that raw clay objects are turned into ceramic products during the firing process in a kiln. Moreover, the sheer amount of fired-clay rubble found within every house of a settlement indicates that a fire of enormous intensity would have raged through the entire community to have created the volume of material found.

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πŸ”— Kalman Filter

πŸ”— Mathematics πŸ”— Statistics πŸ”— Systems πŸ”— Robotics πŸ”— Systems/Control theory

In statistics and control theory, Kalman filtering, also known as linear quadratic estimation (LQE), is an algorithm that uses a series of measurements observed over time, containing statistical noise and other inaccuracies, and produces estimates of unknown variables that tend to be more accurate than those based on a single measurement alone, by estimating a joint probability distribution over the variables for each timeframe. The filter is named after Rudolf E. KΓ‘lmΓ‘n, one of the primary developers of its theory.

The Kalman filter has numerous applications in technology. A common application is for guidance, navigation, and control of vehicles, particularly aircraft, spacecraft and dynamically positioned ships. Furthermore, the Kalman filter is a widely applied concept in time series analysis used in fields such as signal processing and econometrics. Kalman filters also are one of the main topics in the field of robotic motion planning and control and can be used in trajectory optimization. The Kalman filter also works for modeling the central nervous system's control of movement. Due to the time delay between issuing motor commands and receiving sensory feedback, use of the Kalman filter supports a realistic model for making estimates of the current state of the motor system and issuing updated commands.

The algorithm works in a two-step process. In the prediction step, the Kalman filter produces estimates of the current state variables, along with their uncertainties. Once the outcome of the next measurement (necessarily corrupted with some amount of error, including random noise) is observed, these estimates are updated using a weighted average, with more weight being given to estimates with higher certainty. The algorithm is recursive. It can run in real time, using only the present input measurements and the previously calculated state and its uncertainty matrix; no additional past information is required.

Optimality of the Kalman filter assumes that the errors are Gaussian. In the words of Rudolf E. KΓ‘lmΓ‘n: "In summary, the following assumptions are made about random processes: Physical random phenomena may be thought of as due to primary random sources exciting dynamic systems. The primary sources are assumed to be independent gaussian random processes with zero mean; the dynamic systems will be linear." Though regardless of Gaussianity, if the process and measurement covariances are known, the Kalman filter is the best possible linear estimator in the minimum mean-square-error sense.

Extensions and generalizations to the method have also been developed, such as the extended Kalman filter and the unscented Kalman filter which work on nonlinear systems. The underlying model is a hidden Markov model where the state space of the latent variables is continuous and all latent and observed variables have Gaussian distributions. Also, Kalman filter has been successfully used in multi-sensor fusion, and distributed sensor networks to develop distributed or consensus Kalman filter.

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πŸ”— Spaghettification

πŸ”— Physics πŸ”— Physics/relativity

In astrophysics, spaghettification (sometimes referred to as the noodle effect) is the vertical stretching and horizontal compression of objects into long thin shapes (rather like spaghetti) in a very strong non-homogeneous gravitational field; it is caused by extreme tidal forces. In the most extreme cases, near black holes, the stretching is so powerful that no object can withstand it, no matter how strong its components. Within a small region the horizontal compression balances the vertical stretching so that small objects being spaghettified experience no net change in volume.

Stephen Hawking described the flight of a fictional astronaut who, passing within a black hole's event horizon, is "stretched like spaghetti" by the gravitational gradient (difference in strength) from head to toe. The reason this happens would be that the gravity force exerted by the singularity would be much stronger at one end of the body than the other. If one were to fall into a black hole feet first, the gravity at their feet would be much stronger than at their head, causing the person to be vertically stretched. Along with that, the right side of the body will be pulled to the left, and the left side of the body will be pulled to the right, horizontally compressing the person. However, the term "spaghettification" was established well before this. Spaghettification of a star was imaged for the first time in 2018 by researchers observing a pair of colliding galaxies approximately 150 million light-years from Earth.

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πŸ”— Battle of Los Angeles

πŸ”— California πŸ”— Military history πŸ”— Military history/North American military history πŸ”— Military history/United States military history πŸ”— Military history/World War II πŸ”— Paranormal πŸ”— California/Southern California

The Battle of Los Angeles, also known as the Great Los Angeles Air Raid, is the name given by contemporary sources to a rumored attack on the mainland United States by Imperial Japan and the subsequent anti-aircraft artillery barrage which took place from late 24 February to early 25 February 1942, over Los Angeles, California. The incident occurred less than three months after the U.S. entered World War II in response to the Imperial Japanese Navy's surprise attack on Pearl Harbor, and one day after the bombardment of Ellwood near Santa Barbara on 23 February. Initially, the target of the aerial barrage was thought to be an attacking force from Japan, but speaking at a press conference shortly afterward, Secretary of the Navy Frank Knox called the purported attack a "false alarm". Newspapers of the time published a number of reports and speculations of a cover-up.

When documenting the incident in 1949, the United States Coast Artillery Association identified a meteorological balloon sent aloft at 1:00Β am as having "started all the shooting" and concluded that "once the firing started, imagination created all kinds of targets in the sky and everyone joined in". In 1983, the U.S. Office of Air Force History attributed the event to a case of "war nerves" triggered by a lost weather balloon and exacerbated by stray flares and shell bursts from adjoining batteries.

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πŸ”— Potential Collapse of the West Antarctic Ice Sheet

πŸ”— Climate change πŸ”— Environment πŸ”— Antarctica πŸ”— Glaciers

The Western Antarctic Ice Sheet (WAIS) is the segment of the continental ice sheet that covers West Antarctica, the portion of Antarctica on the side of the Transantarctic Mountains that lies in the Western Hemisphere. The WAIS is classified as a marine-based ice sheet, meaning that its bed lies well below sea level and its edges flow into floating ice shelves. The WAIS is bounded by the Ross Ice Shelf, the Ronne Ice Shelf, and outlet glaciers that drain into the Amundsen Sea.

πŸ”— HeLa, the oldest and most commonly used human cell line

πŸ”— Viruses πŸ”— Biology πŸ”— Philosophy πŸ”— Philosophy/Contemporary philosophy πŸ”— History of Science πŸ”— Molecular and Cell Biology πŸ”— Philosophy/Ethics πŸ”— Genetics πŸ”— Evolutionary biology πŸ”— Science Policy πŸ”— Molecular Biology/Molecular and Cell Biology

HeLa (; also Hela or hela) is an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line. The line was derived from cervical cancer cells taken on February 8, 1951 from Henrietta Lacks, a patient who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which gives rise to its extensive use in scientific research.

The cells from Lacks's cancerous cervical tumor were taken without her knowledge or consent, which was common practice at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would only survive for a few days. Scientists would spend more time trying to keep the cells alive than performing actual research on them. Cells from Lacks' tumor behaved differently. As was custom for Gey's lab assistant, she labeled the culture 'HeLa', the first two letters of the patient's first and last name; this became the name of the cell line.

These were the first human cells grown in a lab that were naturally "immortal", meaning that they do not die after a set number of cell divisions (i.e. cellular senescence). These cells could be used for conducting a multitude of medical experimentsβ€”if the cells died, they could simply be discarded and the experiment attempted again on fresh cells from the culture. This represented an enormous boon to medical and biological research, as previously stocks of living cells were limited and took significant effort to culture.

The stable growth of HeLa enabled a researcher at the University of Minnesota hospital to successfully grow polio virus, enabling the development of a vaccine, and by 1952, Jonas Salk developed a vaccine for polio using these cells. To test Salk's new vaccine, the cells were put into mass production in the first-ever cell production factory.

In 1953, HeLa cells were the first human cells successfully cloned and demand for the HeLa cells quickly grew in the nascent biomedical industry. Since the cells' first mass replications, they have been used by scientists in various types of investigations including disease research, gene mapping, effects of toxic substances on organisms, and radiation on humans. Additionally, HeLa cells have been used to test human sensitivity to tape, glue, cosmetics, and many other products.

Scientists have grown an estimated 50 million metricΒ tons of HeLa cells, and there are almost 11,000Β patents involving these cells.

The HeLa cell lines are also notorious for invading other cell cultures in laboratory settings. Some have estimated that HeLa cells have contaminated 10–20% of all cell lines currently in use.

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