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🔗 Medicine 🔗 Dogs 🔗 Psychology 🔗 Anthropology 🔗 India 🔗 Medicine/Psychiatry

Puppy pregnancy syndrome (PPS) is a psychosomatic illness in humans brought on by mass hysteria.

The syndrome is thought to be localized in villages in several states of India, including West Bengal, Assam, Bihar, Jharkhand, Orissa, and Chhattisgarh, and has been reported by tens of thousands of individuals. It is far more prevalent in areas with little access to education.

People suffering from PPS believe that shortly after being bitten by a dog, puppies are conceived within their abdomen. This is said to be especially likely if the dog is sexually excited at the time of the attack. Victims are said to bark like dogs and have reported being able to see the puppies inside them when looking at water or hear them growling in their abdomen. It is believed that the victims will eventually die – especially men, who will give birth to their puppies through the penis.

Witch doctors offer oral cures, which they claim will dissolve the puppies, allowing them to pass through the digestive system and be excreted "without the knowledge of the patient".

Doctors in India have tried to educate the public about the dangers of believing in this condition. Most sufferers are referred to psychiatric services, but in some instances patients fail to take anti-rabies medication before symptom onset, thinking that they are pregnant with a puppy and that folk medicine will cure them. This misbelief is further compounded by witch doctors who state that their medicine will fail if sufferers seek standard treatment.

Some psychiatrists believe that PPS meets the criteria for a culture-bound disorder.

🔗 Medicine 🔗 Cats 🔗 Microbiology 🔗 Veterinary medicine

Toxoplasma gondii () is a parasitic protozoan (specifically an apicomplexan) that causes toxoplasmosis. Found worldwide, T. gondii is capable of infecting virtually all warm-blooded animals,^: 1 but felids are the only known definitive hosts in which the parasite may undergo sexual reproduction.

In rodents, T. gondii alters behavior in ways that increase the rodents' chances of being preyed upon by felids. Support for this "manipulation hypothesis" stems from studies showing that T. gondii-infected rats have a decreased aversion to cat urine while infection in mice lowers general anxiety, increases explorative behaviors and increases a loss of aversion to predators in general. Because cats are one of the only hosts within which T. gondii can sexually reproduce, such behavioral manipulations are thought to be evolutionary adaptations that increase the parasite's reproductive success since rodents that do not avoid cat habitations will more likely become cat prey. The primary mechanisms of T. gondii–induced behavioral changes in rodents occur through epigenetic remodeling in neurons that govern the relevant behaviors (e.g. hypomethylation of arginine vasopressin-related genes in the medial amygdala, which greatly decrease predator aversion).

In humans, particularly infants and those with weakened immunity, T. gondii infection is generally asymptomatic but may lead to a serious case of toxoplasmosis. T. gondii can initially cause mild, flu-like symptoms in the first few weeks following exposure, but otherwise, healthy human adults are asymptomatic. This asymptomatic state of infection is referred to as a latent infection, and it has been associated with numerous subtle behavioral, psychiatric, and personality alterations in humans. Behavioral changes observed between infected and non-infected humans include a decreased aversion to cat urine (but with divergent trajectories by gender) and an increased risk of schizophrenia. Preliminary evidence has suggested that T. gondii infection may induce some of the same alterations in the human brain as those observed in rodents. Many of these associations have been strongly debated and newer studies have found them to be weak, concluding:

On the whole, there was little evidence that T. gondii was related to increased risk of psychiatric disorder, poor impulse control, personality aberrations, or neurocognitive impairment.

T. gondii is one of the most common parasites in developed countries; serological studies estimate that up to 50% of the global population has been exposed to, and may be chronically infected with, T. gondii; although infection rates differ significantly from country to country. Estimates have shown the highest IgG seroprevalence to be in Ethiopia, at 64.2%, as of 2018.

🔗 Biography 🔗 Medicine 🔗 Biography/science and academia 🔗 History of Science 🔗 Hungary 🔗 Medicine/Society and Medicine

Ignaz Philipp Semmelweis (German: [ˈɪɡnaːts ˈzɛml̩vaɪs]; Hungarian: Semmelweis Ignác Fülöp [ˈsɛmmɛlvɛjs ˈiɡnaːts ˈfyløp]; 1 July 1818 – 13 August 1865) was a Hungarian physician and scientist of German descent who was an early pioneer of antiseptic procedures and was described as the "saviour of mothers". Postpartum infection, also known as puerperal fever or childbed fever, consists of any bacterial infection of the reproductive tract following birth and in the 19th century was common and often fatal. Semmelweis discovered that the incidence of infection could be drastically reduced by requiring healthcare workers in obstetrical clinics to disinfect their hands. In 1847, he proposed hand washing with chlorinated lime solutions at Vienna General Hospital's First Obstetrical Clinic, where doctors' wards had thrice the mortality of midwives' wards. The maternal mortality rate dropped from 18% to less than 2%, and he published a book of his findings, Etiology, Concept and Prophylaxis of Childbed Fever, in 1861.

Despite his research, Semmelweis's observations conflicted with the established scientific and medical opinions of the time and his ideas were rejected by the medical community. He could offer no theoretical explanation for his findings of reduced mortality due to hand-washing, and some doctors were offended at the suggestion that they should wash their hands and mocked him for it. In 1865, the increasingly outspoken Semmelweis allegedly suffered a nervous breakdown and was committed to an asylum by his colleagues. In the asylum, he was beaten by the guards. He died 14 days later from a gangrenous wound on his right hand that may have been caused by the beating.

His findings earned widespread acceptance only years after his death, when Louis Pasteur confirmed the germ theory, giving Semmelweis' observations a theoretical explanation, and Joseph Lister, acting on Pasteur's research, practised and operated using hygienic methods with great success.

🔗 United States 🔗 Biography 🔗 Medicine 🔗 Biology 🔗 Biography/science and academia 🔗 India 🔗 Molecular and Cell Biology 🔗 Medicine/Medical genetics 🔗 United States/Asian Americans

Har Gobind Khorana (9 January 1922 – 9 November 2011) was an Indian-American biochemist. While on the faculty of the University of Wisconsin–Madison, he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and Robert W. Holley for research that showed the order of nucleotides in nucleic acids, which carry the genetic code of the cell and control the cell's synthesis of proteins. Khorana and Nirenberg were also awarded the Louisa Gross Horwitz Prize from Columbia University in the same year.

Born in British India, Khorana served on the faculties of three universities in North America. He became a naturalized citizen of the United States in 1966, and received the National Medal of Science in 1987.

🔗 Medicine 🔗 Athletics 🔗 Food and drink 🔗 Medicine/Toxicology 🔗 Sports 🔗 Horse racing

The poppy seed defence is a commonly cited reason to avoid any sanction for failing a drug test. The defence asserts that a suspect's positive result was a result of the person having consumed poppy seeds prior to taking the test. It has been recognised in medical and legal fields as a valid defence.

🔗 International relations 🔗 Disaster management 🔗 Medicine 🔗 Death

A pandemic (from Greek πᾶν pan "all" and δῆμος demos "people") is a disease epidemic that has spread across a large region, for instance multiple continents, or worldwide. A widespread endemic disease with a stable number of infected people is not a pandemic. Further, flu pandemics generally exclude recurrences of seasonal flu.

Throughout history, there have been a number of pandemics of diseases such as smallpox and tuberculosis. One of the most devastating pandemics was the Black Death (also known as The Plague), which killed an estimated 75–200 million people in the 14th century. Other notable pandemics include the 1918 influenza pandemic (Spanish flu) and the 2009 flu pandemic (H1N1). Current pandemics include HIV/AIDS and the 2019 coronavirus disease, which was declared a pandemic on 11 March 2020 by the World Health Organization (WHO).