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🔗 Human rights 🔗 Military history 🔗 Military history/North American military history 🔗 Military history/United States military history 🔗 Military history/Military science, technology, and theory 🔗 Military history/Weaponry 🔗 Medicine 🔗 Biology 🔗 Military history/World War II 🔗 Military history/Cold War 🔗 United States History 🔗 Medicine/Society and Medicine

Unethical human experimentation in the United States describes numerous experiments performed on human test subjects in the United States that have been considered unethical, and were often performed illegally, without the knowledge, consent, or informed consent of the test subjects. Such tests have occurred throughout American history, but particularly in the 20th century. The experiments include: the exposure of humans to many chemical and biological weapons (including infection with deadly or debilitating diseases), human radiation experiments, injection of toxic and radioactive chemicals, surgical experiments, interrogation and torture experiments, tests involving mind-altering substances, and a wide variety of others. Many of these tests were performed on children, the sick, and mentally disabled individuals, often under the guise of "medical treatment". In many of the studies, a large portion of the subjects were poor, racial minorities, or prisoners.

Funding for many of the experiments was provided by the United States government, especially the United States military, the Central Intelligence Agency, or private corporations involved with military activities. The human research programs were usually highly secretive, and in many cases information about them was not released until many years after the studies had been performed.

The ethical, professional, and legal implications of this in the United States medical and scientific community were quite significant, and led to many institutions and policies that attempted to ensure that future human subject research in the United States would be ethical and legal. Public outrage in the late 20th century over the discovery of government experiments on human subjects led to numerous congressional investigations and hearings, including the Church Committee and Rockefeller Commission, both of 1975, and the 1994 Advisory Committee on Human Radiation Experiments, among others.

🔗 Internet 🔗 China

50 Cent Party, 50 Cent Army and wumao ( WOO-mow) are terms for Internet commentators who are hired by the authorities of the People's Republic of China to manipulate public opinion and disseminate disinformation to the benefit of the governing Chinese Communist Party (CCP). It was created during the early phases of the Internet's rollout to the wider public in China.

The name is derived from the allegation that such commentators are paid RMB¥0.50 for every post. These commentators create comments or articles on popular Chinese social media networks that are intended to derail discussions which are critical of the CCP, promoting narratives that serve the government's interests and insulting or spreading misinformation about political opponents of the Chinese government, both domestic and abroad. Some of these commentators have labeled themselves ziganwu (Chinese: 自干五, short for 自带干粮的五毛, lit. 'wumao who bring their own dry rations'), claiming they are not paid by authorities and express their support for the Chinese government out of their own volition.

Authors of a paper published in 2017 in the American Political Science Review estimate that the Chinese government fabricates 488 million social media posts per year. In contrast to common assumptions, the 50 Cent Party consists mostly of paid bureaucrats who respond to government directives and rarely defend their government from criticism or engage in direct arguments because "... the goal of this massive secretive operation is instead to distract the public and change the subject." Around 80% of the analysed posts involve pro-China cheerleading with inspirational slogans, and 13% involve general praise and suggestions on governmental policies. Despite the common allegation of the commentators getting paid for their posts, the paper suggested there was "no evidence" that they are paid anything for their posts, instead being required to do so as a part of their official party duties.

Research by professors at Harvard, Stanford, and UC San Diego indicated a "massive secretive operation" to fill China's Internet with propaganda, and has resulted in some 488 million posts written by fake social media accounts, representing about 0.6% of the 80 billion posts generated on Chinese social media. To maximize their influence, such pro-government comments are made largely during times of intense online debate, and when online protests have a possibility of transforming into real life actions. The colloquial term wumao has also been used by some English speakers outside of China as an insult against people with perceived pro-CCP bias.

🔗 Medicine 🔗 Medicine/Neurology 🔗 Epilepsy

Musicogenic seizure, also known as music-induced seizure, is a rare type of seizure, with an estimated prevalence of 1 in 10,000,000 individuals, that arises from disorganized or abnormal brain electrical activity when a person hears or is exposed to a specific type of sound or musical stimuli. There are challenges when diagnosing a music-induced seizure due to the broad scope of triggers, and time delay between a stimulus and seizure. In addition, the causes of musicogenic seizures are not well-established as solely limited cases and research have been discovered and conducted respectively. Nevertheless, the current understanding of the mechanism behind musicogenic seizure is that music triggers the part of the brain that is responsible for evoking an emotion associated with that music. Dysfunction in this system leads to an abnormal release of dopamine, eventually inducing seizure.

Currently, there are diverse intervention strategies that patients can choose from depending on their situations. They can have surgery to remove the region of the brain that generates a seizure. Behavioral therapy is also available; patients are trained to gain emotional control to reduce the frequency of seizure. Medications like carbamazepine and phenytoin (medication for general seizure) also suggest effectiveness to mitigate music-induced seizures.

🔗 Meteorology 🔗 Tropical cyclones

A hypercane is a hypothetical class of extreme tropical cyclone that could form if ocean temperatures reached approximately 50 °C (122 °F), which is 15 °C (27 °F) warmer than the warmest ocean temperature ever recorded. Such an increase could be caused by a large asteroid or comet impact, a large supervolcanic eruption, a large submarine flood basalt, or extensive global warming. There is some speculation that a series of hypercanes resulting from an impact by a large asteroid or comet contributed to the demise of the non-avian dinosaurs. The hypothesis was created by Kerry Emanuel of MIT, who also coined the term.

🔗 Medicine 🔗 Health and fitness

The protein leverage hypothesis states that human beings will prioritize the consumption of protein in food over other dietary components, and will eat until protein needs have been met, regardless of energy content, thus leading to over-consumption of foodstuffs when their protein content is low.

This hypothesis has been put forward as a potential explanation of the obesity epidemic. Empirical tests have provided some evidence to confirm the hypothesis with one study suggesting that this could be a link between ultra-processed foods and the prevalence of obesity in the developed world.

In the 1980s, David Raubenheimer and Stephen Simpson, researchers now at the University of Sydney, began to study appetite and food intake in locusts. By studying responses to artificial diets with differing compositions of protein and carbohydrate, they developed the protein leverage hypothesis. Their experiments showed that those who aren't getting enough protein in their diet will continue to be hungry, even when their overall caloric intake is high. "Protein decoys", such as ultraprocessed savory foods that contain little protein (e.g., barbecue chips), are likely to be attractive and to result in overeating. The hormone FGF21, which is released from the liver, can drive savory-seeking behavior under conditions of low protein intake. However, extremely high protein diets can also have drawbacks. In 2020 Simpson and Raubenheimer published the popular science book Eat Like the Animals: What Nature Teaches Us about the Science of Healthy Eating, which details their experiments. For lifelong health they recommend eating a balanced diet with more fiber and fewer fats and carbohydrates rather than an extremely high protein diet.

In 1995, Australian researcher Susanna Holt developed the concept of satiety value, a measure of how much a given food is likely to satisfy the hunger of someone. High protein foods have been found to have high satiety values, though these are outmatched by potatoes and oats (which have a low glycemic index). Fruits rank similarly to high protein foods (likely due to their high level of dietary fibre).

🔗 United States 🔗 Companies 🔗 Video games 🔗 United States/Washington - Seattle 🔗 United States/Washington

Valve Corporation, also known as Valve Software, is an American video game developer, publisher, and digital distribution company headquartered in Bellevue, Washington. It is the developer of the software distribution platform Steam and the Half-Life, Counter-Strike, Portal, Day of Defeat, Team Fortress, Left 4 Dead, and Dota series.

Valve was founded in 1996 by former Microsoft employees Gabe Newell and Mike Harrington. Their debut product, the PC first-person shooter Half-Life, was released in 1998 to critical acclaim and commercial success, after which Harrington left the company. In 2003, Valve launched Steam, which accounted for around half of digital PC game sales by 2011. By 2012, Valve employed around 250 people and was reportedly worth over US$3 billion, making it the most profitable company per employee in the United States. In the 2010s, Valve began developing hardware, such as the Steam Machine, a brand of gaming PCs, as well as the HTC Vive and Valve Index virtual reality headsets.

🔗 Biography 🔗 Biography/science and academia 🔗 University of Pennsylvania

George Harry Heilmeier (May 22, 1936 – April 21, 2014) was an American engineer, manager, and a pioneering contributor to liquid crystal displays (LCDs), for which he was inducted into the National Inventors Hall of Fame. Heilmeier's work is an IEEE Milestone.

🔗 Biography 🔗 Literature 🔗 Women writers 🔗 Biography/arts and entertainment

Barbara Newhall Follett (March 4, 1914 – disappeared December 7, 1939) was an American child prodigy novelist. Her first novel, The House Without Windows, was published in January 1927, when she was twelve years old. Her next novel, The Voyage of the Norman D.w, received critical acclaim when she was fourteen.

In December 1939, aged 25, Follett reportedly became depressed with her marriage and walked out of her apartment, never to be seen again.

🔗 Finance & Investment 🔗 COVID-19 🔗 Economics

The 2020 stock market crash is a global stock market crash that began on 20 February, 2020. On 12 February, the Dow Jones Industrial Average, the NASDAQ Composite, and S&P 500 Index all finished at record highs (while the NASDAQ and S&P 500 reached subsequent record highs on 19 February). From 24 to 28 February, stock markets worldwide reported their largest one-week declines since the 2008 financial crisis, thus entering a correction. Global markets into early March became extremely volatile, with large swings occurring in global markets. On 9 March, most global markets reported severe contractions, mainly in response to the 2019–20 coronavirus pandemic and an oil price war between Russia and the OPEC countries led by Saudi Arabia. This became colloquially known as Black Monday I, and at the time was the worst drop since the Great Recession in 2008.

Three days after Black Monday I there was another drop, Black Thursday, where stocks across Europe and North America fell more than 9%. Wall Street experienced its largest single-day percentage drop since Black Monday in 1987, and the FTSE MIB of the Borsa Italiana fell nearly 17%, becoming the worst-hit market during Black Thursday. Despite a temporary rally on 13 March (with markets posting their best day since 2008), all three Wall Street indexes fell more than 12% when markets re-opened on 16 March. At least one benchmark stock market index in all G7 countries and 14 of the G20 countries have been declared to be in bear markets.

As of March 2020, global stocks have seen a downturn of at least 25% during the crash, and 30% in most G20 nations. Goldman Sachs has warned that the US GDP will shrink 29% by the end of the 2nd quarter of 2020, and that unemployment may skyrocket to at least 9%. Australian Prime Minister Scott Morrison has called the looming economic crisis 'akin to the Great Depression'.

🔗 Microbiology

Cable bacteria are filamentous bacteria that conduct electricity across distances over 1 cm in sediment and groundwater aquifers. Cable bacteria allow for long distance electron transport, which connects electron donors to electron acceptors, connecting previously separated oxidation and reduction reactions. Cable bacteria couple the reduction of oxygen or nitrate at the sediment's surface to the oxidation of sulfide in the deeper, anoxic, sediment layers.