An epidemic begins to spread throughout the globe, causing humankind to lose their sensory perceptions one by one. The story focuses on two people: Susan, one of a team of epidemiologists who are trying to find the causes of the disease, and Michael, a chef who works at a busy restaurant located next to Susan's flat. The two meet and get to know each other as the epidemic progresses, a relationship which soon turns to love. Humans begin to lose their senses one at a time. Each loss is preceded by an outburst of an intense feeling or urge. First, people begin suffering uncontrollable bouts of crying and this is soon followed by the loss of their sense of smell. An outbreak of irrational panic and anxiety, closely followed by a bout of frenzied gluttony, precedes the loss of the sense of taste. The film depicts people trying to adapt to each loss and trying to carry on living as best they can, rediscovering their remaining senses as they do so. Michael and his co-workers do their best to cook food for people who cannot smell nor taste. The loss of hearing comes next and is accompanied by an outbreak of extreme anger and rage. Michael experiences it first and is verbally abusive at Susan who flees in fear, losing her own hearing shortly afterwards. Despite her knowledge that it was the disease that caused the outburst, Susan cannot face Michael again. People struggle to adjust and to go on living. One day, every person on Earth suddenly experiences a feeling of joyful euphoria. Susan realizes she both forgives and still loves Michael and rushes to his job. The two find each other and embrace just as they, and the rest of the world, become blind.

By 2022, the cumulative effects of overpopulation, global warming, and pollution have caused ecocide, leading to severe worldwide shortages of food, water, and housing, bringing human civilization to the brink of collapse. New York City has a population of 40 million, and only the elite can afford spacious apartments, clean water, and natural food in walled-off communities patrolled by armed guards. Their homes are fortified, with moats, security systems, and bodyguards for their tenants. Usually they have sex slaves, who are referred to as "furniture", have no human rights, and are passed from one apartment owner to the next. Meanwhile, the majority live in squalor, haul water from communal spigots, and eat highly processed food wafers made by the Soylent Corporation — a large food processing firm. Their mainstay products, Soylent Red and Soylent Yellow, are a staple food, and the latest product, a new, more nutritious, and flavorful wafer derived from plankton, Soylent Green, is introduced to the populace. NYPD Detective Robert Thorn lives in a cramped apartment with his aged co-worker and friend Sol Roth, a brilliant former college professor and police researcher (referred to as a "Book"), who helps him with his cases. Thorn is called to investigate the murder of the wealthy and influential William R. Simonson, a member of the Soylent Corporation's board, which he suspects was an assassination. With the help of Simonson's concubine Shirl, his investigation leads to a priest whom Simonson had visited shortly before his death. Due to the sanctity of the confessional, the visibly exhausted priest can only hint to Thorn at the contents of the confession. Soon after, the priest is murdered in the confessional by Tab Fielding, Simonson's former bodyguard. Under the direction of Governor Henry C. Santini, Thorn's superiors order him to end the investigation. Still, he continues. He soon becomes aware that a stalker is following him. As Thorn tries to control a violent mob during a Soylent Green shortage riot, he is attacked by the assassin who killed Simonson. The killer shoots three times at Thorn but misses, accidentally striking several innocent bystanders in the crowd. Thorn manages to locate the killer and throw him to the ground. The killer shoots Thorn in the leg before being crushed by the hydraulic shovel of a police riot-control vehicle, which continually scoops up shovelfuls of people in the crowd and swivels to dump them for disposal. In researching the case for Thorn, Roth brings two volumes of the Soylent Oceanographic Survey Report, 2015–2019, taken by Thorn from Simonson's apartment, to the team of other "Books" (elderly former professors and retired judges now turned researchers) at the "Supreme Exchange". The "Books" quickly conclude from the oceanographic reports that the oceans are dying and cannot actually produce the plankton from which Soylent Green is allegedly made, thus revealing that the ingredients in Soylent Green are, in fact, human bodies. This information confirms to Roth that Simonson's murder was ordered by his fellow Soylent Corporation board members, who knew Simonson was increasingly troubled by this truth and feared he might disclose it to the public. Shaken by the truth, Roth decides to "return to the home of God" and seeks assisted suicide at a government clinic. Thorn discovers this and rushes to stop him, but he arrives too late. Before dying, Roth whispers his discovery to Thorn, who is horrified. Thorn moves to uncover proof of crimes against humanity and to bring it to the attention of the Supreme Exchange so the case can be brought to the Council of Nations to take action. Thorn secretly boards a waste truck transporting human bodies from the euthanasia center to a waste-disposal plant, where he witnesses human corpses instead being processed and turned into Soylent Green. Thorn is discovered but escapes. As he returns to the Supreme Exchange, he is ambushed by Fielding and his men. Finding refuge in the church where Simonson confessed, Thorn kills his attackers but is seriously wounded in a gunfight. As paramedics tend to Thorn, he urges his commanding officer, Chief Hatcher, to spread the truth. Thorn shouts to the surrounding crowd, "Soylent Green is people!"

In the year 2678, the spaceship Hunter-Gratzner is struck by micrometeoroids that penetrate the hull, killing the captain and sending it off course toward a nearby planet. First Officer Owens and docking pilot Carolyn Fry attempt an emergency landing. As the ship descends uncontrollably, a panicked Fry prepares to jettison the passengers held in cryostasis to save herself, but Owens intervenes. The ship crash-lands, killing Owens and most of the passengers. The survivors include Fry; Imam Abu al-Walid, escorting three young students (Ali, Hassan and Suleiman) to New Mecca; a teenage boy named Jack; prospectors Shazza and Zeke; wealthy merchant Paris; law enforcement officer William J. Johns; and his prisoner, the dangerous and enigmatic criminal Richard B. Riddick, who escapes in the confusion. While searching for him across the sun-scorched and seemingly barren planet, the group discovers an abandoned geological research settlement with a nonfunctional dropship. When Zeke goes missing, the survivors suspect Riddick. However, Fry investigates a nearby underground cave where she is attacked by aggressive creatures and narrowly escapes. Johns recaptures Riddick and offers to release him in exchange for helping them escape the planet. While exploring the settlement, one of the students, Ali, disturbs a cluster of juvenile creatures, which devour him before retreating underground to avoid the sun, revealing a fatal vulnerability to light. Using an orrery, Fry discovers that a total eclipse—occurring every twenty-two years—is imminent. Once darkness falls, the creatures will emerge to hunt, explaining the fate of the previous settlers. As tension builds, both Johns and Riddick try to win Fry to their side: Fry recounts Riddick's cold pragmatism, while Riddick exposes Johns as a morphine-addicted bounty hunter who had refused to use his drugs to ease Owens' agonizing death. The group races back to the Hunter-Gratzner to retrieve power cells for the dropship, but the total eclipse begins, unleashing thousands of flying creatures that kill Shazza. The survivors take shelter inside the Hunter-Gratzner, but the creatures breach it and devour Hassan. Realizing they must reach the dropship, they enlist Riddick—whose surgically enhanced eyes grant him night vision—to guide them through the darkness. Armed with available and improvised light sources, the group sets out. When the group reaches a narrow canyon teeming with creatures, Paris panics, runs, and is killed. Riddick reveals that Jack is actually a girl disguising herself as a boy, and her menstrual blood is attracting the creatures. In private, Johns suggests to Riddick that they wound Jack and leave her behind as a distraction. Riddick pretends to agree, then attacks Johns—injuring him and leaving him to be killed by the creatures. At Riddick's urging, the remaining group sprints through the canyon as the creatures begin cannibalizing one another. After reaching the other side, rain begins to fall, extinguishing their improvised torches. Suleiman is killed in the ensuing attack. Riddick initially moves on alone but ultimately returns to fight off the creatures and save Jack. He hides Fry, Abu al-Walid, and Jack in a cave, then sets out to retrieve the dropship. Suspicious, Fry follows and finds him preparing to take off and abandon them. Fry pleads with Riddick to help her save the others, but he urges her to escape with him instead. Guilt-ridden over her earlier attempt to sacrifice her passengers, she refuses, admitting she would now die to protect the others. Together, they rescue Abu al-Walid and Jack (with small, bioluminescent native lifeforms), but Riddick is cornered and wounded by the creatures. Fry returns to save him, but she is fatally stabbed by one of the creatures and carried off. Riddick returns to the ship but delays takeoff, allowing the creatures to gather around it before using the engines to incinerate as many as possible. Once in space, Jack asks what they should tell the authorities about him; he tells them that Riddick died on the planet.

Barry Kohler, a young amateur Nazi hunter, spies on a meeting of the fugitive Nazi organisation Kameraden in Paraguay. At this meeting, infamous Auschwitz doctor Josef Mengele issues instructions for the assassinations of 94 civil servants in Western Europe and North America, all of them low-ranking and aged around 65, on particular dates over the next two years. Kohler telephones Ezra Lieberman, a famous (as well as penniless and cynical) Nazi hunter living in Vienna, to inform him of his discovery. While still on the phone, Kohler is surprised by the Kameraden and killed. With the help of his sister Esther, British journalist Sidney Beynon and Jewish-American vigilante leader David Bennett, Lieberman begins investigating the deaths of civil servants fitting the profile who die suddenly over the next few months. He is struck by the fact that all of the dead men have sons aged 13 who look exactly alike, with pale skin, dark hair and blue eyes. He discovers that all of the boys were illegally adopted and that some of the adoptions were facilitated by Kameraden member Frieda Maloney, who has since been jailed. Lieberman interviews Maloney, who tells him that the boys were provided by an intermediary in Brazil. She mentions that one of the adoptive fathers she dealt with, American Henry Wheelock, gave her a newborn puppy in exchange for her baby. Seeking an explanation for the boys' identical appearance, Lieberman consults the biologist Dr Bruckner, who explains the principles of cloning. Lieberman deduces that the boys are clones of Adolf Hitler, all created from a single DNA sample by Mengele, who has also been seeking to ensure that their childhoods imitate that of the original Hitler by having them adopted by parents who resemble Hitler's own abusive father Alois (a civil servant in the Austro-Hungarian Empire) and doting mother Klara. This is done in the hopes that their later lives will follow the same course, and that as adults they will establish new Nazi regimes in their respective countries. The murders of the fathers are part of this plan, designed to reflect the death of Alois when Hitler was 13. Based on this revelation, and the age of Maloney's dog, Lieberman realises that Henry Wheelock is due to be murdered in just four days' time. Alarmed by the progress of Lieberman's investigation and Mengele's increasingly erratic behaviour (after he beats one of his men nearly to death for killing his target on the wrong date), the Kameraden leadership attempts to shut down the project, but Mengele escapes. Lieberman travels to rural Pennsylvania to warn Henry Wheelock, only to discover that Wheelock has already been murdered by Mengele, posing as Lieberman. The doctor badly wounds Lieberman with a gunshot, but is then cornered by the family's vicious Doberman Pinschers (Mengele fears dogs). When Wheelock's son Bobby arrives home from school, Mengele attempts to tell him about his real origins. He makes no attempt to deny killing Wheelock, telling Bobby that he must rise above his worthless adoptive family and embrace his destiny. This enrages the boy, who orders the dogs to kill Mengele. Lieberman recovers a list from Mengele's pocket detailing the identities of all 94 clones, and then collapses from blood loss. As Lieberman recuperates in hospital, he is visited by Bennett who asks him to hand over the list so that his vigilante group can eliminate the clones. Lieberman refuses and instead burns the list, declaring that they are innocent children who may yet grow up to be harmless. The final scene shows Bobby Wheelock gazing in fascination at photographs he took of Mengele's mauled corpse.

Workers building an extension to the London Underground at Hobbs End dig up a skull. Palaeontologist Dr. Matthew Roney identifies it as a five-million-year-old apeman, more ancient than previous finds. Part of a metallic object is uncovered nearby. Believing it to be an unexploded bomb from the London blitz, they call in an army bomb disposal team. Meanwhile, Professor Bernard Quatermass learns that his plans for the colonisation of the Moon are to be taken over by the military, who want to establish missile bases in space. Colonel Breen is assigned to Quatermass's British Experimental Rocket Group. When the bomb disposal team call for Breen's assistance, Quatermass accompanies him to the site. When another skull is found within a chamber of the "bomb", they realise that the object itself must also be five million years old. Noting the ship's imperviousness to heat, Quatermass suspects it is of alien origin. Roney's assistant, Barbara Judd, goes to the site with Quatermass. She becomes intrigued by the name of the area, recalling that "Hob" is an old name for the Devil. A policeman mentions a legend that the bombed-out house opposite the station is haunted. All three go there to investigate. Quatermass and Barbara later find historical accounts of hauntings and other spectral appearances going back centuries, coinciding with disturbances of the ground around Hobbs End. A member of the bomb disposal team witnesses a spectral apparition of Roney's apeman appearing through the object's wall. An attempt to open a sealed chamber in the object using a Borazon drill fails. Later, however, a small hole is seen. The hole widens to reveal the corpses of insectoid creatures with horned heads. An examination of their physiology suggests that they came from Mars. They resemble images of the Devil; Quatermass believes that the spaceship is the source of the spectral images and disturbances. They reveal their findings to the press. Quatermass theorises that the occupants of the spaceship came from a dying Mars. Unable to survive on Earth, they sought to preserve part of their race by creating a colony by proxy, by enhancing the intelligence of and imparting Martian faculties to the indigenous primitive hominids. Quatermass theorises that the insectoids used medical and surgical techniques that were more advanced than those on present-day Earth. These apemen's descendants evolved into humans, retaining the vestiges of Martian influence buried in their subconscious. Breen thinks that the "alien craft" is Nazi propaganda designed to sow fear among Londoners. A government minister believes Breen and decides to unveil the spaceship at a press conference. The drill operator, Sladden, is later overcome by a psychic force and flees. His mind unleashes telekinetic energy displays, disrupting people and property. He comes to rest in a church. Before recuperating, Sladden has a vision of insect creatures under an alien sky. Sladden sees himself as one of them and feels that he has to flee to save his life. At Hobbs End, Quatermass brings a machine which taps into the primeval psyche. While trying to replicate the circumstances under which Sladden was affected, he notices that Barbara has fallen under the spaceship's influence. Using the machine, he records her thoughts. Quatermass presents the recording to the minister and other officials. It shows Martians engaged in what he interprets as a genocidal race purge, to cleanse the Martian hives of all mutations. The minister and Breen dismiss the recording. A power line later is dropped within the craft, giving it a jolt of electrical energy. The effect and range of the spaceship's influence on Londoners increases; they go on a rampage, attacking all those perceived as different, with deadly telekinetic displays of energy. Breen is drawn towards the spaceship and killed by the energy emanating from it. Quatermass falls under the alien control too, but is snapped out of it by Roney, who is unaffected. A small portion of the population turns out to be immune. The psychic energy intensifies, ripping up streets and buildings, while a spectral image of a Martian resembling the image of the Devil of legend towers above London. Recalling stories about how the Devil could be defeated with iron and water, Roney theorises that the Martian energy can be discharged into the earth. Roney climbs a building crane and swings it into the image. The crane bursts into flames as it discharges the energy, killing Roney. The image and its effects on London disappear.

Starman is a love story. It's It Happened One Night — John Carpenter The Voyager 2 space probe, launched in 1977, carries a phonographic disc with a message of peace, inviting alien civilizations to visit Earth. The probe is intercepted by an alien ship traveling through space which then sends a scout vessel to establish first contact with Earth. Instead of greeting the vessel, the U.S. government shoots it down. Crashing in Chequamegon Bay, Wisconsin, the lone alien occupant, looking like a floating ball of energy, finds the home of recently widowed Jenny Hayden. He uses a lock of hair from her deceased husband Scott, to clone a body for himself. The alien "Starman" has seven spheres with him which provide energy to perform miraculous feats. The alien uses the first sphere to send a message to his people stating that Earth is hostile and his spacecraft was destroyed. He arranges to rendezvous with them in three days' time. He then uses the second sphere in self-defense and the third to create a holographic map of the United States, coercing Jenny into taking him to the rendezvous in Arizona. Jenny, however, attempts to escape. Having a very basic understanding of the English language from the phonographic disk, the Starman learns to communicate with Jenny and assures her that he means no harm. He explains that if he does not reach the rendezvous point, Arizona's Barringer Crater, in three days, he will die. Jenny teaches the Starman how to drive a car and use credit cards, so he can continue the journey alone. When he resurrects a dead deer, she is moved and decides to stay with him. The authorities pursue the pair across the country. A police officer shoots and critically wounds Jenny. To escape, the Starman crashes their car into a gas tanker and uses another sphere to protect them from the explosion. They take refuge in a mobile home that is being towed. He uses another sphere to heal Jenny. After being assured that she will recover, he proceeds to hitchhike toward Arizona without her, but Jenny reaches him while he and his driver are stopped at a roadblock. Reunited, they hitchhike together, resuming their journey towards the crater. Later, while stowing away on a railroad boxcar, the two have sex. The Starman tells Jenny, "I gave you a baby tonight." She reveals that she is infertile, but he assures her that she is pregnant. He explains that Scott is the posthumous father, as Starman used Scott's DNA to clone himself. As a child also of Starman, their son will possess all the Starman's knowledge and will grow up to be a teacher. Starman offers to stop the pregnancy if she wishes, but Jenny embraces him, accepting the gift. They accidentally travel too far on the train and arrive in Las Vegas. Jenny loses her wallet. The Starman uses one of their last quarters in a slot machine, which he manipulates to win the $500,000 jackpot. They buy a Cadillac to complete their journey to Arizona. National Security Agency director George Fox learns that the Starman's flight trajectory, prior to being shot down, was to the Barringer Crater. So, he arranges to have the Army capture the Starman, dead or alive. SETI scientist Mark Shermin, another government official involved in the case, criticizes Fox's heavy-handed approach and reminds him that the Starman was invited to Earth. Appalled to learn that Fox is planning to vivisect the alien, Shermin then resolves to help the Starman escape rather than let Fox capture him. Jenny and the dying Starman reach the crater as Army helicopters pursue them. Just as they are surrounded, a large spaceship appears and descends into the crater. Light surrounds the couple and the Starman is fully healed. While preparing to leave, he tells Jenny he will never see her again. Jenny asks him to take her with him, but he says she would die on his world. He then gives her his last sphere, saying that their son will know what to do with it. Jenny watches as the ship departs.

A man named Goreng awakens in a cell numbered 48. His cellmate Trimagasi explains that they are in a tower-style holding facility. Once per day, food arrives on "the platform" that lowers from level 0, stopping for two minutes on each level. Prisoners can only eat while the platform is stopped on their level, and are subjected to fatal temperatures if they keep any food. Prisoners are randomly reassigned to a new level each month. Trimagasi reveals that when assigned to level 132, he and his former cellmate cannibalized someone. One day, a woman named Miharu rides down the platform, whom Trimagasi explains regularly descends the pit to search for her child. Goreng explains that he volunteered to spend six months in the facility in exchange for a diploma, while Trimagasi confides that he is serving a year-long sentence for manslaughter. The following month, they are reassigned to level 171. Trimagasi ties up Goreng and explains his plans to feed himself using Goreng's flesh. When he begins cutting into Goreng's leg, Miharu arrives, attacks Trimagasi, and frees Goreng, who kills Trimagasi. Encouraged by Miharu, Goreng eats Trimagasi's flesh and subsequently becomes haunted by hallucinations of Trimagasi. The next month, Goreng wakes on level 33 with a woman named Imoguiri and her dog, Ramesses II. Imoguiri was the administration official who interviewed Goreng before sending him to the pit, having admitted herself after being diagnosed with terminal cancer. Imoguiri only eats every other day, letting Ramesses II eat on the days that she does not, and tries unsuccessfully to convince the pair below them to ration their food. One day, Miharu arrives injured. Goreng and Imoguiri nurse her back to health. That night, Goreng breaks up a fight between Miharu and Imoguiri to then discover that Miharu has killed Ramesses II. After Miharu leaves, Goreng mentions her child to Imoguiri, who says there are no children in the pit and Miharu came alone. The following morning, Goreng wakes to find that they have been reassigned to level 202 and that Imoguiri has hanged herself. He consumes her flesh, plagued with hallucinations of his former cellmates. The next month, Goreng is assigned to level 6. His new cellmate, Baharat, is a religious man who has been attempting to escape the pit for months. Estimating that there are 250 levels, Goreng convinces Baharat to ride the platform down with him and ration the food. They forbid anyone on the first fifty levels to receive any, arguing that they get to eat every day, and fend off those who defy them. Fellow prisoner Sr. Brambang advises them that civility is more effective than violence and convinces them to send a symbolic message to the administration by leaving a single panna cotta untouched. As they descend further, they hand out portions to the prisoners, attacking those who refuse to cooperate. They encounter Miharu being attacked and try to save her, but she is killed and they are both left severely injured. Goreng and Baharat continue to descend, eventually stopping at level 333, where Goreng notices a child whom he deduces is Miharu's daughter. They get off the platform, letting it continue downward, and reluctantly feed the girl the panna cotta. That night, Baharat shakes Goreng awake and tells him, "The girl is the message." Goreng awakens, revealing this encounter to have been a dream, and finds that the real Baharat has bled to death. Goreng and the girl ride the platform to the very bottom level. Goreng once again hallucinates Trimagasi, who encourages him to get off the platform. Goreng insists that he has to ride the platform back up to the top, as he is the bearer of the "message," but Trimagasi replies, "The message requires no bearer." Goreng gets off the platform and the two walk away, watching as the child ascends.

In 1999 Los Angeles, Hannon Fuller owns a multibillion-dollar computer enterprise and is the inventor of a newly completed virtual reality (VR) simulation of 1937 Los Angeles, filled with simulated humans unaware they are computer programs. When Fuller is murdered just as he begins premature testing of the VR system, his friend and protégé, Douglas Hall, who is also the heir to the company, becomes the primary suspect. The evidence against him is so strong that Hall begins to doubt his own innocence. Between interrogations by LAPD Detective Larry McBain, Hall meets Jane Fuller, Hannon's estranged daughter, who intends to shut down the new VR system. Hall then romances her. When a local bartender is murdered after he claims to have witnessed a meeting between Hall and Fuller on the night Fuller was murdered, Hall is arrested. He is released when Jane gives him an alibi. With the assistance of his associate Jason Whitney, Hall attempts to find a message that Fuller left for him inside the simulation. Entering the virtual reality, Hall becomes a bank clerk named John Ferguson. Hall learns that Fuller left the message with a bartender named Jerry Ashton, who read the message and discovered he is an artificial creation. Ashton becomes suspicious of Hall, as once Hall leaps out of Ferguson in the men's restroom of the hotel where Ashton works, Ferguson does not know where he is. When Hall enters the simulation later, He goes to Ashton and asks about the letter. Frightened and angry about the true nature of his world, Ashton tries to kill Hall. Hall barely survives to escape the VR. McBain informs Hall that Jane does not exist, as Fuller never had a daughter. Hall tracks her down only to discover her double, Natasha Molinaro, working as a grocery store clerk, but Molinaro does not recognize Hall. This leads Hall to perform an experiment outside the VR system, something that Fuller's message instructed him to try: drive to a place where he never would have considered going otherwise. He does so, and discovers a point beyond which the world becomes a crude wireframe model. Hall grasps the intended revelation behind Fuller's message: 1999 Los Angeles is itself a simulation. Jane explains the truth to Hall: his world is one of thousands of virtual worlds, but it is the only one in which one of the occupants has developed a virtual world of their own. Jane Fuller lives in the real world outside the 1990s Los Angeles simulation. After Fuller's death, she entered the virtual version to assume the guise of Fuller's daughter, gain control of the company, and shut down the simulated 1937 reality, a plan foiled by Hall being made the company heir. The virtual Hall is modeled after David, Jane's real-world husband, though Jane has since fallen in love with Hall. David committed the murders via Hall's body, being driven to increasingly jealous and psychopathic behavior from prolonged use of VR to live out his dark fantasies. Whitney enters the 1937 simulation as Ashton, who has kidnapped Ferguson and bound him in the trunk of his car. When Whitney is killed in a car crash inside the 1937 simulation, Ashton's consciousness takes control of Whitney's body in the 1990s simulation and takes Hall hostage. Hall tells Ashton that he is not in the real world, and that they are both products of a VR simulation. Hall takes Ashton to the place where he was 'born': a computer lab. David assumes control of Hall again to kill Ashton and then attempts to rape and murder Jane. Jane is rescued by Detective McBain, who shoots and kills David. McBain at this point has realized the nature of his own reality, and jokingly asks Jane if someone will unplug him. She answers "no", so McBain requests that Jane never meddle with the simulation again. David's death as Hall in the 1990s simulation allows Hall's consciousness to take control of David's body in the real world. He wakes in 2024, connected to a VR system. He disconnects the system and finds Jane and her father, upon whom Hannon Fuller was modeled. Jane wants to tell Hall all about the simulation, and just as she begins, the film ends; the screen image collapses to a thin line of light before going dark, like a computer monitor being turned off.

In 2017, aliens known as Scavengers attack Earth and destroy the Moon, triggering global natural disasters. Although humanity wins the war using nuclear weapons, Earth is left uninhabitable. Sixty years later, the remnants of humanity have relocated to a colony on Saturn 's moon Titan, except for Unit 49—technician Jack and his communications officer Victoria—who are scheduled to join them in two weeks. The pair oversee hydro rigs that convert seawater into fusion energy for the Tet, the last remaining human colony ship in orbit. Though Jack and Victoria are romantically involved and have had their memories erased for security reasons, Jack experiences recurring dreams of an unknown woman. He also secretly visits a hidden, verdant valley where he has built a lakeside cabin and collects relics of Earth's past. While investigating a missing drone—autonomous, highly advanced, and heavily armed machines—Jack is nearly captured by Scavengers. Later, he discovers the Scavengers are transmitting a signal into space. A NASA pod crash-lands at the signal's coordinates, carrying five humans in suspended animation, including the woman from Jack's dreams. A drone arrives and destroys four of the pods, but Jack rescues the remaining one and brings the unconscious woman to Unit 49's base. After reviving her, Jack and Victoria learn that the woman, Julia, has been in stasis aboard the Odyssey spaceship since 2017. Julia insists on recovering the ship's flight recorder. She and Jack are captured by Scavengers and brought to the Raven Rock Mountain Complex. Their leader, Malcolm, reveals that the Scavengers are surviving humans. Malcolm needs Jack to reprogram a captured drone to deliver a nuclear bomb, built from Odyssey's reactor, to the Tet. Jack refuses, so Malcolm releases him and Julia, urging him to seek the truth in the radiation zone, which is supposedly deadly and off-limits. Julia helps Jack recall that she is his wife, and fragments of his memories begin to return. When they arrive back at Unit 49, a devastated Victoria informs Sally, the Tet's mission controller, that she and Jack are no longer an "effective team". A drone activates and kills Victoria. Jack and Julia destroy the drone but crash their aircraft inside the radiation zone. There, they encounter another version of Jack—"Jack-52"—who arrives to repair the drone. Jack subdues him, but Julia is seriously injured in the fight. Jack impersonates his clone to infiltrate Unit 52, meets Victoria-52, and steals medical supplies for Julia. They rest at his cabin. At Raven Rock, Malcolm reveals the truth: humanity lost the war, and the Tet is an alien machine intelligence harvesting Earth's resources. After the Moon's destruction, the Tet deployed thousands of clones of astronaut Jack Harper—brainwashed into obedience—to exterminate the remaining humans. Malcolm had assumed that these clones were inhuman until witnessing Jack show interest in a discarded book, hinting at lingering humanity. Jack reprograms the captured drone, but it is destroyed in a surprise attack by other drones, leaving Malcolm badly wounded. Jack and Julia resolve to deliver the bomb; Julia enters a stasis pod. En route, Jack listens to the Odyssey's flight recorder, which reveals the original Jack Harper and Victoria were astronauts sent to explore Titan before being confronted by the Tet. The pair were captured but not before Jack ejected the remaining crew—including Julia—in stasis pods to protect them. Jack gains access to the Tet by claiming he is delivering Julia, as previously instructed. However, the stasis pod contains a dying Malcolm. Jack and Malcolm detonate the bomb, destroying the Tet and themselves. Julia later awakens at the cabin. Three years later, Julia lives there and it is revealed she had a daughter with Jack. A group of Raven Rock survivors arrives, with Jack-52, who has begun regaining fragments of his identity.

On July 2, 1996, an extraterrestrial mothership, entering Earth's orbit outside the Moon, deploys its flying saucers, each 15 mi (24 km) in diameter, over major cities worldwide. U.S. Marine Captain Steven Hiller and his unit, the Black Knights fighter squadron stationed out of MCAS El Toro, are called back from Independence Day leave; his girlfriend, Jasmine Dubrow, decides to flee Los Angeles with her son, Dylan. Retired combat pilot Russell Casse, now an alcoholic single father and crop duster, sees this as vindication of the alien abduction he has been claiming for 10 years. In New York City, technician David Levinson decodes a signal embedded within global satellite transmissions, realizing it is the aliens' countdown for a coordinated attack. Aided by his ex-wife, White House Communications Director Constance Spano, David and his father Julius reach the Oval Office in Washington, D.C. and alert President Thomas Whitmore. Whitmore orders evacuations of Los Angeles, New York City, and the District of Columbia, but it is too late. Each saucer fires a beam, incinerating every targeted city, killing millions. Whitmore, the Levinsons, and a few others barely escape aboard Air Force One while Jasmine, Dylan, and their dog Boomer take shelter in a tunnel's inspection alcove and escape the destruction of Los Angeles. On July 3, Earth's military retaliations against the invaders are thwarted by the alien warships' force fields. Each saucer launches shielded fighters, devastating the human fighter squadrons and military bases, including Steven's. Steven lures one fighter into the Grand Canyon before ejecting from his plane, blinding the fighter using his parachute and causing it to crash in the Mojave Desert. He subdues the downed alien and flags down the convoy of refugees Russel joined with, transporting the alien to Area 51, where Whitmore's plane has landed. U.S. Defense Secretary Albert Nimziki reveals that a government faction has been involved in a UFO conspiracy since 1947, when one of the invaders' fighters crashed near Roswell, New Mexico. Area 51 houses the refurbished ship and three alien corpses from the crash. Chief scientist Dr. Brackish Okun examines the alien captured by Steven, which awakens, telepathically invades Okun's mind, and psychically attacks Whitmore before the alien is killed by Secret Service agents and military personnel. Whitmore learns the invaders' plan from the psychic attack; they intend to annihilate Earth's inhabitants while harvesting its natural resources, as they have done to other civilizations. Whitmore reluctantly authorizes a trial nuclear attack against a saucer above an evacuated Houston, but while Houston is destroyed, the saucer's force field protects it from the blast. All subsequent nuclear attacks are aborted. Jasmine and Dylan, having commandeered a highway maintenance truck and rescued several survivors, including the badly injured First Lady, Marilyn Whitmore, reunite with Steven who takes them to Area 51, where Marilyn succumbs to her injuries after reuniting with her own family. On July 4, inspired by Julius, David devises a plan to write a computer virus on his laptop and, using the refurbished fighter to dock with it, upload the virus into the mothership's operating system to disable the alien's shields, then using a tactical nuclear weapon to destroy the mothership. Steven volunteers as the mission's pilot, and the U.S. military contacts the remaining airborne squadrons through Morse code to organize a united counterattack. Lacking pilots, Whitmore and General William Grey enlist volunteers with flight experience, including Russell, to fly the remaining jets. Steven marries Jasmine, with David and Constance present, during which the divorced pair reconciles before Steven and David leave on the mission. Entering the mothership, they upload the virus. With the shields down, Whitmore's squadron engages a saucer targeting the Area 51 base. They exhaust their ammunition, and as the saucer readies to fire, Russell sacrifices himself by crashing into its primary weapon, destroying the saucer. Grey orders notifications to resistance groups worldwide about the saucers' critical weakness, leading to their destruction. Steven and David launch the nuclear missile and narrowly escape the destruction of the mothership and all the aliens in it. As humanity celebrates its victory against the aliens, Steven and David are rescued after surviving the crash, and are reunited with their families.

On April 3, 2005, the NDR series robot "Andrew" is introduced into the Martin family home to perform housekeeping and maintenance duties and introduces himself by showing a presentation of the Three Laws of Robotics. The eldest daughter Grace despises Andrew, but her younger sister Amanda is sympathetic to him, and Andrew discovers he feels emotions, and is drawn to spend more time with his "Little Miss". He accidentally breaks one of her glass figurines and is able to carve a new one out of wood, which surprises her father Richard. Richard takes Andrew to NorthAm Robotics to inquire if Andrew's creativity was part of his programming. NorthAm's CEO Dennis Mansky claims this is a problem and offers to scrap Andrew, but instead Richard takes Andrew back home and encourages him to continue his creativity and explore other humanities. Andrew becomes a clockmaker and earns a sizable fortune managed by Richard after they find that robots have no rights under current laws. In 2020, Richard encourages Dennis to retrofit Andrew with the ability to present facial expressions to match his emotions. In 2032, Andrew presents Richard with all the money he has made to ask for his freedom. Wounded by this, Richard refuses but grants Andrew his independence on the condition that he may no longer reside at the Martin home. Andrew builds his own home by the beach. In 2048, Richard is on his death bed, and apologizes to Andrew for banishing him all those years ago. Following Richard's death, Andrew goes on a quest to find other NDR robots that are like him, frequently communicating back to Amanda, who has since married and divorced, and has a son Lloyd and granddaughter Portia. In 2068, Andrew discovers Galatea, an NDR robot that has been modified with a female personality and traits. Andrew becomes interested in how Galatea was modified by Rupert Burns, the son of the original NDR designer, and finds he has a number of potential ideas to help make robots appear more human-like. Andrew agrees to fund Rupert's work and to be a test subject and is soon given a human-like appearance. Andrew finally returns to the Martin home and finds that Amanda has grown old while Portia looks much like her grandmother at her age. Portia is initially cautious of Andrew, but soon accepts him as part of the Martin family. When Amanda dies, Andrew realizes that all those he cares for will also pass on. He presents ideas to Rupert to create artificial organs that not only can be used in humans to prolong their lives but also to replace Andrew's mechanical workings. Andrew gains the ability to eat, feel emotions and sensations, and even have sexual relationships, resulting in him and Portia falling in love. Andrew petitions the World Congress to recognize him as a human as to allow him to marry Portia, but the body expresses concern that an immortal human will cause jealousy from others. Many years later when Portia is nearly 75 years old, Andrew returns to Rupert for one last operation: to change the artificial fluids driving his body into a blood equivalent. Rupert cautions him that the blood will not last forever, causing his body to age and will die eventually, a fate Andrew accepts. An unknown amount of years later, a now visibly aged Andrew again approaches the World Congress, with Portia as support, to appeal their past decision, wanting to be able to die with dignity. On April 2, 2205, with Andrew's body deteriorating, he and Portia are both under life support monitored by Galatea, now with a human appearance. They hold hands and watch the World Congress as they recognize Andrew as a human being, the world's oldest at 200 years, and giving all rights confirmed by that, including validating his marriage to Portia. Andrew dies during the broadcast, which is confirmed by Galatea while Portia asserts that Andrew already knew the answer. After ordering Galatea to turn off her life support, Portia soon dies, hand-in-hand with Andrew as she whispers to him "See you soon".