Following the successful cloning of Dolly the sheep in the 1990s, artificial cloning of animals has become commonplace by 2015. Human cloning is prohibited by " Sixth Day " laws, following a botched attempt. Charter pilot Adam Gibson is hired for a snowboarding excursion by Michael Drucker, billionaire owner of cloning corporation Replacement Technologies, who requires him to undergo a seemingly routine drug test. When Adam's wife informs him that their daughter's dog has died, he reluctantly visits one of Drucker's “RePet” cloning stores, while his partner Hank poses as Adam and flies Drucker to the mountains, where they are killed by an assassin, Tripp. Buying a life-size animatronic “SimPal” doll for his daughter instead, Adam returns home to discover a clone of himself with his family. Before he can intervene, Adam is abducted by Marshall, Drucker's head of security, and his agents Talia, Vincent, and Wiley. Adam escapes, killing Talia and Wiley, and goes to the police but is believed to be an escaped mental patient. Drucker, somehow alive, assures reporters that he does not intend to have the Sixth Day laws repealed. However, he and his chief scientist, Dr. Griffin Weir, have secretly already perfected illegal human cloning and revive clones of Talia and Wiley. Adam breaks out of the police station and is forced to kill Wiley again, before finding Hank at his apartment, still alive. He brings Hank to his house and contemplates killing his clone but has second thoughts and reconsiders. Marshall and Talia arrive, forcing Adam to pose as his clone to send them away. Returning to his apartment, Hank is again killed by Tripp, who is shot by Adam. A dying Tripp reveals he is an anti-cloning extremist who assassinated Drucker, the latter being subsequently cloned along with Hank. Marshall and Talia arrive, but Adam escapes in their vehicle after shooting off Talia's fingers, taking her thumb to bypass the car's biometric lock. Adam uses the thumb to sneak into Replacement Technologies and confronts Dr. Weir, whose pursuit of cloning is driven by his wife Katherine's cystic fibrosis. She reveals to her husband that she knows she is the latest in a series of clones he has made in an attempt to cure her. Weir explains that the blood and vision tests Adam underwent scanned his DNA and memories — captured as a “syncording” — in the event he needed to be cloned. He reveals Drucker was secretly cloned after dying years earlier to maintain control of his fortune, as clones have no legal rights. Believing both Adam and Hank were killed alongside Drucker, Weir cloned them to return to their lives and cover up Drucker's murder and second cloning. Weir gives Adam the syncording proving Drucker has been cloned, warning that he may go after Adam's clone and family. Adam races to Clara's school recital, where Talia and Vincent have already abducted his wife and daughter. Coming face-to-face with his own clone, Adam reveals their situation and agrees to deliver the incriminating syncording to Drucker in exchange for his family. Weir confronts Drucker, who engineered the clones, including Katherine, with shortened lifespans as an insurance policy against betrayal. Drucker kills Weir, promising to resurrect him and Katherine as clones. Sending a decoy helicopter to be destroyed, Adam lands on Drucker's helipad and wreaks havoc until he is captured. Drucker reveals that Adam is actually the clone, proven by a marking inside his eyelid, but realizes the real Adam has also infiltrated the building. While the original Adam rescues his family, his clone fights off Drucker's agents, hanging Talia and drowning Marshall while Drucker himself kills Wiley for accidentally shooting him. The mortally wounded Drucker clones himself again, but the malfunctioning equipment creates a deformed, incomplete body. Adam and his clone escape in the helicopter with his family, destroying the facility and all its syncordings as Drucker's newest clone falls to his death. The real Adam arranges for his clone, who is discovered to not have a shortened lifespan like the other clones, to start a new life in Argentina, running a satellite office of their charter business. As a parting gift, the clone gives the family Hank's RePet cat, and the real Adam gives his clone a flying send-off.

Three young astronomers are baffled once the newest team member discovers radio signals of a seemingly impossible origin on 1420.163 MHz, in the water hole. After an unexplained power surge deletes crucial recordings, the team members unite and discover that the radio signals resolve to a response to the Arecibo message, a message beamed into space via radio waves in 1974, broadcast by a spacecraft in low Earth orbit using a cloaking system that renders the craft invisible on the visual spectrum but visible in infrared. After the team race to a local radio telescope array to get a new battery when a low battery threatens to halt their investigation, it turns out that the team were the first to receive and identify the message. At the finale, SETI coordinates a global message to be beamed to the craft: "Welcome to Earth", at which point the craft decloaks.

The remake follows the plot of the original with minor changes. While the original story was set in 1980s, the remake is set in 2010s, some of the scenes were altered, and the two new protagonists are different from their 1986 counterparts. A renowned cellist Vladimir Chizhov (Uncle Vova) and his teenage nephew Tolik meet an alien with a teleportation device. Tolik carelessly pushes a button on the device, and he and Uncle Vova are beamed to the planet Plyuk in Kin-dza-dza galaxy. The planet is a post-apocalyptic desert without resources, ruled by a brutal racist regime. The two travellers meet three locals, Bi, Wef and their robot Abradox, who travel on a pepelats and constantly try to cheat and betray the naive newcomers. Tolik and Uncle Vova have to go a long distance through the rusting world of Kin-dza-dza to find their way home.

A brilliant and driven scientist, Jake Terrell, and his wife, Maggie, along with their small team, are training dolphins to communicate with humans at their remote island research facility. They teach Alpha ("Fa"), a dolphin they have raised in captivity for four years, to speak simple English. They introduce him to a female dolphin captured from the wild, whom they name Beta ("Bea"). Fa regresses to his "native language" for a while, but soon teaches Bea to understand English, too. Terrell's research is funded by the Franklin Foundation, headed by Harold DeMilo (Fritz Weaver). An undercover government agent for hire, Curtis Mahoney (Paul Sorvino), blackmails DeMilo to allow him access to Terrell's facility under the guise of a freelance journalist writing about dolphin research. Although Terrell and his team attempt to stonewall Mahoney, he finds out the truth about Fa and Bea and threatens to publish his findings. To prevent this, Terrell agrees with DeMilo to reveal his progress to the Foundation board of directors, and travels to the mainland for a press conference. Once he and Maggie are there, the press conference is mysteriously cancelled, and Fa and Bea are stolen from the island. After the dolphins are kidnapped, Mahoney reveals that the Franklin Institute is planning to further train the dolphins to carry out a political assassination, using a magnetic limpet mine to kill the President of the United States. One of Terrell's team, David, is revealed to have been an undercover operative of the institute, and is helping them train the dolphins for the assassination attempt. Fa escapes and returns to the Terrells, and the conspirators set Bea off to place the mine on the President's yacht. Realizing what is happening, Jake tells Fa to stop Bea; Fa intercepts Bea, and redirects her to place the mine on the conspirators' boat, which is destroyed in the ensuing explosion, killing David and most of the board. Fa and Bea return to the Terrells, but as DeMilo approaches the island in a seaplane, Jake instructs Fa and Bea to escape and live free in the ocean. Fa is reluctant to go, having formed a bond with Jake and Maggie, but Jake gruffly orders him to leave; eventually, both dolphins escape, leaving Jake and Maggie awaiting DeMilo and reflecting on what happened.

In the future, United Kingdom is on the brink of war with China over the Taiwan issue. The British military needs soldiers with fluency in Chinese who are also ruthless killers. At an underground military base, scientists employed by Britain's Ministry of Defence produce a cybernetic implant that allows brain-damaged soldiers to regain lost functions. Their AI researcher Vincent McCarthy sets up a cognitive test for soldier Paul Dawson, a recipient of the cybernetic implant to rehabilitate his left hemispherectomy. Upset with Dawson's inability to remember anything about his past and his apparent lack of empathy, McCarthy ignores Dawson's repeated requests to see his mother. Dawson turns violent, kills McCarthy's assistant and wounds McCarthy, telling him that he's sorry just before being shot dead. Afterwards, Dawson's mother regularly stays on the road to the entrance of the base and tries to solicit information about her son's whereabouts, though McCarthy professes no knowledge of the incident. McCarthy's research leads to a series of more stable cyborgs. Although they lose the capability for human speech, the cyborgs develop a highly efficient method of communication that they keep secret. When researcher Ava demonstrates her latest work in artificial intelligence, McCarthy recruits her by promising her unlimited funds for her research. Thomson, the director, is suspicious of Ava's countercultural politics and sympathy for Dawson's mother but he relents when McCarthy insists that she is the only one who can provide the necessary programming for their latest project: a self-aware and conscious android. McCarthy plans to use this technology to help his daughter, Mary, who suffers from Rett syndrome, a neurological disorder. When she finds out, Ava volunteers to help and McCarthy maps her brain. During a demonstration of cybernetic arms that provide superhuman strength, amputee soldier James whispers a cry for help to Ava, who becomes suspicious of the treatment of the wounded soldiers. After she goes exploring in the base, McCarthy sternly warns her to avoid causing trouble. The warning comes too late and Thomson arranges to have her murdered by a Chinese Ministry of State Security agent, who impersonates Dawson's mother. Grieved by the loss of Ava, McCarthy insists that they use her brain scan and likeness for the new project, whom they dub "Machine." Machine turns out to be more human than they expected or even wanted; she shows regret when she accidentally kills a human and refuses orders that violate her sense of morality. As Thomson's demands on her grow more at odds with her morality, Machine becomes increasingly distressed and asks McCarthy to protect her. As antagonism grows between Thomson and McCarthy, Thomson promises that he will relent if McCarthy can prove that Machine is sentient. After Mary dies, Thomson uses her brain scans as leverage against McCarthy, threatening to destroy the scans unless McCarthy excises Machine's consciousness. Machine, who has come to love McCarthy, offers to sacrifice herself for Mary and he removes a chip from Machine's head. Thomson reneges on his deal and orders Machine to kill McCarthy. Although Machine seems at first to obey, a scientist alerts Thomson that the operation was a sham and it only disabled fail-safe routines designed to destroy Machine. Machine and the cyborgs rebel against the humans and free McCarthy. From his computer console, Thomson disables half the cyborgs but Suri, his cyborg aide, overrides his access before he can kill the rest. Thomson shoots and wounds Suri but Machine corners him in his office. Now wounded, he first orders her to obey, then begs for his life. Although Machine agrees not to kill him, she lobotomizes him as he'd attempted to do to her. After leaving Thomson for dead, Machine downloads Mary's brain scan. Machine, McCarthy and Suri escape the base; outside, McCarthy hands the base records to Dawson's mother and leaves to start a new life with Machine. In the final scene, McCarthy talks to a computer virtualization of his daughter and she requests to play a game with her mother. McCarthy hands the tablet to Machine, and she is then shown gazing alternately at the device and at a beautiful orange sunset over the Atlantic Ocean.

In a remote underwater facility, doctors Susan McCallister and Jim Whitlock are conducting research on mako sharks to help in the reactivation of dormant human brain cells like those found in Alzheimer's patients. After one of the sharks escapes the facility and attempts to attack a boat full of young adults, financial backers send corporate executive Russell Franklin to investigate the facility. Susan and Jim prove their research is working by testing a specific protein complex isolated from the brain tissue of their largest shark, which suddenly bites off Jim's arm upon awakening in the laboratory. Tower operator Brenda Kerns calls a helicopter that flies through heavy rain and strong winds to evacuate Jim. As Jim is being airlifted on a stretcher, the cable jams, and he is dropped into the shark pen. The largest shark grabs the stretcher, which is still attached to the cable, and uses it to pull the helicopter into the tower; the resulting explosions kill Brenda and the helicopter pilots while severely damaging the facility. Susan, Russell, shark wrangler Carter Blake, marine biologist Janice Higgins, and engineer Tom Scoggins witness the shark smash Jim's stretcher against the laboratory's main window and shatter it, drowning Jim and flooding the facility. They go to the facility's wet porch, where they plan to take a submersible to the surface. Susan confesses that she and Jim genetically engineered the sharks to increase their brain size as they were not naturally large enough to harvest sufficient amounts of the protein complex, breaking protocol and making the sharks much smarter and deadlier. In the flooded kitchen, cook Sherman "Preacher" Dudley hides in the oven from a stray shark that eats his pet parrot. The shark accidentally causes a gas leak from the oven while trying to break into it, and Preacher sneaks away and kills it by setting off an explosion with his lighter. When the group reaches the wet porch, they discover that the submersible has been damaged and is unsuitable for use. While delivering a monologue emphasizing the need for group unity, Russell is dragged into the submersible pool by the largest shark and devoured. The remaining crew opts to climb up the elevator shaft at the risk of destabilizing the pool. As they climb, explosive tremors cause the ladder to break. Janice loses her grip and falls into the water. Despite Carter's attempt to save her, a shark drags her under and devours her. The rest of the group moves on and encounters Preacher. Carter and Tom go to the flooded laboratory to activate a control panel that drains a stairway to the surface, while Susan heads to her room to collect her research materials. Carter and Tom reach the control panel, but the largest shark storms in, rips Tom apart, and damages the controls. In her room, Susan encounters another shark and electrocutes it with a power cable, accepting that she had to destroy her research in the process. Carter, Susan, and Preacher regroup and go to a decompression chamber. They swim to the surface while using oxygen tanks to bait the last shark into an attack. Upon reaching the surface, Preacher is grabbed by the shark and suffers injuries to his leg, but the shark releases him when he stabs it in the eye with his crucifix necklace. Carter realizes that the sharks have been manipulating them to methodically flood the facility so that they can ram their way through the fences at the surface and escape into the world. To keep the final shark from escaping, the three make a plan to blow it up by shooting it with a harpoon and connecting the harpoon's wire to a battery, sending a massive electric current to an explosive charge in the harpoon. Feeling guilty over causing the entire situation, Susan uses herself as bait without telling the others, cutting her hand before diving into the water. She distracts the shark with her blood, but is unable to get out of the water in time and is devoured, despite Carter's efforts to save her. Carter grabs onto the shark's dorsal fin, and Preacher shoots it with the harpoon, which accidentally pierces Carter's thigh and pins him to the shark. Carter nevertheless orders Preacher to connect the wire to the battery, and manages to free himself mere seconds before the shark rams through the fence, where it explodes as it tries to escape. Carter resurfaces and swims to shore, reuniting with Preacher. Moments later, as they sit on the edge, they see a rescue boat approaching the sinking facility. Preacher wryly advises Carter to stop dangling his legs in the water, which he immediately does.

A UFO makes an emergency landing on Earth and is taken into custody by the United States government. The occupant of the "flying saucer" turns out to be a strange cat-like alien named Zunar-J-5/9 Doric-4-7. Since the Mother Ship cannot send a rescue party before it leaves the Solar System, the cat sets about investigating how to repair the ship himself. Using a special collar that amplifies telekinetic and telepathic abilities, he follows the military to the Energy Research Laboratory (or E.R.L.), where they hope to learn how the UFO's power source works. One of the lab's scientists, Frank Wilson, attracts the cat's attention when his theory on the power source, while ridiculed by the rest of the staff, is actually on the right track. The cat follows Frank to his office, where Frank nicknames him Jake. Another scientist, Liz Bartlet, storms into his office, upset at Frank's sense of humor in light of such an important scientific discovery. Frank is able to calm her down, mostly by introducing Jake and inviting her to dinner. After Liz leaves, Jake reveals his true nature to Frank, demonstrating his abilities and offering to exchange his advanced knowledge of energy for Frank's assistance. That evening, the pair plan to break into the military base where Jake's ship is being kept, but must dodge Liz who has arrived for their date with her own cat, Lucybelle. Jake feigns being sick, allowing them to proceed to the base. At the base, Frank uses a back-up collar to fly to the top of the ship and attach a diagnostic device. Jake learns that he needs an element that he calls "Org 12". When Jake reveals the element's atomic weight, Frank realizes that "Org 12" is elemental gold. Back at Frank's apartment, Frank tells Jake that a quantity of gold costing $120,000 will repair Jake's ship. Norman Link, a colleague of Frank's, comes over to watch horse races and football games on which he has wagered money. Jake uses his powers to help Link's horse win the race, prompting Jake and Frank to convince Link to help them by parlaying all of his bets to win the money. However, Jake gets knocked out by a well-meaning vet that was brought in by Liz because she thought Jake was still sick. Frank informs Liz of the situation and the group heads to a local pool hall where Link has placed his bets. Learning the last game in the parlay was lost and desperate to raise the money needed, they agree to a game of pool with a hustler named Sarasota Slim. Frank's first attempt to use Jake's collar fails, but Jake regains consciousness in time to manipulate the final game and win the money they need to acquire the gold for Jake's ship. However, an industrial spy named Stallwood, who works for a master criminal named Olympus, has learned of their activities, as has the military. Frank and Jake manage to elude the military and the criminals, only to have Link, Liz and Lucybelle captured by Olympus and his men. They plan to ransom them back for the collar, which forces Jake to send his ship back to the awaiting Mother Ship and stay on Earth in order to help rescue his friends. Jake and Frank use a broken-down biplane to rescue Liz and Lucybelle from Olympus's helicopter, which crashes; Olympus, Stallwood and their men survive and are presumably arrested. In the final scene, Jake is allowed to stay on Earth as a representative of an off-world "friendly power", with Jake applying for and being granted United States citizenship.

About 20 years before the story takes place, solar flares irradiate the Earth, killing over 99% of the world's population. The survivors gather in a network of safe cities and build primitive humanoid robots, called Pilgrims, to help rebuild and operate in the harsh environment. These robots have two unchangeable protocols: They cannot harm any form of life and may not repair, modify, or alter themselves or other robots in any way. Initially seen as humankind's salvation, they are relegated to manual labor when they fail to stop the advance of desertification. Society has regressed due to lack of technology besides the Pilgrims, as a lack of functional aircraft or other transport prevents travel and cars are a rare commodity, and humanity is on the brink of extinction. In 2044, Jacq Vaucan—an insurance investigator for ROC, the company that manufactures Pilgrims—investigates a report from Wallace, a police officer who shot a robot he claims was modifying itself. As Jacq looks for a robot they suspect was stealing parts, it leads him outside the city. When he finds it inside a shipping container, it sets itself on fire. As he and a team open up the burned robot to see what it was hiding, they discover the robot had a rare nuclear battery that could power a robot indefinitely. They are able to power up the robot once more, but when he asks it why it set itself on fire, it burns out again. Jacq salvages the remains and speculates to Robert, his boss and brother-in-law, that there may be a "clocksmith", someone who illegally modifies robots, who is overriding the second protocol. Incredulous, Robert rejects this possibility, but offers Jacq a transfer out of the city if he can find evidence. Jacq had asked for the transfer to a city on the coast, because he feared raising his unborn child in the decaying city, even though Robert is skeptical whether the ocean still exists. Jacq's pregnant wife, Rachel, initially rejects his plans, but she eventually relents. Jacq and Wallace investigate a brothel, where they find Cleo, a modified robot that Wallace subsequently shoots in the leg. When Jacq objects, Wallace says that Cleo's owner will lead them to the clocksmith; Wallace also threatens to kill Jacq if he does not split the proceeds of the battery on the black market. Jacq follows Cleo's owner to a clocksmith named Dr. Susan Dupré, who claims not to know who altered Cleo, an action that would destroy Cleo's CPU. Jacq leaves the burned robot's CPU with her and offers to give her the battery if she can locate information on the clocksmith. When Dupré installs the modified CPU in Cleo, Cleo begins self-repairing. Dupré contacts Jacq, who alerts Robert; however, ROC intercepts Jacq's message and sends a team of assassins to Dupré's laboratory. Dupré is killed, but Jacq escapes in a car driven by Cleo. When Cleo takes them into a maze of stanchions, both cars crash; the assassins are killed, and Jacq is injured. Cleo takes Jacq with her into the desert, where they are joined by three other robots, none of whom will obey Jacq's orders. However, the first protocol forces them to prevent his death. Desperate to return to the city to be with his pregnant wife, Jacq makes contact with Robert, who sends Wallace to recover him. Wallace threatens Jacq's life and destroys two of the robots, who have objected to his actions; Jacq kills Wallace with a flare gun before he can also destroy Cleo. Wallace's partner flees after taking a battery from one of the robots. Robert's boss discloses that the predecessor to the first Pilgrim was a quantum mind created with no security protocols and no artificial restraints on its computational power. Before they deactivated it, its makers tasked it with designing the security protocols that govern Pilgrims. Robert's boss informs Robert that no one has been able to break Pilgrim security protocols, because they were created by the unrestricted quantum mind and ROC purposefully limited the computational power of all subsequent AI. ROC forces Robert to accompany a team sent to kill Jacq and the unknown clocksmith before the robots can evolve further beyond human understanding. When Robert objects to their kidnapping Jacq's wife and baby daughter, Conway, the leader, shoots him and leaves him for dead. Meanwhile, Jacq meets the robot responsible for modifying the others. The robot says that he and the other robots plan to go to the radioactive area where humans cannot go. Initially skeptical, Jacq eventually accepts that the robot naturally evolved, like humanity. The robot cannot understand why Jacq is afraid of dying, as death is a normal part of human living, just as the impending extinction of humanity is normal. "No lifeform can inhabit the planet eternally." It points out that the androids were conceived of and built by humans, so humanity will continue to exist through the robots that they created. Accepting this, Jacq gives them his battery, which they use to complete a new design, a sort of dog/insect robot. The robots repair a vehicle for Jacq, and he leaves for the city. When Conway reaches the robot outpost, he destroys two of the four robots. Jacq finds the dying Robert and returns to the outpost as Conway wounds Cleo and kills the evolved robot. Jacq kills all ROC assassins except for Conway, though he is further wounded in the battle. As Conway prepares to kill Jacq, the new robot saves his life by pushing Conway off a cliff in violation of the first protocol. Jacq fears the uninhibited robot will now attack him and prepares to shoot it, only to lower his weapon as his wife arrives with their child. He works the crane so Cleo and the new robot can cross to the other side of the canyon into the irradiated area. Jacq and his wife take a car and drive toward the city on the coast. Jacq appears to be dying of his injuries, but takes comfort in their child. As she drives Rachel suddenly breaks out into a smile and tells Jacq she can see the ocean ahead.

Sleep Dealer is set in a future, militarized world marked by closed borders, virtual labor, and a global digital network that joins minds and experiences, where three strangers risk their lives to connect with each other and break the technology barriers. Memo Cruz works at a factory, one of several sleep dealers. Workers in these factories are connected to robots across the border, so they may control them. The story is told as a flashback, as Memo remembers his home in Santa Ana Del Rio, Oaxaca. His father wants him to participate in growing crops on the meager family homestead. Memo's passion, however, is electronics and hacking. Memo and his father must trek on foot to buy water by the bag while monitored by security cameras armed with machine guns. The media on American hi-def TV shows glimpses of a technological dystopia, although in a positive light with superficial spin-doctoring. Memo is building an electronic receiver that can tap into communications as a hobby. As he continues to work on it, its range increases to faraway cities. One summer, a remote-controlled military aerial vehicle operated by the security forces of Del Rio Water catches Memo monitoring a frequency used by the drones. This act warrants a brutal attack. He disconnects in time before the drone can locate him with certainty. On another occasion, he and his brother watch a live TV broadcast about a drone action that is about to destroy a building known to be intercepting drone communication. They quickly realize that the building is their own home, where Memo has his equipment, and run to save their father, whose life is in danger. However, they are too late, and the vehicle launches a rocket at the father, wounding him. The drone pilot then faces their father, seeing him through the drone’s camera, before killing him. The drone pilot is a Mexican-American named Rudy Ramirez. After the tragedy Memo boards a bus to Tijuana to find work in order to help sustain his family. On that same bus Memo meets Luz Martínez. Memo notices that Luz has nodes on the wrist for interfacing with the digital network and asks her where he can get them for free. She tells him that he can find someone, known as a coyotek, to connect him by asking around in a certain alley. Luz has loans and may default. She makes a living by uploading memories to an online memory trading company, TruNode, where viewers pay for content. Luz uploads her memory of meeting Memo to TruNode expecting nothing to come out of it. Memo is robbed of his money during his first attempt to seek a coyotek. He finds an abandoned shack in which to stay at the edge of the city, where other node workers live. Luz gets a sale for her memory of Memo and a prepaid offer for her next memory of him. Luz finds him and learns he is out of money. She helps him get a node job at a bar that has the equipment. She is the coyotek, having learned from her ex-boyfriend, and she does him a favor. Luz tries to upload more experiences. TruNode makes her reveal feelings rather than just the story. The person who requested the information is revealed to be Ramirez working for Del Rio Water. Luz and Memo open up to each other and have connected sex. Upon receiving the next upload, Ramirez has his doubts confirmed that his work made him kill a good man. Memo discovers that Luz has been paid to upload her memories of him, and so he leaves her feeling betrayed. He works overtime at the sleep dealer, risking exhaustion. Luz writes to him and mails him a recording of her memories as a parting gift. In the meantime, Ramirez has crossed the fortified US-Mexican border to meet Memo. As Ramirez explains himself, Memo tries to run, perceiving danger. Ramirez catches up and explains he was under orders and offers to help. Memo rejoins Luz and recruits her help to connect Ramirez to the network. He accesses the Del Rio Water security network to control one of the company's drones. Upon discovery that Ramirez is not heeding orders, other drones pursue Ramirez. After heated aerial dogfighting, Ramirez manages to blast a hole in the dam, directly where Memo's father had once tossed a pebble in helpless frustration. Memo receives news from his home and neighboring subsistence farms, celebrations of returning ancestral waters, albeit not necessarily a permanent one. Ramirez goes farther south in Mexico as he can no longer return to his family in the US. Memo moves on with his life in Tijuana.

In New York City, cockroaches are spreading the "Strickler's disease" that is killing hundreds of the city's children. Unable to develop a cure for the disease, Dr. Peter Mann, deputy director of the CDC, recruits entomologist Dr. Susan Tyler. Dr. Tyler uses genetic engineering to create the " Judas breed", a hybrid between a mantis and a termite that releases an enzyme which accelerates the roaches' metabolism. The roaches burn calories faster than they can nourish themselves and thus starve to death; this eradicates the disease-carrying insects. Peter and Susan later marry. Three years later, a priest is chased and dragged underground by an assailant. The only witness is Chuy, a boy who refers to the attacker as "Mr. Funny Shoes" to his skeptical guardian, an immigrant subway shoe shiner named Manny. Later, two kids sell a "weird bug" from the subway to Susan, on which she performs tests, and realizes it is similar to the Judas breed. Initially, she believes that this is impossible since the specimens she released were all female and designed with a lifespan of only six months, which should have ensured that the breed would die off after a single generation. Before she can examine the insect further it is stolen by a figure who escapes out the window. After informing the police, she consults with her mentor, Dr. Gates, who autopsies a larger specimen found in the city's sewage treatment plants, and finds that its organs are fully formed, meaning the Judas breed is not only alive but has developed into a viable species, with a colony underneath the city. Looking for more specimens, the kids go down the tracks where they find an egg sac and are then killed by the same assailant. Meanwhile, Chuy enters the abandoned church of the dead priest to find "Mr. Funny Shoes" and is abducted. Peter, his assistant Josh Maslow and MTA officer Leonard Norton enter the maintenance tunnels to investigate. However, Peter and Leonard get stuck and send Josh for help. Susan encounters a shadowy creature in a trench coat on a train platform. She approaches the figure, which unfolds into an insect the size of a human being. The creature abducts Susan and carries her into the tunnels. Meanwhile, Josh almost finds a way out but is found by a Judas and killed. Manny also enters the tunnels in search of Chuy and comes across Susan, whom he rescues along with Peter and Leonard, and they barricade themselves inside a train car. Susan surmises that the Judas breed's accelerated metabolism has allowed them to reproduce at an accelerated rate, causing them to evolve over tens of thousands of generations within only three years, developing lungs, allowing increased size, and the ability to mimic their human prey. The group formulates a plan to get the car moving: using the remains of a dead bug to mask their scent as they work, Peter will switch the power on, and Manny will switch the tracks. Susan projects that the Judas will spread throughout the tunnels and overrun the city unless they manage to kill the colony's single fertile male. While trying to reach the track switches, Manny finds Chuy who has survived due to his imitating the clicking noises the bugs use for communication. However, before they can escape Manny is killed by the male Judas. Susan, realizing Manny has been gone too long, goes in search of him but finds only Chuy. Leonard's injured leg starts bleeding heavily and knowing the smell will incite the creatures and endanger the group, he creates a diversion that allows the others to get away, before being killed. Peter finds a dumbwaiter and puts Susan and Chuy in it, but stays behind to destroy the breed for good. He is chased into a room where hundreds are nesting and blows them all up by setting fire to a loose gas pipe, before diving underwater to safety. The male Judas escapes the blast and goes after Chuy but is distracted by Susan, who lures it into the path of an oncoming train, which runs over it. The two make it to the surface, with Susan assuming that Peter had died in the blast. She then sees what appears to be another Judas, only for it to be revealed to actually be Peter alive and well. The three then reunite and embrace one another.

Primary school teacher Gemma and her boyfriend Tom, a landscaper, visit a housing development called Yonder, where all the homes appear identical. They are shown house number 9 by an unusual real estate agent named Martin, who unsettlingly mimics Gemma's answer after asking if they have children. After a tour, Martin disappears without explanation. Gemma and Tom attempt to leave the development but inexplicably end up going back to house 9, after which the couple drives through the seemingly endless, identical streets until eventually running out of fuel. Gemma and Tom sleep in the house and attempt to escape on foot but repeatedly return to the same house. Outside, they find a box containing vacuum-sealed, flavorless food. Tom sets the house on fire and the couple sleeps on the pavement. By morning, however, the fire has left no damage, and a new box appears, this time containing an infant and a message instructing them to raise the child in order to be released. After 98 days, the child has grown rapidly to the size of a ten-year-old, mimicking Tom and Gemma and shrieking when hungry. When it calls Gemma "Mother", she denies the role, while Tom refers to the child as "it". The couple waits in the garden with a pickaxe to ambush whoever is delivering the food, but no one appears. Tom begins digging a hole in the garden while growing withdrawn. Meanwhile, the Boy watches abstract, fractal-like patterns on television. Tom locks the Boy in their car in hopes of luring whoever is responsible. However, Gemma takes pity and releases the Boy. Tom continues digging and begins sleeping in the hole. One day, the Boy disappears and returns with a strange book filled with symbols and drawings of humanoid figures with throat sacs. When Gemma asks him to mimic the person who gave him the book, he makes rasping sounds and inflates his own throat sacs. The Boy matures to resemble a young adult and Tom becomes ill. The Boy leaves each day and Gemma tries to follow him but always finds herself back at number 9. Tom continues to dig and finds a corpse in a vacuum bag. The Boy locks Gemma and Tom out of the house. Gemma pleads with the Boy for medicine for Tom but is denied. Tom dies and the Boy zips him into a vacuum bag and throws it into the hole. Gemma wounds the Boy with the pickaxe. The Boy hisses and crawls into a labyrinth under the sidewalk. Gemma follows and crashes through a door into multiple rooms in other houses with more Boys and several strangers, one of whom is dead. She lands back in number 9, weak and moaning. The Boy is cleaning the house. He carries her to a vacuum bag explaining that mothers die after raising their sons. She dies as he zips her in. The Boy buries her with Tom, and the grass reforms over the defect. He drives back to the real estate office, where an aged Martin lies dying. Martin gives the Boy his name tag and dies. The Boy zips Martin into a vacuum bag and puts him into a garbage chute disguised as a file drawer. When a couple walks in the door, the Boy greets them just as Martin did.

A man with a terminal illness has his body frozen in cryostasis and becomes the first man to be resuscitated from cryonics seventy years later in the year 2084.His on-and-off-again girlfriend is by his side as he commits suicide in order to be cryopreserved. Being an accomplished artist with a design firm under his wing, he cannot stand the randomness of his throat cancer and decides to "go" under his own volition and control. After his "resurrection" under project "Lazarus", by a company with its own agenda, he starts to question mortality and matters of soul, as well as life as a transition of matter and energy. After realizing that he only valued his own life under the threat of his imminent death, unable to cope with his new life, he decides to commit suicide. Alas, the film ends with the realization that is something he's not allowed to do.