In 2293, retired Starfleet officers James T. Kirk, Montgomery Scott, and Pavel Chekov attend the maiden voyage of the USS Enterprise -B. During the shakedown cruise, the starship is pressed into a rescue mission to save two El-Aurian refugee ships that a massive energy ribbon has snared. Enterprise saves some of the refugees before their ships are destroyed, but becomes trapped by the ribbon, and Kirk goes to a control room to help the ship escape. While Enterprise is freed, Kirk is presumed lost in space and dead after the trailing end of the ribbon tears open the ship's hull. In 2371, the crew of the USS Enterprise -D is in a holodeck computer simulation, celebrating the promotion of shipmate Worf to lieutenant commander. Captain Jean-Luc Picard learns his brother and nephew have been killed in a fire, and is distraught that the Picard family line will end with him. Enterprise receives a distress call from a stellar observatory, where an El-Aurian, Dr. Tolian Soran, launches a probe at the nearby star. The probe causes the star to implode, creating a shockwave that destroys its planetary system. Soran kidnaps Enterprise engineer Geordi La Forge and is transported off the station by a Klingon Bird of Prey belonging to the Duras sisters. Enterprise crewmember Guinan tells Picard that she and Soran were among the El-Aurians rescued in 2293. Soran—who lost his family when their homeworld was destroyed—is obsessed with returning to the energy ribbon to reach the "Nexus", an extra-dimensional realm of wish fulfillment outside normal space-time. Picard and Data determine that Soran, unable to safely fly a ship directly into the ribbon, is altering its path by removing the gravitational effects of nearby stars. Soran plans to destroy another star to bring the ribbon to the planet Veridian III, consequently killing millions on a nearby inhabited planet. Upon entering the Veridian system, Picard offers himself to the Duras sisters in exchange for La Forge but insists on being transported to Soran directly. La Forge is returned to Enterprise, but unwittingly exposes the ship's defense details through the transmitter installed in his VISOR device. The Duras sisters attack, and Enterprise sustains critical damage before destroying the Bird of Prey by triggering its cloaking device, and firing photon torpedoes when its shields drop. When La Forge reports that the starship is about to suffer a warp-core breach as a result of the attack, Commander William Riker evacuates everyone to the forward saucer section of the starship, which separates from the engineering section just before the breach occurs. The resulting shockwave sends the saucer-section crashing onto the surface of Veridian III. Picard fails to stop Soran from launching another probe. The Veridian star's resulting destruction alters the ribbon's course, and Picard and Soran enter the Nexus before the shockwave destroys Veridian III. Picard is surrounded by an idealized family, but realizes it is an illusion. He is met by an "echo" of Guinan left behind in the Nexus. Guinan sends him to meet James T. Kirk, who is safe in the Nexus. Though Kirk is initially entranced by the opportunity the Nexus offers to atone for past regrets, he realizes it lacks danger and excitement. Having learned that they can travel whenever and wherever desired through the Nexus, Picard convinces Kirk to return with him to Veridian III, shortly before Soran launches the probe. Working together, Kirk and Picard distract Soran long enough for Picard to lock the probe in place; it explodes on the launchpad and kills Soran. Kirk is fatally injured in the effort, and Picard buries him at the site. Three Federation starships arrive to retrieve the Enterprise survivors from Veridian III. Picard muses that, given the ship's legacy, the Enterprise -D will not be the last vessel to carry the name.

In the opening scene, a man who turns out to be a Triad elder is killed in what appears to be an accident. However, it is revealed that the man was actually murdered, with the supposed accident actually orchestrated by a group of killers led by the Brain (Louis Koo). The group specialises in killing their victims using elaborate schemes that mask the murders as if they were accidents. Uncle (Stanley Fung), one of the team members, accidentally leaves a cigarette butt at the crime scene, and it is found by the Brain. After an argument, Uncle vows to quit smoking afterwards. The team then gets a job from a son that wants to kill his own father, likely for insurance money. They plan an accident to kill their target via electrocution, but the plan requires for it be to raining at a specific time. The team tries to execute their plan many times but fail due to the rain falling later than necessary. During one run, Uncle smokes a cigarette and begins to show signs of Alzheimer's disease, forgetting that he made a vow to stop smoking. However, the rain falls on time, and the team decides to go forth with their plan. Uncle forgets to play his part in the murder, but the murder is successfully executed nonetheless. Unexpectedly, after the murder, a bus loses control and almost runs over the Brain. The Brain manages to get out of the bus's path, but the bus then runs over Fatty (Lam Suet), another member of the team, killing him on the scene. The Brain takes Fatty's belongings, with Fatty asking the Brain whether it really was an accident before he dies. The Brain then returns home to find police officers investigating his flat, which was broken into. The Brain becomes paranoid and is convinced that everything was a setup. He trails the son to an insurance company the next day. The Brain sees the son arguing with an insurance agent (Richie Jen) over what appears to be money, leading the Brain to suspect that the insurance agent was behind the bus accident. The Brain rents a flat on the floor directly below the insurance agent's flat, and begins to perform secret surveillance on the agent. One day, the Brain trails the client to find the Woman (Michelle Ye) picking up the payment for the job at a parking garage. However, only Fatty and the Brain should have known about the pick-up. The Woman explains to the Brain that Fatty had told her about the client, but the Brain, suspecting her betrayal, kills her and takes the money. After he leaves, as he is walking on the sidewalk, the client (the son) falls from the roof of the same building and is dead. The Brain develops further suspicion of the insurance agent, who he can see talking on the phone and later hear him talking about the client on the phone in his flat. In a later date, the Brain receives a call from Uncle for help. However, the Brain is too late and finds Uncle severely injured, apparently dropping two stories from a building near the crime scene in the opening scene. The Brain decides to take revenge against the insurance agent and devises a scheme to kill the agent by reflecting the sun's rays to blind a car to run over the agent in what would appear to be an accident. However, in the middle of the plan's execution, there is a solar eclipse, blocking the sunlight. At this time, the Brain receives a call from Uncle in the hospital, who tells the Brain that Fatty's death really was an accident. Uncle had accidentally dropped a bag of toy balls that night, which led to the loss of control of the bus. Realizing he has made a mistake and that the agent is innocent, the Brain runs and tries to cover the windshield from reflecting light. The agent sees and recognises the Brain as he is running, but the Brain is too late, and a blinded driver runs over the agent's wife, killing her. On a later date, as the Brain is leaving the rented flat, he is confronted and stabbed by the insurance agent in the staircase, who asks the Brain why he had to harm them. The Brain looks at the sky and thinks about his own wife before he dies.

During a July 2020 COVID-19 lockdown in London, friends Haley, Jemma, Radina, Emma, Caroline, and Teddy join the weekly Zoom call they have been using to stay in touch. Haley has arranged for them to partake in a virtual séance led by the medium Seylan, who emphasizes that they should not disrespect the spirits, though only Haley and Caroline takes it seriously. Teddy is forced to leave the call when his girlfriend Jinny disconnects him. Jemma claims to feel intense tension around her neck and begins to cry, explaining that she feels the presence of a school friend who killed himself by hanging. Seylan's internet cuts out and disconnects her from the call, prompting a laughing Jemma to admit that she made the story up because she was bored, which angers Haley. While they are arguing, Haley's chair is suddenly pulled across the room, to the shock of the group. A series of terrifying phenomena commence: the legs of a hanging corpse appear in Caroline's attic when she goes to investigate a noise; when Haley points her instant camera down the hallway to take a photo of her living room, it shows a similar figure hanging from the ceiling; and Emma's wine glass shatters untouched. As the girls panic, Haley gets back in touch with Seylan and explains the situation. Seylan explains that Jemma's prank, fabricating a deceased person, may have led a demon to take on the guise of the deceased person and the identity like a mask, allowing the demon to pass into the living's world. She instructs them to close the séance, but the demon interrupts her and she is disconnected again. The girls attempt to close the circle following her instructions. Relieved that the ordeal seems to be over, the group members begin preparing to leaving the call, when Caroline suddenly appears to be flung into the camera. Emma, forgetting to switch off a filter, turns her camera towards her living room, where the filter places a mask on the face of an invisible figure which then turns to look at her. She scatters flour on the floor, in which footprints approaching her appear, and she is attacked before escaping into her bedroom. Alan's body drops down behind Radina, prompting her to flee, but the demon kills her. Caroline's camera turns back on to show the demon smashing her head into her keyboard while she pleads for help before cutting out. Haley is pulled backward through the door of her room. Jemma, who lives around the corner from Haley, rushes over. Teddy returns to the call to see that only Emma remains. Unaware of everything that has occurred, Teddy believes Emma is playing a prank on him, but he is attacked by the demon after it takes the form of a horrifying humanoid figure. He is chased into his garden, where Jinny is lifted into the air and has her neck snapped. He runs away and hides, using a lighter to see where he is going, but the demon distracts him with an eerie music box his brother used to scare him with as a child. The demon knocks him down and he drops the lighter, causing a fire that burns him to death. Emma's bedroom door opens, and she throws a blanket which drapes itself over an invisible human shape. She opens her window to escape, and falls to her death. Jemma breaks into Haley's home, and the demon smashes a bottle against her head and starts to destroy the kitchen, but Jemma recovers and finds Haley hiding under her desk. They attempt to escape the house using the flash from Haley's camera to light the way. The demon appears in the final flash of light, and rushes at them as the Zoom call timer expires.

Billionaire New Yorker Damian Hale is diagnosed with terminal cancer. He finds a business card directing him to Professor Albright, who informs him about a medical procedure called "shedding", in which one's consciousness is transferred into a new body. Damian agrees to the procedure and follows Albright's instructions to stage his own public death. Albright then transfers him into a new, younger body, and prescribes medication to alleviate the vivid hallucinations which he claims are side effects of the procedure. Damian starts a new life in New Orleans under the incognito name of Edward Kidner and is quickly befriended by his neighbor Anton. He later forgets to take his medicine and has hallucinations of a woman and child. Damian (as Edward) questions Albright, who dismisses it, but accidentally mentions details of the hallucinations that Damian had not disclosed. Albright then arranges for Damian to take a vacation in Hawaii, but Damian, convinced the hallucinations are a real memory, identifies a landmark he saw in his vision and heads to a farmhouse outside of St. Louis. There, he finds the woman, Madeline, who reacts to him as her apparently deceased husband Mark. Damian plays along as Mark, though he is shocked to learn that Mark may have sold himself to Albright, in order to pay for their daughter Anna's life-saving treatment. Damian and Madeline are suddenly attacked by Albright's men, including Anton. Damian fatally wounds Anton and kills his accomplices, then flees with Madeline to pick up Anna from school. At a nearby motel, Damian then uses a laptop to research additional details regarding "shedding", and discovers that a man named Dr. Francis Jensen, now deceased, was the pioneer researcher in the field of transhumanism. In a video, Damian notices a tic Jensen shares with Albright, then sees Albright sitting next to Jensen, deducing that Jensen may have shed his consciousness into Albright's body. Damian then finds Jensen's wife, Phyllis, in a nursing home, but she has Alzheimer's and remembers nothing. Damian lures Jensen (Albright) to the facility, where he reveals that the pills are meant to fully eliminate the original personalities of the bodies used in the shedding procedure, telling Damian that without the pills, Damian's consciousness will die, and Mark's will re-emerge. Jensen later escapes when more killers arrive. Damian is almost overpowered, but Madeline wounds the attacker, who proves to be Anton in a new body. Anton reveals that he has shed multiple times. While Damian confiscates Anton's pills, Anton taunts Madeline to ask her "husband" why he cannot answer personal questions about their life. Madeline then confronts "Mark" over his lack of knowledge of their personal details, causing Damian to reveal the entire story. He takes her and Anna to his old friend Martin O'Neill and convinces Martin to arrange for Madeline and Anna to flee to the Caribbean. When he and Madeline discover Anna playing with Martin's previously deceased child Tony, Martin admits that he allowed Tony to also use shedding and that Jensen's men are coming. Damian then reveals shedding's secret to Martin, who reacts in shock and disgust. Damian distracts Jensen's men while Martin helps the others to flee. Damian again fatally injures Anton, but the other thugs realize that Damian is alone and turn back, recapturing Madeline and Anna. Damian then purposely stops taking his medicine to experience more of Mark's memories, which reveal that Jensen has a lab in an abandoned warehouse. Jensen captures him and starts to shed Anton into Mark's body. Damian, remembering that metal interferes with the process, hides a bullet casing in his mouth, causing the Shedding Machine to malfunction, preventing the transfer of Anton's consciousness. Masquerading as Anton, Damian then rescues the others. Although Jensen tries to claim that Damian needs him to survive, Martin was able to reverse-engineer the pills and give Damian the formula, allowing Damian to safely torch Jensen to death with a flamethrower. After killing Jensen, he has Martin complete Madeline and Anna's escape to the Caribbean. Damian later visits his estranged daughter Claire but does not reveal his presence inside Mark, simply giving her a letter that reconciles Claire with her father. Damian then travels to the Caribbean and fully stops taking his medicine. The real Mark then slowly re-emerges and finds a video message from Damian thanking him for the time that he gave to him. The story concludes with Mark finally reuniting with his family.

After catching his wife Amy having an affair with their friend Ted, mystery writer Mort Rainey retreats to his cabin in upstate New York. Six months later, Mort, depressed and suffering from writer's block, has delayed finalizing the divorce. A man named John Shooter arrives at the cabin and accuses Mort of plagiarizing his short story, "Sowing Season". Upon reading Shooter's manuscript, Mort discovers it is virtually identical to his own story, "Secret Window", except for the ending. The following day, Mort, who once plagiarized another author's story, tells Shooter that his story was published in a mystery magazine before Shooter's, invalidating his claim. Shooter demands proof and warns Mort against contacting the police. That night, Mort's dog, Chico, is found dead outside the cabin, along with a note from Shooter giving Mort three days. Mort reports the incident to Sheriff Newsome. Mort drives to his and Amy's house to retrieve a copy of the magazine, but he leaves because Ted and Amy are there. Mort hires private investigator Ken Karsch, who stakes out the cabin and speaks to Tom Greenleaf, a local resident. At the cabin, Shooter appears and demands that Mort revise the ending of his story, giving it Shooter's twist, in which the protagonist kills his wife. When a fire destroys Amy and Mort's house, and presumably the magazine, Mort tells the police that he has an enemy. Mort and Karsch agree to confront Shooter but first plan to meet up with Greenleaf at the local diner the next morning, but neither Karsch nor Greenleaf show up. On his way home, Mort encounters Ted, who demands that Mort sign the divorce papers. Believing Shooter is in Ted's employ, Mort refuses. Later, Shooter summons Mort; when he arrives, Mort finds Karsch and Greenleaf dead. Shooter tells Mort he killed the two men because they "interfered." He warns Mort that he has implicated him in their murders and implies Mort should dispose of the bodies. Mort agrees to meet Shooter at his cabin to show him the magazine containing his story, which has been sent overnight by his agent. Mort disposes of the bodies. Mort retrieves the package containing the magazine from the post office but finds that it has already been opened; the pages containing his story have been cut out. After a series of startling events, Mort realizes that Shooter is a figment of his imagination, unwittingly created to cope with his anger and carry out malevolent tasks that Mort cannot do – like killing Chico, Greenleaf, and Karsch, as well as burning down Amy's home. Amy arrives at the cabin, finding it ransacked, and she sees the word "SHOOTER" carved repeatedly on the walls and furniture. Mort appears, having been taken over by the "Shooter" persona. Amy realizes the name "Shooter" represents Mort's desire to "SHOOT HER". Mort stabs Amy in the leg. Ted arrives and is killed by Mort while Amy watches helplessly. Mort approaches her while reciting the ending of "Sowing Season". Months later, Mort has recovered from his writer's block, and his passion for life has returned. He is feared and shunned in town because of the rumors about the murders. Sheriff Newsome arrives and tells Mort that he is the prime suspect and that the bodies will eventually be found. Mort passively dismisses the threat and tells Newsome that the ending to his new story is "perfect". It is implied that Amy and Ted's bodies are buried under the corn growing in Mort's garden.

In 1974 Oregon, a young girl with a Polaroid camera follows a mysterious voice and encounters an erratic man in pale makeup. Twenty years later, FBI agent Lee Harker is assigned by her supervisor, William Carter, to a case involving a series of murder–suicides in Oregon. Each case consists of a father killing his family, then himself, leaving behind a letter with Satanic glyphs signed "Longlegs", whose handwriting belongs to none of the family members. Lee exhibits possible clairvoyance and manages to decode Longlegs' letters. Further investigation reveals that each family had a 9-year-old daughter born on the 14th day of the month. The murders all occurred within six days before or after said birthday, and their respective dates form an occult triangle symbol on a calendar, with one date missing. While at home talking on the phone to her mother, Ruth, Lee receives a coded birthday card from Longlegs, warning her that revealing its source will lead to her mother's murder. Following a clue, Lee and William discover a doll containing a high-energy metal orb inside its head. After visiting a mental hospital to question Carrie Anne Camera, the sole survivor of Longlegs' murders who was visited previously by someone using Lee's name, William suspects Lee has a connection to Longlegs. Discovering that Ruth had filed a police report of an intruder approaching Lee the day before her 9th birthday, William instructs Lee to visit her. Ruth directs Lee to her childhood belongings, where she finds a Polaroid that reveals Longlegs to be the man who visited a young Lee on her birthday in the opening sequence. Lee submits the photo, leading to Longlegs' arrest. Realizing the missing calendar date is that day, Lee fears an unknown accomplice of Longlegs will carry out the murder. In an interrogation room, Longlegs claims to serve " the man downstairs " and hints at Ruth's involvement in the murders before taking his own life by repeatedly bashing his face and forehead onto the metal table. Shortly after leaving the interrogation room, Lee is informed by William that Carrie Anne has committed suicide. Agent Browning drives Lee to Ruth's home. Browning waits in the car outside while Lee searches the house, but Ruth approaches the car and fatally shoots Browning before destroying a doll resembling a young Lee, causing Lee to lose consciousness. In a vision, Lee discovers that she had been threatened by Longlegs as a child, who only spared her after Ruth pleaded for her life. In return for sparing Lee, Longlegs demanded Ruth's servitude; Ruth agreed, allowing Longlegs to live in the Harker basement and create Satanic dolls that Ruth, posing as a nun, delivered to households, causing each family's patriarch to commit familicide. Lee's doll blocked her memories of Longlegs while influencing her with his magic. Lee awakens in the basement and answers the phone, where a demonic voice warns her about William's daughter Ruby's 9th birthday party, scheduled for that day. Lee rushes to save the Carters, whose deaths would complete Longlegs' triangle. She finds Ruth has already delivered the doll and possessed the family. After William murders his wife, Anna, Lee fatally shoots him to protect Ruby. Ruth lunges at Ruby with a dagger, forcing Lee to kill her. Lee tries to destroy the doll, but her revolver misfires. She yells for an unresponsive Ruby to leave, who continues only to stare at the doll.

The film begins with a young professional suddenly going blind in his car while at an intersection, with his field of vision turning white. A seemingly kind passerby offers to drive him home. However, he then steals the blind man's car. When the blind man's wife returns home, she takes him to an ophthalmologist who can identify nothing wrong and refers him for further evaluation. The next day, the doctor goes blind, and recognizes that the blindness must be caused by a communicable disease. Around the city, more citizens are struck blind, causing widespread panic, and the government organizes a quarantine for the blind in a derelict asylum. When a hazmat crew arrives to pick up the doctor, his wife lies that she has also gone blind in order to accompany him. In the asylum, the doctor and his wife are first to arrive and agree they will keep her sight a secret. They are joined by several others, including the driver, the thief, and other patients of the doctor. At this point, the "white sickness" has become international, with hundreds of cases reported every day. The government is resorting to increasingly ruthless measures to try to deal with the epidemic, including refusing aid to the blind. As more blinded people are crammed into what has become a concentration camp, overcrowding and lack of outside support cause hygiene and living conditions to quickly degrade. The doctor serves as the representative of his ward, and his sighted wife does what she can to assist her fellow inmates without revealing her ability. Anxiety over the availability of food undermines morale and introduces conflict between the prison's wards, as the soldiers who guard the camp become increasingly hostile. A man with a handgun appoints himself "king" of his ward, and takes control of the food deliveries, first demanding the other wards' valuables, and then for the women to have sex with their men. In an effort to obtain necessities, several women reluctantly submit to being raped. One of the women is killed by her assailant, and the doctor's wife retaliates, killing the "king" with a pair of scissors. Independently, other raped women sneak to the dead king's ward and set it on fire, which rapidly engulfs the building, with many inmates dying in the ensuing chaos. The survivors who escape the building discover that the guards have abandoned their posts, and they venture out into the city. Society has collapsed, with the city's population reduced to an aimless, zombie-like struggle to survive. The doctor's wife leads her husband and a few others from their ward in search of food and shelter. She discovers a well-stocked basement storeroom beneath a grocery store, barely escaping with aid from her husband when the throng around her smell the fresh food she is carrying. The doctor and his wife invite their new "family" to their apartment, where they establish a mutually supportive long-term home. Then, just as suddenly as his sight had been lost, the driver – the first person to lose his sight – recovers his sight, indicating that the body had fought off the disease, and that the blindness is ultimately temporary. They celebrate and their hope is restored.

To escape a stalker, Sawyer Valentini moves away from her Boston home. Still paranoid and traumatized, she talks with a counselor at Highland Creek Behavioral Center, who tricks her into signing a consent form for voluntary 24-hour admission to a locked psychiatric hospital. Sawyer calls the police, who can do nothing due to the signed form. During the night, stress causes Sawyer to lash out at a patient and a staff member. Consequently, the staff psychiatrist retains her for seven more days. Another patient, Nate Hoffman, reveals to Sawyer that Highland Creek is running a scheme to exploit health insurance claims. They trick people into voluntarily committing themselves as long as the patients' insurance companies continue to pay; when insurance claims run out, the patient is "cured" and released. One day, Sawyer sees David Strine, her stalker, working as an orderly under the pseudonym George Shaw. Borrowing Nate's secret cellphone, Sawyer calls her mother Angela. David gives Sawyer a large dose of methylphenidate, causing her to appear insane. That evening, when Angela arrives to attempt to get Sawyer out, David approaches her posing as a hotel employee, and kills her. David tortures Nate then kills him with an overdose of fentanyl. Sawyer finds Nate's phone under her pillow, with images of Nate badly beaten. She alerts the staff, who dismiss and put her in solitary confinement. David visits Sawyer and says he has a secluded mountain cabin he wants to take Sawyer to. Sawyer mocks him for his inexperience with women. David later returns and reveals he faked that Sawyer's insurance ran out, changing her status to released. In a forest, the body of the real George Shaw is found. To buy time, Sawyer feigns concern that David is a virgin, and that she does not want to be his first. She convinces David to have sex with another woman and suggests Violet, who previously threatened Sawyer with a shank, and he brings her to the solitary confinement cell. Sawyer uses Violet's shank to stab David in the neck and flees as he kills Violet. He recaptures Sawyer outside, and she wakes up in the trunk of his car next to her mother's corpse. Jumping from the moving car, Sawyer flees into the woods. David catches up and breaks her ankle with a hammer. Sawyer stabs him in the eye with Angela's cross and slashes his throat with the shank. Meanwhile, it is revealed that Nate was an undercover investigative journalist sent to investigate Highland Creek. Police execute a warrant on the center and arrest the hospital administrator. Six months later, while having lunch, Sawyer sees David sitting nearby. She approaches with a knife, but upon realizing it is not him, she drops the knife and runs away.

In March 1943, when the Second World War was at its height, cryptanalysts at Bletchley Park, Buckinghamshire, have a problem: the Nazi U-boats have changed one of their code reference books used for Enigma machine ciphers, leading to a blackout in the flow of vital naval signals intelligence. The British cryptanalysts have cracked the "Shark" cipher once before, and they need to do it again to keep track of U-boat locations. The book begins with Tom Jericho returning to Bletchley after a month of recovering from a nervous breakdown brought on by his failed love affair with a coworker named Claire Romilly. Jericho immediately seeks to see her again and finds that she mysteriously disappeared a few days earlier. He enlists the help of Claire's housemate, Hester Wallace, to follow the trail of clues and learn what has happened to Claire. Mr Jericho and Miss Wallace, as they formally address each other, work to decipher intercepts stolen by Claire and determine why she took them. Jericho is closely watched by an MI5 agent, Wigram, who plays cat and mouse with him throughout the film. Meanwhile, U-boats are closing in on a convoy of thirty-seven ships from America, giving the code-breakers less than four days to find a solution to reading the changed Shark cipher. But someone else at Bletchley has a personal interest in the stolen intercepts and may be responsible for Claire's disappearance.

Quarantined in a Tokyo mental hospital, a psychology professor named Kenji Murai is visited by a group of doctors asking him about the events that led him there. Murai proceeds to explain how, despite only two of his party being dead, he was the only one to be rescued. He then relates the story of his band of day trippers on a yacht: Murai, wealthy industrialist Masafumi Kasai (the owner of the yacht), salaryman skipper Naoyuki Sakuda, his shipmate assistant Senzō Koyama, celebrity writer Etsurō Yoshida, professional singer Mami Sekiguchi, and student Akiko Sōma. A sudden storm causes the yacht to nearly capsize. Though the boat remains upright, it sustains severe damage during the storm and drifts uncontrollably. The group arrive at a seemingly deserted island and begin to explore. They come across ponds full of fresh rainwater and a forest populated by unusually-large mushrooms. As they cross the island, they come upon a wrecked ship on the shore whose sails are rotted and its interior is covered with a mysterious mold. Murai, after reading the ship's log, warns them not to eat the mushrooms because they might be poisonous since the former crew had hallucinations after eating them. Finding that the mold is killed by cleaning products, they work to clear it from the ship. In doing so, they begin to suspect that the ship was connected to nuclear tests conducted in the vicinity of the island, with the resultant fallout forcing a bizarre mutation on various organisms native to the surrounding area, including the mushrooms. As the days pass, the group grows restless as their supply of food stores starts to run low. Kasai refuses to help find a way off the island and insists on living in the captain's quarters alone. One night, as Kasai is raiding the food stores, he is attacked by a grotesque-looking man who promptly disappears after encountering the group. A drunk Yoshida decides to try eating the mushrooms for their hallucinogenic properties. After scuffling with Koyama over Mami, Yoshida pulls a gun and declares his intent to have his way with the women after murdering the others (accepting that if the mushrooms do turn him into a monster, then there will be no consequences for his actions). Subdued by the others, Yoshida is locked in the captain's quarters, ironically ousting Kasai. Kasai tries to convince Naoyuki to abscond together with the food and repaired yacht. Naoyuki violently rebukes this notion, but an unstated amount of time later hogties Kasai and flees with all the gathered food (including Koyama's secret stash that they had been hoarding to extort money from Kasai). Faced with this dire prospect, Mami frees Yoshida and they attempt to take over the ship, shooting and killing Senzō in the process. Murai and Kasai manage to take the gun from Yoshida and force the two off the ship. Some time later, Kasai is confronted by Mami, who entices him to follow her into the forest and eat the mushrooms. Perpetual rainfall has caused wild fungal growth, and Kasai realizes that those who have been eating the mushrooms have turned into humanoid mushroom creatures themselves. The mushrooms are delicious and cannot be resisted after the first bite. Kasai eats the mushrooms, hallucinates scenes of Tokyo nightlife, and falls to his knees amongst the creatures. Murai finds the yacht adrift and swims out towards it. He finds a note left behind by Naoyuki listing the names of those on the island as dead and how, having now run out of food and energy, he has decided to jump into the sea. Murai draws a large X over the note. Others who have turned into mushroom creatures attack Akiko and Murai. They are separated and Akiko is kidnapped. As Murai tracks her down, he discovers that she has been fed mushrooms and is under their influence along with Mami, Yoshida, and Kasai. Murai attempts to rescue Akiko, but he is overwhelmed by the mushroom creatures and flees without her, making his way onto the yacht and escaping the island. Several days pass later, Murai is finally rescued. As he waits in the hospital, he begins to wonder if he should have stayed with Akiko on the island. His face is revealed to show signs of being infected with fungal growths. Murai states after that it did not matter whether he stayed or not, but he would have been happier there with Akiko. The screen fades as Murai notes that humans are not much different from the mushroom creatures.

Former student radical Moses Wine now works as a private investigator. He is contacted by Lila, an ex-girlfriend from his college days, who is working in the election campaign for Miles Hawthorne, a politician who is running to be Governor of California. Lila takes Moses to meet Hawthorne's campaign coordinator Sam Sebastian, who is concerned about a fake campaign flyer supposedly showing former Berkeley radical Howard Eppis together with Hawthorne and endorsing him. Knowing that Moses was a former contemporary of Eppis, Sam hires him to find out if Eppis is behind it. Eppis was one of a notorious group of radicals known as the California Four and has been in hiding for years. Moses sets about trying to track him down by contacting some of his old associates. He is given the name of Oscar Procari Jr, the son of a businessman and a supporter of Eppis, who proves elusive. Meanwhile, Moses and Lila visit the printing company and trace the order for the flyers to an electronics store owned by a Korean man, Harold Pak Chung, who disappears after Moses tracks him to a casino. Moses then finds Lila murdered in her apartment. Later he meets with Sam, who seems more concerned about the publicity and the effect it will have on Hawthorne's campaign. Rather than be fired, Moses quits. Moses encounters a woman named Alora and discovers she is the niece of another of the California Four, Luis Vasquez, who says that her uncle met Lila on the night she died and has now disappeared. Procari's father contacts Moses and they meet. Procari says that he hasn't seen his son in years and blames Eppis for turning his son away from him. Procari offers to pay Moses to find his son, but Moses declines. Meanwhile, Sam re-hires Moses as Eppis has contacted him threatening a series of bombings but that the police think it is a hoax. Sam gives him a typewritten note with an address, which Moses visits and discovers Eppis now living a comfortable suburban lifestyle and no longer a radical. Moses is followed to the address by two hitmen, who burst in and try to kill them, but leave when Moses triggers an alarm. The hitmen try to kill Moses again at his office, but Alora and her associates ambush them. They interrogate the hitmen and find they were hired by Pak Chung and that they killed Lila when they kidnapped Vasquez, but don't know where he is being held. Moses calls the police to warn them about the bombings. Pak Chung has rigged a van with explosives and drives it by remote control while Luis Vasquez is unconscious at the wheel. Moses finds Pak Chung near one of the target sites and kills him before he can carry out the bombing. A tape recording is found nearby supposedly by Eppis claiming responsibility for the bombing. Later Sam reveals himself as Oscar Procari and that his father was behind Pak Chung and the attempt to fix the election by implicating Hawthorne with Eppis.