Louden Swain is a wrestler at Thompson High School who has just turned 18 years old. He has decided that he needs to do something truly meaningful in his life. He embarks on a mission or, in a Native American term, a vision quest. His goal is to drop two weight classes to challenge the area's toughest opponent, Brian Shute, a menacing three-time state champion from nearby rival Hoover High School, who has never been defeated in his high school career. In his zeal to drop from 190 pounds (86 kilograms) to 168 pounds (76 kg), against the wishes of his coach and teammates, he disrupts the team around him and creates health problems of his own. Meanwhile, his father has taken on a boarder named Carla from Trenton, New Jersey, who is passing through on her way to San Francisco. Louden falls in love with her and begins to lose sight of his goals as a wrestler. Worse, his drastic weight loss culminates in an unhealthy situation, where he gets frequent nosebleeds which, Louden assumes, is due to a lack of iron in his diet (and results in him having to forfeit a match he was winning). The two finally admit their love for each other, but Carla realizes she is distracting him from his goals. Carla decides to move out and continue on to San Francisco, but not before seeing Louden's big match, in which he makes a comeback from losing and pins Shute in the final seconds with an O-Goshi (over-under hip toss). As Louden celebrates his victory, he monologues to the audience "...I guess that's why we got to love those people who deserve it like there's no tomorrow. 'Cause when you get right down to it—there isn't."

Living in her rundown van while travelling around America, homeless teenager Tallulah and her boyfriend Nico survive the streets by stealing credit cards. When Nico decides it is time to go home to his mother, Tallulah expresses her dismay and argues with Nico about how she will not change her lifestyle. Tallulah is devastated to discover the next morning that Nico has left without saying goodbye. Desperate to be with him again, Tallulah drives to New York City, where Nico's mother, Margo, lives and finds her at her apartment. After informing Tallulah that she has not seen Nico in two years, Margo tells Tallulah to leave. With nowhere else to go, Tallulah steals from guests at a nearby hotel, only for the strange natured and intoxicated mother, Carolyn, to mistake Tallulah as housekeeping staff. To Tallulah's confusion, Carolyn lets her child wander around naked and play with dangerous objects and admits that she is not invested in being a mother. Carolyn leaves her toddler, Maddison (Maddy), in Tallulah's care, while she goes on a date with a man who is not her husband. Tallulah bonds with the young Maddy, bathing her and playing games, before a devastated Carolyn arrives back at the hotel, distraught that the man did not want her. After Carolyn drunkenly passes out, Tallulah prepares to leave, but impulsively decides to take a crying Maddy back to her van to spend the night until further notice. When Tallulah returns to the hotel with Maddy, she flees upon seeing the police, summoned by a panicked Carolyn, and goes to Margo's apartment. After Tallulah claims that the child is Nico's and that she is Margo's granddaughter, "Maggie," Margo reluctantly agrees to let them stay for one night. Unknown to Tallulah, Margo is struggling with her own marital problems after her ex-husband Stephen has left her for a man, Andreas, and is pressing Margo to finalize their divorce. While Tallulah and Maddy stay with Margo, the three of them bond; Tallulah reveals her fears of forming relationships and Margo admits to having trouble letting go. However, Tallulah becomes increasingly aware that the authorities are looking for her and Maddy. Meanwhile, a distressed Carolyn is questioned by a social worker, who notes that Carolyn has only expressed concern for herself so far instead of her missing child. Frustrated with their questioning, Carolyn leaves the hotel to distract herself and discovers that her husband has cancelled all her credit cards, much to her fury. During a lunch with Stephen and Andreas, Margo defends Tallulah when Stephen begins to aggressively question Tallulah's relationships with Nico and Maddy. Margo lashes out at Stephen about their marriage and the deceit involved, pointing out that when all their friends supported Stephen, Margo had been left alone to reconcile the changes in her life and losing the family she loved. On their way back to Margo's apartment, Tallulah and Carolyn notice one another as the latter goes by in a cab. Just before Carolyn catches up to them, Tallulah narrowly escapes with Maddy and Margo via the subway. When Margo demands to know why Tallulah ran, an argument ensues and Tallulah runs off with a feverish Maddy to a pier that Nico had once told Tallulah was his favorite place. Nico arrives, having finally returned to his mother in New York City. Taking Maddy to the hospital, Nico devises a plan to allow Tallulah to escape. At Margo's apartment, Carolyn and the police arrive after a tip from Stephen and Andreas, who recognized Tallulah from a newspaper article reporting Maddy's abduction. Carolyn admits to Margo that she did not want to be a mother and feels no maternal instinct, despite loving her daughter; Margo comforts her. At a subway station, Tallulah calls Margo to apologize for involving her, and the police trace the call. Tallulah tries to get on the subway in order to flee, but instead returns to Maddy and Nico at the hospital. The police, Carolyn, and Margo arrive at the hospital, where an emotional Tallulah accuses Carolyn of not wanting Maddy. After a tearful Carolyn tells her that she does want her child, Tallulah reluctantly hands Maddy back to her and is arrested by the police. As Tallulah is taken away, Margo promises to help her however she can. When Detective Richards facetiously asks Tallulah if she has a habit of taking children into protective custody, Tallulah says nothing and smiles ruefully. Some time later, Margo wanders through Central Park before lying in the grass, recalling her conversation with Tallulah about letting go. Margo starts floating away happily, but then appears frightened and grabs a tree branch.

Mercenary Martin David is hired by military biotech company, Red Leaf, to go to Tasmania and gather samples of a supposedly extinct marsupial, the thylacine (Tasmanian tiger), with further instructions to kill all remaining tigers to ensure no competing organisation will get their DNA. Posing as a university biologist, Martin lodges in the home of the Armstrong family: Lucy and her two young children, Katie and Jamie. Lucy is perpetually benumbed from prescribed medication, taken after the disappearance of her environmentalist husband, Jarrah Armstrong. Speculation surrounds Jarrah's disappearance, particularly with regard to a longstanding conflict between the local loggers who are in desperate need of jobs, and the 'greenies', a group of environmentalists who have set up road blocks to the forest to prevent its deforestation. Martin goes into the bush for twelve days at a time, setting up various steel traps and makeshift snares, while waiting patiently to see if a tiger will surface. On each excursion, Martin leaves the family a map with his coordinates, to be used to search for him if he fails to return on schedule. During his short stays at the Armstrongs' to resupply, Martin slowly befriends the children, and discovers that Lucy's medication is delivered to her by Jack Mindy, who has been unofficially looking in on the family. Martin confiscates Lucy's medication, and bathes her while she is unconscious, after realising the detrimental effects of her dependency. During one return from the bush, Martin finds Lucy has recovered from the symptoms of her addiction. Jamie provides Martin with a clue as to the tiger's whereabouts: a drawing of the tiger near trees and small bodies of water. From the drawing, Martin is able to deduce the tiger's location on his map. On his next trip out, Martin stumbles across Jarrah's skeletal remains and discovers that he had been shot through the head. Martin gives him a proper burial, but does not reveal his findings to the Armstrong family. On his return to the Armstrong house, Lucy informs him that Red Leaf had initially contracted Jarrah to locate the tiger, a pursuit he eventually abandoned in favour of taking up an environmental cause to protect wildlife and that Red Leaf wanted Jarrah to find the tiger because they believed that it had a paralysing venom in its bite. While hiking to check his traps, Martin is ambushed by a rival Red Leaf operative sent to replace him. The man binds Martin's hands and instructs Martin to lead him to the tiger's cave, but Martin instead leads the operative past one of his steel traps. The operative steps on the trap, and its metal teeth bind his leg. The operative drops both rifles. Martin frees his hands, picks up one of the rifles, and kills the operative just as the operative frees himself from the trap and lunges for the other rifle. Searching the man's pockets, Martin finds the map he left with the Armstrong's, and realises the operative has been to their house. Martin returns to the Armstrong residence to find it burnt down. Confronting Mindy, he learns that Lucy and Katie had perished in the fire that Mindy claims broke out by accident, but Jamie survived and was taken by the authorities. Martin sets out into the bush once more to find the Tasmanian tiger and put an end to Red Leaf's pursuit. He finally finds the creature and reluctantly shoots it, then proceeds to cremate it in order to remove all traces of its existence. Martin returns to town and calls Red Leaf, informing them that what they are looking for is "gone forever". He then goes to a school where Jamie sits alone on a bench. When Jamie sees Martin, he runs excitedly toward him and the two embrace.

Sam is a girl who plans to go on a weekend-long camping trip in the Catskills with her father, Chris; his recently divorced friend, Matt; and Matt's son, Dylan. Dylan, resentful of the divorce, refuses to go. Sam seems upset by this and offers to talk to Dylan, but is rebuffed. On the way there, Matt and Chris banter back and forth, with Matt making jokes and Chris teasing him. Sam sleeps in the car on the way, occasionally waking up when Chris asks her to respond to a text on his phone. The three of them get one hotel room, with Sam sleeping on a sleeping bag on the floor while the two men take the beds. At dinner, Matt teases Sam light-heartedly about her being queer, and teases Chris about having a newborn baby at home with his second wife. On the way from the hotel to the trail, Sam drives while Chris criticizes her driving. When they arrive, Chris criticizes Matt for packing too much stuff for the trail, dumping out his pack and identifying unnecessary items. The trio hikes for a while, with Sam enjoying quiet moments in nature. As they hike, Sam repeatedly has to leave the trail to change her tampon. Some time after they begin hiking, Matt realizes he had forgotten his sleeping bag in the car, and Chris makes fun of him for doing so. When she gets cell reception, Sam texts her girlfriend back home. That night, as they are making camp, three hikers come and pitch camp directly next to them. Sam wants to ask them to move, but her father says to let it go. Sam cooks ramen for Chris and Matt, who praise her cooking. After dinner, the three hikers join them around the fire, talking about previous hikes. Envious of the places they have been, Chris half-jokingly resolves to hike through China. The next day, the three continue their hike, and enjoy many quiet moments in nature. Throughout the hike, Sam often takes on responsibilities of caring for the group, such as dismantling the tent. They arrive at a picturesque overlook and spend time admiring the beauty. Matt comments that he should go on more hikes, and Chris condescendingly agrees. That night, Sam, Chris, and Matt sit around the fire telling scary stories. Chris and Matt are drinking, and are visibly intoxicated. Matt tells the story of him and Dylan's mother cheating on one another as a "spooky story" and Sam criticizes him for not taking more responsibility for his role in his marriage ending. In doing so, she criticizes her dad for dating a woman shortly after divorcing her mother, and having a newborn baby at this stage of his life. Matt and Chris praise Sam's wisdom and knowledge, and Matt tells Chris, "you got a good one." Chris goes to bed, and Sam and Matt continue talking. Matt continues to speak self-deprecatingly, with Sam offering insights. Matt calls her wise, and praises her maturity. Sam says she is going to go to bed, and jokingly offers to keep the fire going so Matt can sleep next to it, since he had forgotten his sleeping bag. Matt responds by suggesting that Sam could join him in his tent to keep him warm. Sam sits in stunned silence before leaving. The next day, Sam and Chris go off on their own and go swimming. Sam tries to tell her father about what Matt had said, but Chris brushes her off, telling her she can't be offended by what Matt says and that he wants to just have a nice day. Sam goes off on her own and cries, feeling betrayed by her father and family friend. She collects rocks, which she puts in Chris and Matt's packs. She then hikes ahead of them, going back to the car on her own. When Chris and Matt catch up, Chris is angry with Sam for leaving without them and asks her to drive. Sam agrees to drive, but locks Chris and Matt out of the car. After a few moments, she unlocks the car. Her father climbs into the passenger seat, makes eye contact with Sam, and sets a rock on the dashboard.

Benjamin (David Kross), a German high school student, is a backpacker on his first major tour. In a nightclub in Phnom Penh, he meets a young local girl, Sreykeo (played by Apinya Sakuljaroensuk), and rapidly falls in love with her. Ben opts for this love, even though Sreykeo turns out to be HIV positive and seems to be a prostitute. It is based on the true story of Sreykeo Sorvan and Benjamin Prüfer.

Felix (Gracia) is an architect who lives in a large house. He appears to be sensitive about visitors after a recent separation from his wife Vera (López). One night, a man asks to come in and use the phone. Felix allows him to do so and leaves the room for a few minutes, but then he discovers the man is nowhere to be seen. For the next few days, Felix hears strange noises in the house, suspecting the man actually never left. Felix then calls the police who are unable to find anything. He later calls Vera and asks her to visit him, eventually resulting in them having sex. But he becomes paranoid when he thinks he hears her talking to someone in the kitchen and accidentally injures her with a knife. Felix's suspicions are heightened when his neighbour's dog enters the house and appears to hear noises from upstairs too. His neighbour, Mrs Müller, runs after the dog and appears to be thrown down the stairs, killing herself and her dog in the process. The police determine that she merely slipped accidentally. Eventually, Felix encounters someone in his house and shoots him, leaving that person locked in the attic. Felix locks down his house, throws the keys in the sewer and leaves. He naps in his car until he is awakened by two children who are looking at a picture that Felix drew of the strange man. They identify him as "Martin" and points Felix towards Martin's house. Felix sneaks into Martin's house and sees Martin's wife; Claudia (also played by López) who is paralysed from the waist down following a recent accident. Felix stays hidden in her house for the next few days and knows that Martin is an archeologist who is currently away on a business trip. He also discovers that Martin has been unkind to Claudia since her accident. Felix becomes infatuated with Claudia and manages to speak to her by hiding in plain sight at a surprise birthday party. Eventually, Felix alerts Claudia and Martin's friend Bruno to his presence by breaking a vase and finding a key to the locked door of the basement. Claudia reveals to Bruno that she actually locked Martin in the basement. Felix escapes the house through the basement (getting stabbed by Bruno in the process and possibly injuring or killing Bruno and Claudia in turn), which leads to a tunnel where he finds Martin's corpse. The tunnel leads to Felix's own basement. Felix climbs upstairs and discovers that the "man" he had shot a couple of nights ago was actually Vera who, dying on the floor, reveals she is pregnant.

In Liverpool, England in 1960, art students and friends John Lennon and Stuart Sutcliffe have an altercation with a group of men outside a club, with Stu sustaining a head injury. Stu is a painter, and has joined John's rock-and-roll group the Beatles as their bass guitarist. The Beatles, their line-up comprising John, Stu, Paul McCartney, George Harrison, and Pete Best, travel by ship to Hamburg, Germany, and are introduced to the city's red-light district, the Reeperbahn. The band plays regularly at the Kaiserkeller club, and their sleeping quarters are the storeroom of the Bambi Kino, a small cinema. They meet German artist Klaus Voormann, and begin taking the drug Preludin to stay awake and play for long hours. Klaus brings his girlfriend, German photographer Astrid Kirchherr, to see the Beatles perform, and introduces her to Stu. The Beatles and Astrid go to Bar Enfer, where a drunk John begins yelling at Stu over Astrid, before being escorted out by Paul. Later, the Beatles pose for photographs taken by Astrid. A record producer from Polydor Records comes to the Kaiserkeller to see the Beatles perform, but when he arrives, Stu is on stage singing " Love Me Tender " to Astrid, and the producer leaves, unimpressed. Paul wants Stu out of the band, but John states that if Stu leaves, he leaves as well. The producer from Polydor returns to the Kaiserkeller and gives the Beatles the opportunity to perform on a record the following day. Stu says he is ill, so the other Beatles leave without him to attend the recording session, which sees them backing up singer Tony Sheridan. Astrid and Stu take photographs and have sex, and Klaus catches Stu and Astrid in bed together. Stu comes back to the Bambi Kino to find Ringo Starr, a drummer from another band, sleeping in his bunk bed. John remarks that he thought Stu had moved in "with the SS ", and informs Stu that the Beatles are now playing at the Top Ten Club. Stu chooses instead to focus on his paintings. John visits Astrid, who criticizes him for his anger and accuses him of being jealous of her relationship with Stu. The Beatles are suddenly deported when authorities discover that George is under the age of 18; Stu and Astrid bid each other goodbye. By December 1960, Stu wants to return to Hamburg, as he has not painted since he left. John thinks that Astrid was insinuating he has homosexual feelings towards Stu. By March 1961, George has turned 18, and the Beatles return to Hamburg, where Stu reunites with Astrid, who gives him a " mop top " haircut. Stu later tells John that he no longer wants to be in the band, and the two have a physical fight over Astrid. During a game of limbo at a club, Stu collapses in pain. A doctor suggests the incident is the result of a head injury. Stu proposes marriage to Astrid, and is accepted into a German art school. Stu and Astrid visit a beach with John and John's girlfriend Cynthia Powell; there, John expresses feelings for Astrid, but notes she fell in love with Stu. Stu and Astrid go to see the Beatles perform, with Paul having taken over as bassist, and the group bids the two farewell before leaving Hamburg. On 13 August 1961, Stu comes home to find Astrid and Klaus holding hands, watching the news about the Berlin Wall being erected. Enraged, Stu assaults Klaus and throws paint all over Astrid's photographs and darkroom. He later apologises to Astrid, stating that his behaviour was unlike himself. Astrid tells Stu that the Beatles will soon become famous, and that Stu will grow to resent her as a result, but Stu denies this. Stu collapses in pain and dies of a brain haemorrhage. The Beatles, with John, Paul and George now sporting mop-top hairstyles, come back to Hamburg, where Astrid informs John that Stu is dead. At the Beatles' next performance, John sings a verse from "Love Me Tender" before the group breaks into " Twist and Shout ". Astrid watches them perform before making her exit through the adoring crowd.

Kumiko is a twenty-nine year old office lady who lives in utter solitude in Tokyo. She works a dreadful, dead-end job under a boss she hates (who in turn, hates her), unable to connect to her fashionable peers, and nagged by her overbearing mother to find a man and get married. The only joys in her life come from her pet rabbit, Bunzo, and treasure hunting – which leads her to find a VHS copy of the film Fargo in a secluded cave on the shore. Convinced the film is real, Kumiko obsesses over the film, focusing on the scene in which a character played by Steve Buscemi buries a satchel of ransom money along a snowy highway, obsessively detailing and noting each aspect of the scene and the film overall. Kumiko even attempts to steal an atlas from a library, only to be caught by the security guard, who pities her and allows her to take the map of Minnesota. Under threat of being replaced, a failed reconnection with an old friend, and her mother's increasing nagging, Kumiko abandons Bunzo on a train and boards a plane to Minneapolis using her boss's company card. With a hand-stitched treasure map and a quixotic spirit, Kumiko embarks on a journey over the Pacific and through the frozen Minnesota plains to find the purported fortune. Once there, she quickly finds herself unprepared for the harsh winter, and unable to communicate due to her weak grasp of English beyond "Fargo". She is sheltered by an old lady, but sneaks off when the lady tries to convince her to stay at her home. A sheriff's deputy picks her up after passersby report her wandering through the streets, believing her to be lost. She shows him the film and he attempts to understand her, gaining her trust, but repeatedly attempts to tell her that the film is not real – later driving her to a Chinese restaurant in hopes of finding a translator, unaware that Chinese and Japanese are not mutually intelligible. While at the restaurant, Kumiko calls her mother from a payphone hoping that she would be able to wire her money only for her mother to disown her after being told she stole her boss's credit card. This leads to Kumiko breaking down in front of the officer. While buying her winter attire, Kumiko kisses the officer, but he explains that he is married and tries again to explain to her that the treasure isn't real; upset, Kumiko runs from the store and leaves in a taxi, where she plots a course to Fargo. En route, she suddenly demands the taxi to stop, then flees into the wilderness, unable to pay. She soon comes across a frozen lake where, while looking through the ice, she sees what appears to be a suitcase. Convinced that this is the treasure, she spends a long time attempting to break the ice, only to find a badly decayed oar. That night, during a snowstorm, Kumiko wanders deeper into the forest, the storm growing more and more violent until she is buried. The next morning, Kumiko emerges from the snow, and wanders through a hallucinatory landscape until she happens upon what appears to be the setting of the Fargo scene and sees the marker indicating the location of the treasure. She finds the satchel containing the money. Overjoyed with her triumph, she exclaims, "I was right after all." Bunzo appears, and, with him, she proudly walks into the distance.

Robert, a brilliant mathematician who used to work at the University of Chicago, startles his daughter Catherine while she watches TV. He gives her a bottle of champagne for her birthday, and they chat. All of this turns out to be a dream; Robert died the previous week, after a long period of crippling mental illness, and his funeral is tomorrow. Meanwhile, Hal, a former graduate student of Robert's, is reading through the latter's notebooks, which are filled with meaningless notes. Hal believes that Robert's genius may have withstood his mental illness, and clues to that genius might lie in one of his notebooks. When Hal comments on the vast amount of work Robert did, a suspicious Catherine searches Hal's backpack. A notebook eventually falls out of his coat. He explains that he wanted to give the notebook as a birthday present because it "had something written in it about her". Hal is forced to leave, giving the notebook as intended, when Catherine calls the police. The next day, Catherine's sister, New Yorker Claire, arrives in town. At the funeral, Catherine berates the many attendees for not being there for Robert during his descent into insanity. She ends by saying that she is glad her father died and leaves mid-funeral. Claire decides to sell Robert's house back to the university and wants Catherine to come with her to New York. A wake held at the house the night is attended by academic mathematicians. Hal appears and chats up Catherine. Softening up to Hal, Catherine has emotional sex with him. In flashbacks, Robert is shown invigorated, believing that he has seen the beginnings of a new mathematical proof that will prove his triumph over mental illness. In the present, Catherine gives Hal a key to Robert's desk and tells him to check the locked drawer for a notebook which contains an important proof. Excited, he shows the discovery to Catherine and Claire. He asks how long Catherine knew about this and why she did not mention it. Catherine, a promising mathematician herself, says that she wrote it and not Robert, despite evidence to the contrary. Neither Hal nor Claire believe Catherine. Hal believes that the proof's mathematics are beyond Catherine, while Claire suspects that Catherine is suffering the onset of mental illness. Hal decides to take the notebook to the math department to verify the proof's accuracy. He eventually returns as Claire and Catherine are leaving, with news that the math department believes the proof to be valid. Hal does not think that Robert wrote the proof because it employs newer mathematics and wants Catherine to explain it. Catherine remains stung by his earlier lack of trust, and the sisters leave for the airport. Hal sprints after the car and throws the book through the window and onto Catherine's lap. In another flashback, it is revealed that, while living together, Robert challenged Catherine to work on math, which she does, ultimately completing a proof, which she describes in one of the house's notebooks. Catherine goes to tell Robert about the breakthrough, but he insists that she read aloud the proof that he is working on. To Catherine's disappointment, Robert's notebook contains only ramblings. Reading his work, Catherine realizes that Robert has not overcome his mental illness. Catherine has begun to come to terms with herself, aided by Hal's confidence in her. She decides that she does not need to go with her sister to New York and leaves the airport. She returns to the University of Chicago, where she and Hal meet up and discuss the proof.