In Colorado's planned community of New Granada, Carl, Richie, and Claude hang out at "The Rec", an adult-supervised venue where teenagers can socialize. One afternoon, as The Rec closes, Carl and Richie are confronted by Police Sergeant Doberman, who suspects them of perpetrating a freeway sniping incident, but after being questioned at the station, both are released to their parents. The next day Carl befriends Cory, a new arrival who mildly rejects Carl's suggestion that they date. That evening, after learning from his father of the community's plans to nix construction of an amusement center, he walks to a local park where he meets Richie and they head to a nearby house party. But when police arrive to squelch the fun by reminding them of the newly- mposed curfew, Carl walks home alone and is assaulted by Mark, the real instigator of the freeway sniping. Meanwhile, Carl's father has been trying to interest out-of-town investors in New Grenada, but Carl thwarts his attempts by booby-trapping their car. Latcher, Carl, and Richie accompany Cory and other kids on a picnic. They take along a pistol that Cory stole during a break-in. For fun, they take turns shooting tin cans until they run out of ammo. Claude, recently arrested for possession of hash, explains that the local neighborhood pusher, a fellow student named Tip, sold it to him, but when Cory reveals Tip's recent coincidental arrest, the kids drop in and interrogate him, and he confesses that he told Doberman about giving Claude hash. Richie, Carl, and Claude dump him into a pond as Tip's mother watches in horror from a nearby tennis court. Her descriptions of Carl and the others lead to panic. Richie steals his mother's car an he and Carl flee. It all ends tragically as Doberman chases them down. Richie produces a gun and aims it at Doberman, who fires in self-defense. Richie dies. The next day, Carl sneaks home and overhears his mother on the phone discussing a community meeting at the school that night. Carl sneaks back out to notify his friends, and they decide to confront the parents there. But when police show up, locking their weapons inside their cars, the meeting turns into a nightmare. The kids chain the school's doors, light fireworks, and proceed to trash the parking lot. Then they break into patrol cars, pull out police shotguns, and blow up several vehicles, igniting fires all around. When reserve police finally arrive, the kids disperse. Doberman apprehends Carl, but Mark, the freeway sniper, shoots Doberman's car, causing it to crash and catch fire. Carl pulls himself free, leaving the unconscious Doberman inside the car to perish in the massive explosion. When next seen, Carl and others are being herded onto a school bus and driven away. From atop an overpass, Cory and Claude wave goodbye to Carl as the bus heads to a juvenile detention facility.

While driving through the Alps, thief Roger Beckerman is murdered by the local Mafia and his body disposed of in the river below. In the United Kingdom, his friend and fellow thief, Charlie Croker, is released from prison. After reuniting with his girlfriend, Lorna, to celebrate his freedom, Croker goes to meet Beckerman to discuss a heist, but is shocked to find only his widow. She insists that Croker continue with Beckerman's final masterpiece: an ambitious heist of $4 million in gold bullion, from a convoy transport in the city of Turin, Italy. Croker breaks back into prison to request financial backing from British nationalist crime lord Mr. Bridger. Initially unconvinced, Bridger soon offers support after confirming the scheme's potential. With Bridger's right-hand man, Camp Freddie, Croker recruits a crew of specialists, including Lorna, professional drivers, and lecherous computer expert Professor Simon Peach. With preparations complete, Bridger stages a funeral ceremony to meet the team in person. He discloses that the Mafia are expecting them, as they killed Beckerman over his planned heist and see the prospect of foreigners stealing Italian gold as an insult to their pride. Travelling through the Alps, Croker splits the team up to avoid raising suspicion. However, Croker's group are confronted by Mafia boss Altabani and his men, who destroy their backup escape cars and warn against continuing the plan. Croker and his men narrowly avoid being killed by threatening Bridger's reprisal against Italians living in the United Kingdom. Undeterred, the team continue to Turin. That night, the team infiltrate the Turin traffic control centre and Peach replaces a magnetic-tape data storage reel with a duplicate designed to sabotage the traffic control system. On the day of the heist, as the gold arrives at Turin airport, Croker sends Lorna to Geneva to keep her safe, promising to meet her there later. Meanwhile, Peach is arrested for molesting a woman on a tram. The convoy begins its journey through Turin, followed by Altabani. One of Croker's men sabotages the city's CCTV surveillance while the traffic control system malfunctions, disabling traffic lights and causing city-wide traffic jams that eventually force the convoy to stop outside the Museo Egizio. The crew intercept the convoy, subdue its police escort, and tow the armoured van carrying the gold into a building. While police ram the door, the crew breach the van and divide the gold between the boots of three Mini Coopers. The remaining crew escape disguised as British football fans, while Croker leads the Mini Cooper drivers out of the city, evading the police and the Mafia using an ingenious route designed by Beckerman that avoids the stalled traffic by taking them over stairs, pedestrian streets, rooftops, and through sewers. Mr. Bridger receives word of the successful heist and celebrates with his fellow inmates and prison staff, as the crew escapes Turin and conceals the Minis in the back of a modified coach. Driving through the Alps, they unload the gold and dispose of the Minis before collecting the remaining crew. During a reckless celebration, the coach driver loses control of the vehicle, resulting in the rear of the coach teetering precariously over a cliff. The crew stands at the front of the coach in an attempt to counterbalance the weight of the gold at the rear. Croker slowly crawls towards the gold which slides ever further from him. Finally, he turns to the crew and declares: "Hang on a minute lads. I've got a great idea."

In 1978, Baton Rouge pilot Barry Seal, who flies commercial jets for TWA, is recruited by CIA case officer Monty Schafer. He asks Seal, who has been smuggling Cuban cigars into the country to make a little money, to fly reconnaissance missions over Central America using an Aerostar 600, outfitted with aerial surveillance cameras. Seal accepts the job, but hides it from his wife, Lucy. In the 1980s, Schafer asks Seal to act as a courier between the CIA and General Noriega in Panama. During a mission, the Medellín Cartel picks Seal up and asks him to fly cocaine on his return flights to the US. Seal accepts and flies the cartel's cocaine to Louisiana, airdropping the drug in the countryside. The CIA turns a blind eye to the drug smuggling, but the DEA tracks Seal down. To avoid the authorities, Seal and his family relocate to Mena, Arkansas and his wife comes to accept the wealth generated by his side job. The small town becomes wealthy as the hub of US cocaine trafficking. Later, Schafer asks Seal to run guns to the Nicaraguan Contras in Honduras. Realizing the Contras are not serious about the war and just want to get rich, Seal starts trading the guns to the cartel. The CIA sets up a Contra training base in Mena and Seal flies the Contras in, but many of them escape as soon as they arrive. Seal makes so much money he buries it in suitcases in the backyard. Seal's freeloading, unemployed brother-in-law JB moves in. JB starts stealing money and is arrested with a briefcase full of cash. With JB out on bail, Seal gives him money and a plane ticket to Bora Bora for his safety. JB demands weekly cash and insults Lucy. As Seal chases after him, JB is killed by a car bomb placed by the Medellín Cartel, who had previously promised to "take care" of the JB problem. The FBI catches wind of the sudden exuberance on the streets of Mena, not helped by JB's reckless spending. Eventually, the CIA shuts down the program and abandons Seal, who is arrested by the FBI, DEA, ATF and Arkansas State Police simultaneously. Seal escapes prosecution by making a deal with the White House, which wants evidence of the Sandinistas being drug traffickers. They ask him to get photos that tie the Medellín Cartel to the Nicaraguan Sandinistas. Seal manages to get them, but the White House releases them as propaganda against the Sandinistas. Seal is prominently shown in the pictures, which leads to his indictment by the crusading state attorney general and the cartel plotting revenge. Seal is convicted but sentenced to only 1,000 hours of community service. Moving from motel to motel making video recordings detailing his experiences, Seal expects an explosion any time he starts his car. As his community service is performed at the same Salvation Army building every night, Seal cannot hide from the cartel and is shot dead by an assassin. The CIA destroys all evidence connecting them to Seal and continues smuggling, instead using Iran to get guns to the Contras, as proposed by Schafer. The film ends with Schafer getting promoted for his idea, though it is soon discovered by the public with reporters asking President Reagan and Vice President Bush about the scandal. Lucy and her kids move back to Baton Rouge, where she is seen contentedly working in fast food. One of her expensive pieces of jewelry is seen on her wrist.

In early 2009, Senator Dianne Feinstein selects Senate staffer Daniel J. Jones, who has just spent two years investigating the 2005 destruction of CIA interrogation videotapes, to lead a review of six million pages of CIA materials related to the agency's use of enhanced interrogation techniques (EITs). Jones and his team of six get to work in a sensitive compartmented information facility at a covert CIA site in Virginia. Intelligence psychologists Bruce Jessen and James Elmer Mitchell were contracted in 2002 to instruct the CIA in EITs. They started their work on Abu Zubaydah, for whom the FBI initially used the CIA rapport-building, where they started using EITs. Jones learned from an FBI agent that he gathered crucial intelligence from Zubaydah before the CIA took over the interrogations, though the agency claims that most valuable intel came from EITs. He shows evidence from the CIA's own records that prove that the agency falsely claimed that Zubaydah was a high-ranking member of Al-Qaeda to received authorization to start using EITs on him. A physician assistant with the Office of Medical Services who works at a CIA black site secretly reveals to Jones that he and other medical professionals had complained that the EITs were torture. However, they only got told to stop putting their objections in writing by the Director. Among files provided by the CIA, Jones finds the Panetta Review, a critical internal CIA review of the EIT program that was prepared in 2009 but never shared. A pundit on the news later claims that EITs had yielded good intelligence and prevented terrorist attacks. Jones stays up all night to disprove the claims, and the CIA's own records show that crucial information it is claiming to have obtained by subjecting a terrorist to torture was obtained by other means. Jones finishes the 6,200-page report, and it is approved by the Senate Intelligence Committee, chaired by Feinstein, on December 13, 2012, and sent to the CIA for final comments. Two months later, John Brennan is sworn in as the new director of the CIA. Brennan sets up meetings with CIA personnel and Jones to try to get the committee to change elements of the report. However, Jones repeatedly provides evidence to back up everything they want to change. Feinstein decides to stop this discussion with the CIA and keep the report as it is. Frustrated, Jones reveals the Panetta Review to Senator Mark Udall of the Intelligence Committee. During a Senate Intelligence Committee hearing on the nomination of the CIA general counsel, Udall asks why both the committee's reports and the Panetta Review conflict with the CIA's official position. The CIA, humiliated by Udall's revelation, conducts an illegal search and threaten to prosecute Jones for "stealing" the Panetta Review from the CIA's computers. Jones hints the search to the New York Times national security reporter, which ultimately leads Feinstein to formally accuse the CIA of unlawfully searching the Senate's computers in violation of the separation of powers. Brennan and the CIA are forced to back down, and the charges against Jones are dropped. Feinstein tells Jones that she is prepared to release a shorter summary of the report, but President Barack Obama grants the CIA broad authority to redact it first. When it becomes uncertain if the released document will have any useful information after redaction, Jones again meets with the Times reporter, but ultimately decides not to leak the report to the media. The Republican Party wins control of the Senate in the November 2014 midterm elections, meaning that the report will likely be buried forever when the new Congress is sworn in January 2015. Faced with this deadline, the Senate agrees to release the summary of the report. Feinstein gives a speech summarizing the report and its implications, and then Senator John McCain, who was tortured as a prisoner of war during the Vietnam War, gives an impassioned speech supporting the report. Jones leaves his job as a Senate staffer after the report summary released. No CIA officers are criminally charged in connection with the actions outlined in the report, with many promoted, and one later becomes the agency director.

The protagonist XXXX (otherwise unnamed) is a London cocaine distributor who abhors violence and operates with the care and professionalism of a legitimate businessman. His chief associates are his enforcer and partner Morty, and Gene, an Irish gangster who serves as his liaison to mob boss Jimmy Price. Just as XXXX is ready to retire from criminal life, he is summoned to a lunch meeting with Jimmy, who gives him two tasks. The first is to track down Charlie, the drug-addicted runaway daughter of one of Price's associates. XXXX enlists the con men Cody and Tiptoes to find her; they learn that Charlie has apparently been kidnapped, but are unable to discover who abducted her. The second task is for XXXX to oversee the purchase of one million ecstasy tablets from the "Duke", a low-level criminal who recently returned to London from Amsterdam with his girlfriend Slasher and crew of thugs led by his right-hand man Gazza. Unbeknownst to XXXX, the Duke and his crew have stolen the pills from a gang of Serbian war criminals. He meets the Duke's feckless nephew, Sidney, and finds himself attracted to his girlfriend Tammy. XXXX tries to broker the sale of the pills to Liverpool gangsters Trevor and Shanks but they refuse, informing him of their origin and that the vengeful Serbians have sent the assassin Dragan to recover the pills and kill the thieves. As the Duke had mentioned his name to the Serbians, XXXX is also a target. XXXX arranges a tryst with Tammy but is kidnapped and brought to Eddie Temple, a wealthy crime lord. Eddie explains that Charlie is his daughter, whom he has recovered; Jimmy, having recently lost a fortune due to bad investments he blames on Eddie, wanted her as a hostage until Eddie recouped his losses. Eddie gives XXXX a recording, revealing that Jimmy has been working as an informant for Scotland Yard, planning to betray XXXX to the police once the pills were sold in exchange for immunity for his own crimes and XXXX's money. Eddie demands that XXXX sell him the pills instead. XXXX assassinates Jimmy at his home, but later finds that his accountant, an associate of Jimmy's, has vanished along with XXXX's money. Confronted by Gene and Morty, he shares the evidence of Jimmy's betrayal, and the pair acknowledge him as the new acting boss. Gene shows them the corpse of the Duke, who was killed by one of his men when Slasher threatened to go to the police if Jimmy did not help them out of their situation. XXXX hires hitman Lucky, an associate of Trevor and Shanks, to ambush and kill Dragan, but Dragan kills Lucky first and makes XXXX promise to recover the pills. Sidney brings XXXX to Duke's old hideout, and, as he tries to bargain with Gazza for the pills, the police arrive. XXXX and the Duke's gang barely escape the raid, while Dragan watches from afar as the pills are confiscated. However, it turns out that XXXX arranged for the raid, with Cody and Tiptoes posing as officers to secure the pills. XXXX delivers the Duke's severed head to Dragan as a peace offering; satisfied, Dragan reports to the Serbians that the police have seized the drugs. The Serbians accept the loss, which is revealed to be a small amount in comparison to their overall manufacturing capacity. When XXXX and his crew arrive at Eddie's warehouse to sell the pills as arranged, Eddie's henchmen relieve them of the drugs at gunpoint, and Eddie welcomes him to the "layer cake" of criminal hierarchy. Having anticipated this double-cross, XXXX arranges Trevor and Shanks to gun down Eddie's men in an armed robbery, take the drugs, and sell them via Dizzy so he can settle his accounts. The gang assembles for lunch at the Stoke Park Country Club, honouring their new boss, but XXXX declines their offer of leadership and follows up on his initial plan to retire. With Tammy on his arm, he leaves the club, but is shot by a jilted yet apologetic Sidney. He collapses, bleeding out on the steps.

Michael Faraday is a history professor at George Washington University, teaching a class on American terrorism and living in Reston, Virginia, with his young son Grant. Since the death of his wife Leah, an FBI agent, Michael remains friends with her partner Whit Carver and is dating his former graduate student Brooke Wolfe. Finding a boy named Brady injured by fireworks, Michael rushes him to the hospital and meets his parents, Oliver and Cheryl Lang. They discover they are neighbours on Arlington Road and their sons become friends, joining a scouting troop together. Oliver appears to lie about an alumni letter delivered by mistake and about a blueprint Michael notices in the Langs' house. Michael becomes suspicious, intensified by Oliver's anti-government sentiments and his interest in Leah's death, but reluctantly lets Grant join Brady on a scouting trip. He presents his class with the case of Dean Scobee, who died bombing a federal building in St. Louis months earlier despite no record of terrorist activity. Bringing his students to the site of the Ruby Ridge -style standoff where Leah was killed, an emotional Michael excoriates the FBI for mistakenly identifying their target as a potential terrorist. Michael determines Oliver lied about where he attended college and was actually born William Fenimore in the same Kansas town as the deceased Oliver Lang, and 16-year-old William was arrested for trying to blow up a government office. Michael convinces the Langs' children to let him into Oliver's home office while their parents are out, and he finds the suspicious blueprint hidden behind a Gateway Arch schematic, but is nearly caught when Cheryl returns. Brooke dismisses Michael's concerns, suggesting his terrorism studies and Leah's death have made him paranoid and obsessive. Oliver confronts Michael for investigating him, explaining that the attempted bombing was a regrettable act as an angry teenager: the government cut off his family's farm from their water supply, and his father committed suicide, staged as an accident so the family could collect his life insurance payout, but they lost their land. To escape his past, William assumed the name of Oliver Lang, a childhood friend who died after college. Brooke later spots Oliver switching vehicles and follows him to a warehouse where he loads his car with mysterious cases. She leaves Michael a voicemail but is confronted by Cheryl. That night, Michael learns Brooke has been killed in an apparent car accident, and is comforted by the Langs, apologising to them for his mistrust. However, a call from Whit reveals that Michael's answering machine has been erased, and he warns Whit to investigate his suspicions about Oliver. Visiting Dean Scobee's father, who is certain his son could not have acted alone, Michael notices a photo of Dean with Grant's scout leader. He realizes Grant has been taken by Oliver, who declares that he and his sinister group killed Brooke; he murdered the real Oliver to assume his identity, and threatens Grant's life, warning Michael not to interfere with their plans. Whit finds nothing incriminating about Oliver but confirms that Michael received a call from the payphone Brooke used. Driving there, Michael spots the Langs' associates and tries to follow them but sees Grant inside their van. Michael is intercepted and beaten by Oliver, who asserts his group's mission, but Michael overpowers him and realises he intends to blow up the J. Edgar Hoover Building. Warning Whit, Michael pursues the van into the building's garage, only to discover he is chasing a decoy. He finds the bomb planted in the trunk of his car as it detonates (having unknowingly driven the bomb to its destination in his own vehicle), and Oliver watches from a distance as the blast destroys FBI headquarters. With Michael and Whit among the dead, the Langs and their conspirators successfully frame Michael as a lone wolf terrorist — just as they did with Dean Scobee — seeking revenge on the FBI for Leah's death, supported by accounts of his increasingly erratic behaviour. It is implied that the Langs and their organization had chosen Faraday long before to be their patsy because of his history, and had been planning to involve and frame him all along. The orphaned Grant moves in with relatives, unaware of his father's innocence, while Oliver and Cheryl prepare to move their family to another safe suburb for their next attack.

A man named Swaaz, short for Schwarzenegger, robs a bank and gets chased by police. He orders his child assistant, Buddy Spencer, to jump from the car with the money as he leads police elsewhere. After being chased for some time, Swaaz is eventually trapped and is killed when he accidentally shoots his car, causing it to explode. In the slums of Kampala, Uganda, a young girl runs away from home and ends up in a child trafficking ring led by a former Uganda People's Defence Force commando in the ghetto. One day, while collecting metal scraps, she is viciously assaulted by multi-millionaire Hirigi when she mistakenly takes the tire iron from his van. After enduring weeks of abuse and witnessing the death of a friend, the girl takes matters into her own hands and kills the ringleader. Ten years later, the girl has grown up to become "Bad Black", leading the same group of ghetto children to become the biggest crime syndicate in Kampala. She seduces Hirigi in a bar to exact her revenge on him. Meanwhile, Alan Ssali, an American doctor whose whole family were allegedly U.S. Army commandos, is in Kampala giving aid to the people of the slums. He encounters Bad Black, who mistakes him for a commando due to his designer dog tags. After receiving Alan's business card, Bad Black sneaks into his hotel and steals his money and passport. When the police refuse to help him, Alan receives " kung fu commando training" from his young assistant, known by his pseudonym " Wesley Snipes ", before storming through the slums to look for Bad Black. Hirigi's teenage son, Kenny, is banished by his father and goes to Black's gang in search for drugs. Hirigi tells Black about his plans to buy the ghetto and throw the gang out. Bad Black brings Hirigi to her grandmother, where it is revealed that Hirigi is her grandfather and that he has been dating a ghetto woman. Hirigi threatens Bad Black by throwing her out and runs away disgusted. One day, a drug deal between Bad Black and a rival syndicate is disrupted by police. The gangsters frantically run away only to be gunned down by Alan, who corners Bad Black and recovers his dog tags and hands her to the police. At the prison, she's intimidated by the prison gang leader Supazilla, but eventually befriends her. Bad Black then meets a fellow female inmate named Flavia who claims that her rich father banished her and that she never got to see her own child after birth before being taken to prison. Later that night, Kenny and the syndicate attempt to break Bad Black out. The following riot allows two other women to escape, but Bad Black stays with Flavia to comfort her as she is set to be released in two days; Bad Black is caught offscreen, and Kenny is subdued and captured alive. Days later, Flavia is released and is present at Bad Black's trial. Bad Black explains that her father was Swaaz and that he robbed the bank to pay for the expenses of her birth but also claims that her mother was killed during the birth. It is then revealed that Flavia is Bad Black's mother and the two hug as the court is adjourned. Three months later, Alan resumes his medical mission in Wakaliga, but with Bad Black as his nurse. Hirigi's wife suddenly appears and opens fire at the medical camp, killing Alan in the process.

In 1978, Irving Rosenfeld and Sydney Prosser work together as con artists. Sydney, posing as English aristocrat "Lady Edith Greensly", has improved the scams. Irving loves Sydney but is unwilling to leave his unstable, histrionic wife Rosalyn, fearing that he will lose contact with adopted son Danny. Rosalyn has also threatened to report Irving to the police if he leaves her. FBI agent Richie DiMaso catches Irving and Sydney in a loan scam but offers to release them if Irving can line up four additional arrests. Richie believes that Sydney is English but has proof that her aristocratic claim is fraudulent. She tells Irving that she will manipulate Richie, which distances her from Irving. Irving's friend pretends to be a wealthy Arab sheikh looking for potential investments in America. An associate of Irving's suggests that the sheikh do business with Mayor Carmine Polito of Camden, New Jersey, who is trying to revitalize gambling in Atlantic City but has struggled to find investors. Carmine seems to have a genuine desire to help the area's economy and his constituents. Richie devises a plan to make Mayor Polito the target of a sting operation despite the objections of Irving and of Richie's boss Stoddard Thorsen. Sydney helps Richie manipulate an FBI secretary to make an unauthorized wire transfer of $2 million. When Stoddard's boss Anthony Amado hears of the operation, he praises Richie's initiative, pressuring Stoddard to continue. Carmine leaves the meeting when Richie presses him to accept that cash bribe. Irving convinces him the sheikh is legitimate, expressing his dislike of Richie, and they become friends. Richie arranges for Carmine to meet the sheikh, and without consulting the others, has Mexican-American FBI agent Paco Hernandez play the sheikh, which displeases Irving. Carmine brings the sheikh to a casino party, explaining that mobsters are there and that it is a necessary part of doing business. Irving is surprised to hear that Mafia boss Victor Tellegio, right-hand man to Meyer Lansky, is present and wants to meet the sheikh. Tellegio explains that the sheikh needs to become an American citizen, and that Carmine will need to expedite the process. Tellegio also requires a $10 million wire transfer to prove the sheikh's legitimacy. Richie confesses his strong attraction to Sydney but becomes confused and aggressive when she drops her British accent and admits to being from Albuquerque, New Mexico. Rosalyn starts an affair with mobster Pete Musane, whom she met at the party. She mentions her belief that Irving is working with the IRS, causing Pete to threaten Irving, who promises to prove that the sheikh's investment is real. Irving confronts Rosalyn, who admits that she told Pete and agrees to keep quiet but wants a divorce. With Carmine's help, Richie and Irving videotape members of Congress receiving bribes. Richie assaults Stoddard in a fight over the money and soon convinces Amado that he needs the $10 million to get Tellegio, but he gets only $2 million. A meeting is arranged at the offices of Tellegio's lawyer Alfonse Simone, but Tellegio does not appear. Irving visits Carmine and admits to the scam but says that he has a plan to help him. Carmine throws Irving out, and the loss of their friendship deeply upsets Irving. The federal agents inform Irving that their $2 million is missing and that they have received an anonymous offer to return the money in exchange for Irving and Sydney's immunity and a reduced sentence for Carmine. As it turns out, Alfonse Simone, with whom Richie had arranged the wire transfer, was a con man working with Irving and Sydney. Amado accepts the deal, and Stoddard removes Richie from the case, which ends his career. The congressmen are prosecuted, and so is Carmine, who is sentenced to 18 months in prison. Irving and Sydney move in together and open a legitimate art gallery, while Rosalyn lives with Pete and shares custody of Danny with Irving.

Recent Memphis State University Law School grad Rudy Baylor has no high-paying work prospects lined up. He takes a job at a Memphis bar where he meets the bar's owner, J. Lyman "Bruiser" Stone, who is also a ruthless but successful ambulance chaser. He hires Rudy as an associate. Bruiser's associates only get paid by finding cases and working them up for trial. Rudy says he has cases, including an insurance bad faith matter he boasts could be worth several million in damages. Interested, Bruiser introduces Rudy to office paralegal Deck Shifflet, a former insurance adjuster of questionable ethics who has a law degree but has failed the bar exam six times. Bruiser employs him because he is resourceful, finds cases, is adept at gathering information, and has useful knowledge of the insurance industry. Rudy has passed the Tennessee bar exam, but is not yet properly licensed to stand as an attorney. When Bruiser fails to show up for court, Rudy attempts to argue the case, but Judge Harvey Hale scolds Rudy and tells him to first get his license. Defense attorney Leo F. Drummond offers to stand for Rudy as Rudy is sworn in before the judge. Afterwards, Rudy discovers that the FBI has raided Bruiser's office, and Bruiser has disappeared. Before fleeing, Bruiser gave Rudy and Deck $5500 each, as payment for a successful case. They pool their money to open a practice. They file suit for middle-aged couple Dot and Buddy Black, whose 22-year-old son, Donny Ray, is terminally ill with leukemia but could have been saved with a bone marrow transplant that their insurance carrier, Great Benefit, denied. Rudy, having never argued a case in court before, now faces experienced lawyers led by Drummond from the prestigious firm Tinley Britt. In chambers, Hale tells Rudy and Drummond that he is set to dismiss the case, seeing it as a "lottery" case that slows down the judicial process. However, Hale suffers a fatal heart attack before he grants the petition for dismissal. A more sympathetic Judge Tyrone Kipler, a former civil rights attorney, replaces Hale. Kipler, known by Deck as disliking Tinley Britt, immediately denies Great Benefit's petition for dismissal. He agrees to fast-track the case so Donny Ray Black's testimony can be recorded before he dies. While seeking new clients at the hospital, Rudy meets Kelly Riker, a victim of domestic violence, whose husband Cliff has beaten her numerous times causing her to require hospitalization. Rudy and Kelly become romantically involved. Rudy persuades Kelly to file for divorce. This eventually leads to a bloody confrontation with Cliff, resulting in Rudy nearly beating him to death. To keep Rudy from being implicated, Kelly orders Rudy to leave the house. She then kills Cliff herself, telling the police it was self-defense. Based on Cliff's long history of domestic abuse, the district attorney declines to prosecute Kelly. Donny Ray dies days after giving a video deposition. The case goes to trial, where Drummond gets the vital testimony of Rudy's key witness, Jackie Lemanczyk, stricken from the record as it is based on a stolen manual disallowed as evidence. Nevertheless, thanks to Rudy's determination and some clandestine reference help from now Caribbean-based fugitive Bruiser (with whom Deck is connected by intermediaries), Jackie's testimony and the Great Benefit Employee Manual are finally admitted into evidence, to Drummond's dismay. Rudy skillfully cross-examines Great Benefit's CEO, Wilfred Keeley. As part of his closing argument, he plays an emotional excerpt from Donny Ray's deposition. The jury finds for Donny Ray's family for both actual damages and enormous punitive damages that Great Benefit cannot pay. It is a great triumph for Rudy and Deck, with Keeley being arrested by the FBI and investigation proceedings into Great Benefit launched in multiple jurisdictions. The insurance company declares bankruptcy, allowing it to avoid paying punitive damages. There is no payout for the grieving parents and no fee for Rudy or Drummond. Dot expresses satisfaction at putting Great Benefit out of business, leaving the company unable to victimize other families. As this success will create unrealistic expectations for future clients, Rudy decides to abandon his new practice and become a law teacher. He and Kelly leave town together.

Former Secret Service agent Frank Horrigan learns, in a routine investigation, that a mysterious man, who calls himself " Booth ", is planning to assassinate the President of the United States (unnamed in the film). Booth soon makes a phone call to Horrigan and reveals that he knows Horrigan's history: he (Horrigan) was one of President Kennedy 's bodyguards, but failed to protect JFK on the day of his assassination. Obsessed with his failure and tormented by feelings of guilt, Horrigan has become a cynical, loveless alcoholic, but now he requests to be assigned to protect the current President. His co-worker is the playful-but-businesslike Lily Raines. Booth continues to call Horrigan from time to time, even though he knows that his calls are being traced. He calls from public telephones and allows his calls to be traced, but escapes before the Secret Service can arrest him. He needles Horrigan for his failure to protect Kennedy but also calls him a "friend". Booth escapes Horrigan and at one site, he inadvertently leaves a palm print on a passing car. The Federal Bureau of Investigation matches the print, but because the person's identity is classified, the agency chooses not to disclose it to the Secret Service. The FBI does, however, notify the Central Intelligence Agency. Horrigan learns that the assassin is in fact Mitch Leary, a skilled killer who used to work for the CIA, but suffered a mental breakdown and is now a "predator" seeking revenge on his former masters. Leary is also independently wealthy and tech-savvy. He is able to mold a zip gun out of composite material so as to evade metal detectors, and he can carry two small bullets past a metal detector concealed in a key-ring ornament. He is therefore in a position to carry a functional pistol into a fundraising event at which the President is scheduled to speak in person to the donors. D'Andrea, one of Horrigan's underlings, confides to Horrigan that he intends to retire immediately because of nightmares about a previous incident in which he was almost killed, but Horrigan persuades him to remain on the case. The two of them succeed in catching up to Leary after tracing one of his phone calls. Leary flees to the top of a building; the two bodyguards chase Leary across Washington rooftops, where Leary shoots and kills D'Andrea but saves Horrigan from falling to his death as he clings to the side of the building. As he supports Horrigan at the edge of the roof, Leary taunts Horrigan with his immediate dilemma: he (Horrigan) can save the President by shooting Leary, but then Horrigan will himself fall to his death. Horrigan is forced by circumstance to let Leary escape: choosing to "save ass", as Leary gleefully puts it, rather than save the President. Feelings of guilt over having failed to save D'Andrea on the rooftop further de-moralize Horrigan. At the fundraiser, Horrigan receives an electronic communication containing some crucial information he had requested, and realizes that Leary is there, disguised, and armed. As Leary draws his pistol and takes aim at the President, Horrigan jumps between them and saves the President's life, shouting "gun!" at the top of his voice. Leary fires his pistol, but Horrigan is wearing the regulation bullet-proof vest. While the Secret Service hustles the President to safety, Leary takes Horrigan as a hostage and pulls him into one of the hotel's external glass elevators. Horrigan is also wearing a regulation hidden microphone; he openly instructs Raines and sharpshooters to fire upon Leary. They fire but miss, shooting out the elevator's full-height windows. Horrigan takes advantage of the surprise and engages Leary in a ferocious, hand-to-hand combat in the small elevator. Leary falls through one of the ornamental windows and finds himself in the same position Horrigan was in before: hanging by his fingers from a precarious perch with only his arch-enemy to save him. Though Horrigan sincerely offers to pull him up to safety, Leary commits suicide by letting go, and falls to his death. Upon returning home to Washington, and now a widely publicized hero, Horrigan announces his retirement. Horrigan shows Raines into his apartment, where an unexpected farewell message from Leary is found on Horrigan's answering machine. They play the message, in which Leary begins to commend Horrigan on his character, but Horrigan and Raines leave the apartment before the message ends. The film ends with Horrigan and Raines enjoying a romantic interlude at the Lincoln Memorial.

Psychiatrist Margaret Ford has achieved success with her recently published book about obsessive-compulsive disorder, but feels unfulfilled. Her patient, Billy Hahn, says his life is in danger because he owes money to a criminal figure named Mike Mancuso. He threatens suicide, brandishing a gun. Margaret persuades him to surrender the weapon to her and promises to help him. That night, Margaret visits a pool hall called House of Games where she confronts Mike. He is willing to forgive Billy's debt if Margaret accompanies him to a back-room poker game and watch for the tell of George, another player: he plays with his ring when he bluffs. She agrees, and notices George playing with his ring after making a big bet. She discloses this to Mike, who calls the bet. However, George wins and demands that Mike pay the $6,000 bet, which he is unable to do. George pulls a gun, but Margaret intervenes and offers to pay the debt with a personal check. She then notices the gun is a water pistol, and realizes the entire game is a confidence trick for her money. She declines to pay, but spends the rest of the night socializing with the con men. The experience excites her and she returns the next night. She asks Mike to teach her about con games so she can write a book about it. Mike appears skeptical, but agrees. Margaret is enchanted by Mike showing her simple con tricks. Eventually, the two sneak into a hotel room and have sex. Afterward, Mike tells Margaret that con artists take a small token from every "mark" to signify their dominance. While Mike is in the bathroom, she takes a small pocket knife belonging to the room's occupant. Mike says he is late for another large-scale con that he and his associates are planning at the same hotel. Mike reluctantly allows her to tag along, posing as his wife. The con involves Mike, his partner Joey, and the "mark", a businessman, discovering a briefcase full of money and taking it to a hotel room. They discuss whether to turn it in or split it among themselves. When the "mark" withdraws to the bathroom, Margaret discovers that he is an undercover cop part of a sting operation. She warns Mike, and they attempt to escape, but the cop tries to arrest them. After a struggle, Margaret accidentally causes the cop to fatally shoot himself. She, Mike, and Joey escape to the garage, where they force Margaret to steal a car and drive past two uniformed police officers with the con men concealed in the back seat. They drive the car to a riverbank and are preparing to abandon it when they discover that the briefcase, containing $80,000 borrowed from the Mafia for the con, is gone. Margaret offers to give Mike $80,000 of her own money so he can repay the mob. Mike tells Margaret they must split up to avoid any police attention, and claims to be going into hiding. Riddled with guilt, Margaret returns to her office and refuses to see any patients. Billy arrives in high spirits, and after a brief conversation, she spots him driving away in the same red convertible that she "stole" at the hotel. She tracks him to a bar and sees Mike, all his associates, the man posing as the hotel guest, and the fake undercover policeman, discussing the night's events - a scheme to con Margaret out of $80,000. She also learns that the pocket knife she stole from the hotel room belongs to Mike, who set up the room to appear occupied. He mocks Margaret for stealing it. After overhearing Mike is going to the airport that night, she intercepts him there and says she is so worried about the police that she has withdrawn her entire life's savings. In a non-public area, she pleads with him to start a new life with her. Mike is lured by the money, then realizes he is being tricked when she inadvertently reveals she overheard the con men discussing the pocketknife. He says her money is gone, but she pulls out Billy's gun and demands that he beg for his life. Disbelieving her, Mike refuses, but Margaret shoots him in the leg. When Mike curses her, she shoots him five more times, killing him. She calmly conceals the gun and leaves. Some time later, Margaret has returned from a vacation, she has written another successful book, and is meeting her friend and colleague Dr. Littauer. They talk over lunch, and Margaret says, "When you've done something unforgivable, you must forgive yourself, and that's what I've done, and it's done". While her friend is away from the table, Margaret distracts another diner and steals a gold lighter from her purse, relishing the thrill.

In 1980, FBI agent Will Graham visits forensic psychiatrist Hannibal Lecter to discuss a case. Graham has been working with Lecter on a psychological profile of a serial killer; Graham is certain the killer is a cannibal, based on the fact that organs taken from the victims are often used in cooking. He accidentally discovers a bookmarked sweetbreads recipe in Lecter's study that includes those organs, revealing Lecter as the killer. Lecter stabs him, but Graham stabs him back with arrowheads and shoots him before falling unconscious. Lecter is tried, found not guilty by reason of insanity, and is institutionalized at the Baltimore State Hospital for the Criminally Insane. Graham, traumatized, retires to Florida with his family. Several years later, another serial killer nicknamed the "Tooth Fairy" has murdered two families in different cities – the Jacobis and the Leedses – during full moons. With another full moon approaching, special agent Jack Crawford persuades Graham to review evidence and provide leads. Graham decides to consult Lecter for further insight after telling Crawford that the Tooth Fairy has "no face" to him, and he cannot determine how he was choosing the victim families. The Tooth Fairy is Francis Dolarhyde, who kills as directed by his alternate personality, which he calls the Great Red Dragon, after the William Blake painting The Great Red Dragon and the Woman Clothed with the Sun, which is tattooed on his back. He believes that each victim brings him closer to becoming the Dragon. His psychopathology originates from childhood abuse by his grandmother. A letter from the Tooth Fairy, written on toilet paper, is discovered in Lecter's cell, expressing admiration for Lecter and suggesting that Lecter reply through the personals section of the National Tattler. Lloyd Bowman deciphers Lecter's reply, which is Will Graham's home address, sending his family into hiding. To lure out the Tooth Fairy, Graham gives an interview to Freddy Lounds, a National Tattler reporter, disparaging the killer as an impotent homosexual and that Lecter was only feigning interest in him. However, an enraged Dolarhyde kidnaps Lounds, glues him to a wheelchair, forces him to recant his allegations on tape, and sets him on fire, killing him. At his job at Chromalux, a St. Louis based home video conversion business, Dolarhyde reluctantly begins a relationship with blind co-worker Reba McClane. He struggles with genuine affection for her and his alter ego's demands that he kill her. Desperate to stop the Dragon's control over him, Dolarhyde goes to the Brooklyn Museum, tears apart the Blake painting, and eats it. Graham realizes that the Tooth Fairy knew the layout of his victims' houses from their home videos and concludes that the killer must be a Chromalux employee. He immediately goes there and is spotted by Dolarhyde. Panicked, Dolarhyde goes to Reba's house, suspecting that she may have betrayed him. He kills co-worker Ralph Mandy, takes a drugged Reba to his house, and sets it ablaze. Unable to kill her, he apparently shoots himself and Reba escapes. Graham is able to read Dolarhyde's journal and realizes he was made into a monster by systematic abuse. After an autopsy, it is revealed that Dolarhyde used Ralph's body to stage his own death. Dolarhyde infiltrates the Graham home in Florida and takes Will's son Josh hostage. To save Josh, Graham provokes Dolarhyde with his grandmother's abusive words and he attacks him. Both are wounded in a shootout, which ends when Will's wife Molly finally kills Dolarhyde. Graham, now on a sailboat with Molly and Josh, receives a letter from Lecter praising his work and bidding him well. Lecter's jailer, Dr. Frederick Chilton, tells him that he has a visitor, a young woman from the FBI.