The remake follows the plot of the original with minor changes. While the original story was set in 1980s, the remake is set in 2010s, some of the scenes were altered, and the two new protagonists are different from their 1986 counterparts. A renowned cellist Vladimir Chizhov (Uncle Vova) and his teenage nephew Tolik meet an alien with a teleportation device. Tolik carelessly pushes a button on the device, and he and Uncle Vova are beamed to the planet Plyuk in Kin-dza-dza galaxy. The planet is a post-apocalyptic desert without resources, ruled by a brutal racist regime. The two travellers meet three locals, Bi, Wef and their robot Abradox, who travel on a pepelats and constantly try to cheat and betray the naive newcomers. Tolik and Uncle Vova have to go a long distance through the rusting world of Kin-dza-dza to find their way home.

Bull is a two-year-old mutt from Chicago who frequently humps anything that piques his interest to vent his perverse instincts. He is friends with Rocco, a proud, British-accented boxer; Fetch, a wannabe-influencer dachshund; and Lucky, a dim-witted, masochistic Jack Russell, all of whom except for Bull have been neutered, which makes them a target of ridicule from the haughty, self-absorbed Borzoi show dog Sterling. Bull also harbors a crush on his neighbour, another show dog Borzoi named Honey, but is hesitant to reveal his true feelings for her. One day, Bull's owners throw him a party where they pamper him with treats and toys. But when Bull gets to the Kool-Aid-flavored toilet water, he realizes that this means he is due to be neutered the following morning, as Luther, a Great Dane, had a similar pre-neutered experience. Bull bemoans his experience, alienates his friends as they attempt to comfort him and decides to leave home in order to save himself from being sterilized. However, he soon reconsiders when he is accosted by a large clowder of alley cats, but is rescued by his friends, who came searching for him when he ran away from his home. Reconciling, Bull and his friends barely manage to escape the cats' territory. As Bull decides to return home and face his impending neutering, Rocco convinces him to have one last wild night on the town to make sure his last night of being intact will be one to remember. The foursome get into various shenanigans, such as infiltrating a dog show that Honey is competing in alongside Sterling. Bull finally musters the courage to share his attraction to her with her until she and Sterling win, causing him to sadly leave. The group soon visits "The Humphouse", a dog-friendly version of a strip club, where Lucky falls for the intersex Dobermann bouncer, Frankie. Meanwhile, Bull is seduced by Molasses, an attractive red Borzoi who reminds him of Honey. Molasses gets Bull to knot her, just as Honey, who abandoned the dog show for Bull, stumbles upon the scene and angrily confronts him. Soon, Bull, Honey and the others are captured by animal control and taken to the dog pound, where Honey is eventually released as her owners are informed whereabouts via a chipped in her fur. Realizing that Honey and Sterling will breed due to them winning the dog show, Bull and his friends escape the pound and venture to Bull's house, though Lucky deviates from the group to reunite with Frankie. Bull manages to physically intervene between Honey and Sterling as they're about to breed. However, an oblivious Sterling unknowingly sodomizes Bull, believing to be breeding with Honey. Bull confesses his feelings for her, apologizes and then leaves. Later at night, after Bull reunites with his family, Honey lures him into a backyard treehouse, where she confesses her love for him and the pair then mate. Inevitably, Bull is neutered, but not before he becomes the father of his and Honey's litter of thirteen puppies three months later. Meanwhile, Sterling discovers that he will also be neutered, much to his horror, as Luther mocks him. Later on, Honey and her own pack of friends visit The Humphouse to watch a grizzly bear twerk, to the delight of the audience and to Bull, Rocco, Fetch and Lucky's astonishment.

In prehistoric times, a meteor crashed into Earth and killed all the dinosaurs. In the present day, industrialist John Greystoke funds an expedition to Uganda to locate the meteor and harness its energy. Aided by scientist James Porter, the expedition is a failure and John decides to leave with his wife and their son John Jr. While flying over a semi-active volcano, the Greystokes' helicopter's instruments go haywire. Forced to land on the meteor, John explores a cave and discovers glowing rock formations. Using his pickaxe, John collects a sample, only to cause a chain reaction that awakens the volcano. While trying to escape, their helicopter crashes, with only John Jr. surviving. The boy is discovered by the Mountain gorilla Kala, who recently lost her child. Adopted into the troop, John chooses to be called "Tarzan," a name he made up meaning "Ape with no fur." Tarzan grows up learning the ways of the animals. After the Greystokes' disappearance, Dr. James Porter funds his expeditions by acting as a jungle guide for wealthy tourists. During a routine safari, a client wanders away from the group, attracting the attention of a cassowary. Dr. Porter's daughter Jane saves him by putting herself in danger, as she is bitten by a viper. Infatuated with the girl, Tarzan carries Jane to a shelter and cures her. The next day, she returns to her father's camp with only vague memories of the night before. Confused by exposure to humans after so long, Tarzan decides to leave his gorilla family. He wanders to the site of the helicopter crash, finds the meteor stone his father took, and builds a shelter. Years later, Tublat, the apes' abusive leader, noses around Tarzan's shelter and accidentally activates the helicopter's emergency beacon. The transmission is received by Greystoke Energies. William Clayton, the current CEO, knowing what John senior was looking for, sees a chance to make money. He promises Jane, who now works for a conservation group, to fund her organization if she accompanies him to Africa to speak with her father. In Africa, Jane is disgusted by Clayton's greed. She leaves the party, wanders into the jungle, and finds Tarzan, now a man. Astounded, he brings her to his refuge. As a mark of love, Tarzan chips off a piece of the meteor rock and gives it to her. The rest of the group tracks Jane down there, where Clayton is shocked to find the Greystoke heir alive. Seeing him as a threat to his power, Clayton starts to shoot. The couple flees and is forced to enter a valley affected by the meteor, which causes unique mutations in the local flora and fauna, turning them into monsters. Surviving many dangers, the couple reaches the meteor, where Tarzan recognizes his father's long-abandoned pickaxe. Jane realizes Tarzan's true identity as John's son. Tarzan returns to his ape tribe, where he introduces Jane to Kala and challenges Tublat for the right to lead. In the ensuing fight, Tarzan defeats Tublat and exiles him from the troop. That night, Jane and Tarzan admit to their love. Meanwhile, Clayton transforms Dr. Porter's base into an armed base filled with mercenaries. A conflict later ensues between the couple and Clayton's men. Kala runs in to protect Tarzan and Jane, getting shot in the process. Tarzan is attacked from behind and locked in a cage. Aided by his gorilla friends, he escapes, moves Kala into the jungle, and treats her wound, determined to get his revenge. Clayton moves his resources to the meteor and rigs it with explosives. Tied up there and left to die, Jane and her father are rescued by Tarzan. Dr. Porter decides to stay behind and try to stop the blasting. In the ensuing battle, Tarzan summons his animal friends with a scream, the meteor awakens the volcano and the mountain begins to give way. While Clayton and his crew fall to their demise, Jane and Tarzan escape. The couple reunites with Tarzan's family and vows to protect the forest. Meanwhile, Dr. Porter climbs up the cliff where he has gotten a piece of the meteor.

In 1998, a young LeBron James attends a youth league basketball game. His friend Malik gives him a Game Boy, which LeBron plays with until the coach demands that he concentrates on the game. LeBron misses a potential buzzer beater and is reprimanded for being unfocused. In the present day, LeBron encourages his sons, Darius and Dominic, to pursue basketball careers. While his attempts with Darius are successful, Dominic (Dom for short) aspires to become a video game developer. The Jameses are later invited to Warner Bros. Studios to discuss a film deal. LeBron rejects the idea while Dom is interested in the studio's software, particularly its AI, Al-G Rhythm. Dom and LeBron argue, with the latter revealing resentment towards his father's advice. Having become self-aware and desiring more recognition in the world, Al-G lures the duo to the server room and traps them in the studio's "Serververse". Al-G takes Dom prisoner and orders LeBron to form a basketball team to compete against his own, only earning his freedom if he wins, before sending him to Tune World. Upon his arrival, LeBron allies himself with its sole inhabitant, Bugs Bunny, who explains that Al-G persuaded the other Looney Tunes to leave their world and explore the Serververse. Using Marvin the Martian 's spaceship, the duo travel to various worlds to locate and recruit the other Looney Tunes to form the Tune Squad. Meanwhile, Al-G manipulates Dom into recreating his basketball-based video game, Dom Ball, inside the Serververse. The duo create a highly powerful team which Al-G intends to use against LeBron. In Tune World, despite Bugs's protests, LeBron insists on teaching the Tune Squad the fundamentals of basketball. They soon oppose Al-G's team, the Goon Squad, composed of avatars based on real basketball players and led by Dom. Al-G converts Tune World and the rest of the Tunes to computer animation, live streams the game and abducts real-world people, including the other Jameses, into the Serververse. Al-G threatens to delete the Looney Tunes and imprison the spectators permanently if the Goon Squad wins. The Goon Squad use their abilities to score extreme "style points", ending the first half with a 1039–37 lead. LeBron realizes his mistake and allows the Looney Tunes to use their cartoon physics during the second half. They rally and take the lead. During a time-out, LeBron apologizes to Dom for not listening to his ideas. Dom forgives LeBron and joins the Tune Squad. Al-G takes control of the game and demonstrates a new ability to undo Tune scoring, effectively thwarting any further efforts. With ten seconds left in the game and the Tune Squad down by one point, a bug in Dom Ball's code, where a character is terminated and the game crashes after a specific move is performed, is recalled. LeBron volunteers to perform the move, uncertainly declaring that it will not affect him due to originating from the real world. However, Bugs intercepts a pass and does the move himself, sacrificing his life. Bugs, Al-G and the Goon Squad are all terminated as LeBron scores the winning point with Dom's help. The Looney Tunes and their world are restored and LeBron, his family and the other real-world spectators are returned to the real world. One week later, LeBron, respecting Dom's wishes, allows him to attend the E3 Game Design Camp. He subsequently encounters Bugs, who reveals that his cartoon physics allowed him to regenerate and that his friends have also entered the real world. LeBron, having accepted the Looney Tunes as his extended family, allows them to live with him temporarily.

A rabbit named Fu has an occupation of cooking pancakes in Beijing. He is guided by kung fu master named Shifu, so he can defeat the master's enemy, Slash. Fu, surprised at finding he can channel Kung fu, confronts Slash; both defeating him and saving Penny.

Sir William "Billi" Sedgewick is a veterinarian and resides with Gordon, a goat who behaves like a dog, outside the small town of Catterness, located within the Scottish Highlands. On orders of the Scottish government, beavers have become illegal in Scotland and are to be sent to Norway. During one such removal, a lorry carrying a large group of beavers is involved in an accident, letting loose some beavers. The officers in charge of the operation, McKenzie and McTavish, manage to recapture most beavers, but one escapes. The escapee, Bessie Boo, is subsequently adopted by a family of rabbits. McKenzie, posing as a police officer, mounts an obsessive search for Bessie. Five years pass as McKenzie continues his search for Bessie. Meanwhile, Bessie and the rabbits partake in a tobogganing race. Bessie's adoptive brother, Wee Dave, and their mother fall into a river due to the former's carelessness, leading Bessie to attempt to rescue them. Billi, Gordon, and Billi's grandson, Jake, drive towards Catterness when another rabbit alerts them of the problem. Billi organises a deputation in the town square before noticing McKenzie acting strangely and questioning his identity. During the group's search, Billi finds and resuscitates Bessie's mother and soon locates Bessie and Dave approaching Baron McToff's dam. McToff, despite his protests, accepts Billi's demands to turn off the turbines. The group manages to rescue Dave, only to miss Bessie. Gordon bungee jumps down to catch Bessie but falls into the river. The group retrieves Gordon, but they are distracted by a submarine. Billi gathers a group to save Gordon with a trampoline, but Gordon gets knocked out. Victoria, a pilot duck assisting with the group's rescue, throws Billi a bottle of water, which he uses to revive Gordon. Lady Serena, Billi's daughter, hands Bessie to the submarine's pilot, but McKenzie absconds with Bessie. McKenzie then hijacks Billi's Land Rover, causing Billi to give chase in his Aston Martin and eventually on his skateboard across the Highlands. Ending up outside a military base, McKenzie tries to have Billi arrested before they are both confronted by the police. McKenzie is arrested for his crimes, while Billi promises to reunite Bessie with her family. The townspeople celebrate their victory at the Catterness Inn while Bessie gets returned to her mother. Billi and his consort, Toni Turner, leave the celebration to drive off into the moonlight.