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May
May Canady is a young woman working as a veterinary assistant. As a child, she endured bullying and ostracism due to her lazy eye; although her optometrist has fixed it via glasses and corrective lenses, May still struggles to connect with others socially in her adulthood. When May was a child, her mother made and gifted her a glass-encased doll named Suzie, giving her the advice "if you can't find a friend, make one" and instructing her to never remove Suzie from the case. As an adult, May maintains that Suzie is her only true friend.
May becomes infatuated with a local mechanic named Adam, finding his hands especially attractive. She eventually introduces herself to him, and they begin to date. May's colleague, Polly, also shows an interest in her. One day, May remarks that Polly has a beautiful neck. During their flirtation, Polly gives May a cat named Lupe.
May invites Adam to her apartment, where he shows her a short film, titled Jack and Jill, that he made while in college about two young lovers who go on a picnic and end up cannibalizing each other. May becomes aroused by the film. While passionately kissing, she bites Adam's lip, drawing blood. Disturbed, Adam abruptly leaves. Humiliated, May berates Suzie and shoves her into the cupboard.
May begins volunteering at a day care center for blind children, where she takes a liking to a sullen young girl named Petey, who makes her a clay ashtray with May's name pressed into it. Feeling abandoned by Adam, May responds to Polly's advances and they start a relationship. May overhears Adam expressing disgust with her to his friends. Devastated, she visits Polly, but finds her with another woman named Ambrosia. At home, May seeks comfort from Lupe; when Lupe ignores her, May angrily throws Petey's ashtray at her, killing the cat and shattering the ashtray. May soon develops delusions that Suzie is talking to her.
May takes Suzie to the day care center, introducing her to the children as her best friend. The children attempt to take Suzie out of her case despite May's protests, ultimately shattering the case, injuring themselves and May, and destroying the doll, much to May's distress. The following day, May meets a young punk and invites him to her house, where she notices and compliments a tattoo of Frankenstein's monster on his arm. Upon discovering Lupe's corpse in her freezer, he calls May a "freak". May breaks down and fatally stabs him in the head with scissors. After some contemplation, May determines that she needs "more parts".
On Halloween, May, dressed in a homemade costume resembling Suzie, goes to Polly's house, where she slits Polly's throat with a pair of surgical scalpels and stabs Ambrosia in the temples. She then visits Adam and his new girlfriend, Hoop, at his house, murdering both of them with the scalpels. At home, she sculpts a life-sized patchwork doll out of the punk's arms, Polly's neck, Ambrosia's legs, Adam's hands, and Hoop's ears, using Lupe's fur as the hair. Using the shards of the ashtray to form an anagram, she names the doll "Amy". Realizing that Amy lacks eyes, May gouges out her lazy eye and places it into the doll's head. Shrieking in pain and bleeding, May repeatedly begs the doll to "see" her and collapses on the bed next to it. Her creation comes to life and caresses her face affectionately with Adam's hands, at which May smiles.