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Invasion of the Body Snatchers
An amorphous parasitic alien race abandons its dying planet and travels to Earth, taking the form of small seed pods with pink flowers upon settling.
Elizabeth Driscoll, a laboratory scientist at the San Francisco Health Department, brings one of the flowers home, and shows it to her boyfriend, Geoffrey. She awakens the next morning to find him being cold and distant while putting debris of the glass that once held the flower pod into a garbage truck.
Elizabeth confides to her colleague and friend Matthew Bennell about the unsettling changes in Geoffrey, and that she fears he is an impostor. Elizabeth mentions following him and seeing him secretly meeting with people she does not know. Matthew advises Elizabeth to talk to his psychiatrist friend David Kibner, to which she reluctantly agrees.
On the way to Kibner, a hysterical man warns Elizabeth and Matthew of danger as a mob pursues him. The couple follows the mob, only to find his dead body surrounded by emotionless onlookers. At Kibner's book promotion event, Matthew finds his friend Jack Bellicec, an aspiring writer, while Elizabeth meets Kibner, who reassures a woman who claims that her husband has changed. Kibner brushes off both women's concerns, insisting the behavior is just a case of non-commitment. Elizabeth is convinced to return home to Geoffrey.
Jack returns to the mud bath spa he runs with his wife Nancy. The two find a mysterious embryonic adult-body resembling Jack, and call Matthew to investigate. At the disturbing discovery, Matthew goes to warn Elizabeth, and discovers a semi-formed duplicate of her near her bedroom. Matthew rescues Elizabeth and alerts the police and Kibner about the events, but when they arrive, Jack and Elizabeth's duplicates have disappeared.
Elizabeth suspects the flowers are involved, but is unable to examine one at the health department offices. In the meantime Matthew tries in vain to alert the authorities. After encountering several doppelgangers, Matthew, Elizabeth, Jack, and Nancy hide out in Matthew's apartment. They call Kibner, who promises to help, but in fact is another duplicate. As the group fall asleep, big flower pods emerge from the garden and start birthing their replacements. They wake up, and Matthew destroys his own replacement.
The pod people (the fully formed alien replacements) pursue Matthew's group. Jack and Nancy create a distraction, sacrificing themselves, while Matthew and Elizabeth take refuge at the health department. They take speed to remain awake. Jack and Kibner's duplicates ambush and inject them with a sedative, needing them to fall asleep to be replaced. Kibner's duplicate explains the aliens' plan to replace humanity with emotionless duplicates whose only goal is survival. Matthew kills Jack's double and locks Kibner's in a freezer, then escapes with Elizabeth.
Matthew and Elizabeth find Nancy, who tricked the pod people by hiding her emotions. The three blend in among the duplicates. Elizabeth sees a dog-human hybrid – a byproduct of a damaged pod – and screams, alerting the pod people who emit high-pitched screams. In the commotion, Matthew and Elizabeth are separated from Nancy. Boarding a truck delivering plants to Pier 70, they find pods grown and processed in a warehouse.
Noticing a nearby ship, Matthew leaves Elizabeth (whose ankle is sprained) to investigate, only to find it being loaded with pods. Matthew returns to Elizabeth, finding her asleep. She disintegrates while her duplicate emerges from the grass. Matthew flees the duplicate, breaks into the dock warehouse, and burns down the building, destroying several plants and killing many pod people. He hides underneath the pier as pursuers search for him. A flashlight shines in his direction.
Later, Matthew resumes work in the health department, acting emotionless among the duplicated employees. While outside, Nancy calls out to him. To her horror, he points at her and emits the duplicates' high-pitched scream.